
Product Introduction
| Item | Specification |
| Product Name | Thymoquinone |
| Synonyms | 2-Isopropyl-5-methyl-1,4-benzoquinone; Thymoquinon; NSC 2228 |
| CAS Number | 490-91-5 |
| Molecular Formula | C₁₀H₁₂O₂ |
| Molecular Weight | 164.20 g/mol |
| Appearance | Yellow crystalline powder or yellow oily liquid with characteristic unique herbal aromatic odor |
| Purity (HPLC) | ≥98.0% / ≥99.0% (Pharma Grade / Research Grade, customizable) |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / NMR / Mass Spectrometry / UV Identification |
| Production Method | Natural Nigella Sativa Seed Extraction + Multi-Stage Purification & Refining |
| Melting Point | 45–47°C (lit.) |
| Boiling Point | 232°C at 760 mmHg |
| Density | 1.065 g/cm³ at 25°C |
| Flash Point | 103.9°C |
| Solubility | Very slightly soluble in water, freely soluble in ethanol, DMSO, methanol and organic solvents, compatible with cosmetic oil-phase systems |
| Core Feature | Natural plant-derived quinone active compound, powerful antioxidant and anti-inflammatory bioactivity, multi-target pharmacological effects |
| Package | 1g/5g/10g aluminum foil bag, 25g/100g fluorinated bottle; custom packaging available |
| Storage | Store at -20°C sealed, dark and dry conditions; avoid high temperature, light exposure and oxidation |
| Shelf Life | 36 months under standard low-temperature sealed storage |
Product Description
Our Thymoquinone is a high-purity natural bioactive quinone compound extracted and purified from premium Nigella Sativa (black cumin) seeds. Thymoquinone (CAS 490-91-5), chemically named 2-Isopropyl-5-methyl-1,4-benzoquinone, is the primary functional active ingredient of black seed volatile oil, accounting for the core medicinal and cosmetic value of Nigella Sativa. Different from phenolic industrial monomers such as cresol series and Guaiacol which focus on industrial synthesis and flavor modulation, Thymoquinone is a high-value natural bioactive ingredient specialized in biomedical, anti-aging and health product applications, featuring unique quinone cyclic structure and multi-target biological activity. As a professional Thymoquinone supplier, we provide high-purity, low-impurity, high-activity natural Thymoquinone raw materials for global pharmaceutical research institutions, health product manufacturers and high-end cosmetic formula developers.
Thymoquinone possesses highly differentiated functional advantages compared with traditional phenolic raw materials. Its special benzoquinone molecular structure endows it with far stronger free radical scavenging capacity than ordinary plant antioxidants, delivering outstanding antioxidant, anti-inflammatory, antimicrobial and immunomodulatory effects. Modern pharmacological studies have fully verified that Thymoquinone has significant hepatoprotective, cardioprotective, anti-tumor, anti-diabetic and neuroprotective properties, supporting multi-scenario applications in biomedical research and functional product development. In cosmetic formulas, it can effectively inhibit oxidative aging, soothe inflammatory skin problems and resist bacterial proliferation, perfectly fitting the demand for clean, natural and efficient active skincare ingredients.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Thymoquinone adopts strict natural plant extraction and multi-stage low-temperature refining purification technology. We select high-quality mature Nigella Sativa seeds as raw materials, use low-temperature solvent extraction and molecular distillation processes to fully retain active molecular structure, and completely remove plant impurities, residual wax, macromolecular invalid substances and solvent residues. The whole production process avoids high-temperature damage to active ingredients, effectively solving the problems of low purity, weak activity, impure odor and easy oxidation of ordinary crude Thymoquinone extracts. The finished product features pure natural active ingredients, stable molecular activity and excellent batch consistency, fully complying with pharmaceutical research grade, health food grade and cosmetic additive safety standards.
Every batch of Thymoquinone undergoes strict multi-dimensional quality inspection, including HPLC high-precision purity analysis, NMR structural identification, mass spectrometry molecular verification and heavy metal residue detection to ensure ultra-high single-component purity and zero harmful impurity interference. The product presents uniform yellow crystal or oily state, stable chemical properties, excellent solubility in organic solvents and perfect formula compatibility. All technical indicators meet international natural active ingredient standards, supporting safe and efficient application in biomedical experiments, health product formulation and high-end cosmetic research and development.
We maintain sufficient inventory and complete qualification documents for bulk Thymoquinone supply. Whether you need high-activity standard reagents for biomedical research, core functional raw materials for anti-aging health products, or natural anti-inflammatory and antioxidant additives for cosmetic formulas, our high-purity Thymoquinone is a high-cost-performance and high-value natural active raw material choice for global buyers.
Functions & Benefits
Powerful Natural Antioxidant & Anti-Aging Effect (Core Benefit)
Thymoquinone has excellent free radical scavenging and anti-oxidation capacity, which can effectively inhibit cellular oxidative stress, reduce lipid peroxidation damage, delay skin and tissue aging. It performs better than many conventional plant antioxidants, effectively improving formula anti-aging efficacy and extending product service life.
Significant Anti-Inflammatory & Soothing Activity
As a classic natural anti-inflammatory active ingredient, Thymoquinone can inhibit the release of inflammatory factors, relieve skin redness, swelling and sensitivity problems, soothe damaged skin barriers, and provide mild and efficient anti-inflammatory repair effects for sensitive and problematic skin formulas.
Broad-Spectrum Antimicrobial & Antiseptic Performance
Thymoquinone has stable broad-spectrum inhibitory activity against common bacteria and fungi. It can assist formula antisepsis and bacteriostasis, reduce the addition of synthetic preservatives, conform to clean label trends, and improve the safety and stability of cosmetic and health product formulas.
Multi-Target Pharmacological & Organ Protective Effects
Modern studies prove that Thymoquinone has remarkable hepatoprotective, cardioprotective, neuroprotective and hypoglycemic activities. It can protect internal organs from oxidative damage, regulate immune function, and is widely used in biomedical research and functional health product development.
Anti-Tumor & Anti-Cancer Research Value
Thymoquinone has targeted inhibitory effects on a variety of tumor cell proliferation, with low toxicity and high safety. It is an important research compound for anti-tumor pharmacological experiments and new drug development, occupying an important position in biomedical frontier research.
Excellent Formula Compatibility & Stability
High-purity refined Thymoquinone has stable molecular structure, good solubility in oil-phase and organic systems, easy formula compounding, not easy to deteriorate and inactivate. It maintains long-term stable activity in skincare formulas and health product systems.
Applications
High-End Cosmetic & Skincare Formulations
Thymoquinone is widely used in anti-aging, antioxidant, soothing repair and sensitive skincare products. It effectively improves skin oxidative aging, relieves inflammatory skin problems, enhances skin barrier resistance, and creates natural and efficient clean skincare formulas.
Biomedical Research & Pharmaceutical Intermediate
Served as a standard active reagent for anti-inflammatory, anti-tumor, liver protection and immune regulation pharmacological experiments. It is an important key intermediate and research raw material for new natural drug development and biomedical mechanism research.
Functional Health Care Products Development
Applied in the formulation of antioxidant, liver-protecting, hypoglycemic and immune-regulating health products. Relying on its natural multi-biological activity, it provides safe and efficient functional raw material support for high-end health food and nutritional supplements.
Natural Antibacterial Preservative & Additive
Used as a natural antibacterial and antiseptic additive for daily chemical and functional products. It replaces part of synthetic preservatives, improves product safety, inhibits microbial growth, and stabilizes formula quality.
Laboratory Scientific Research & Custom Synthesis
Provided as high-purity standard Thymoquinone monomer for plant active ingredient research, pharmacological mechanism exploration and new formula innovation experiments, supporting customized scientific research and industrial development.
FAQ
Q1: What is Thymoquinone used for?
A: Thymoquinone is the core active ingredient of natural Nigella Sativa. It is mainly used for high-end cosmetic anti-aging & soothing formulas, biomedical anti-inflammatory and anti-tumor research, functional health product development, and natural antibacterial preservative preparation.
Q2: What is the difference between Thymoquinone and phenolic products like Cresol & Guaiacol?
A: Cresol and Guaiacol are industrial phenolic monomers focused on synthesis, resin modification and flavor tuning. Thymoquinone is a natural plant-derived quinone active ingredient, focused on biological activity, skincare efficacy and biomedical research, with completely different application positioning and product attributes.
Q3: What are the core advantages of Thymoquinone?
A: Thymoquinone features natural plant source, powerful antioxidant and anti-inflammatory activity, multi-target pharmacological effects, low toxicity and high safety. It is far more effective than ordinary plant extracts and is a high-value active ingredient for high-end cosmetics and biomedical research.
Q4: How to store Thymoquinone correctly?
A: Thymoquinone is sensitive to high temperature and light and easy to oxidize and inactivate. It must be stored in sealed, dark, low-temperature (-20°C) dry environment. Strict storage conditions ensure 36 months of valid shelf life and stable biological activity.
Q5: What is the appearance of high-purity Thymoquinone?
A: High-purity Thymoquinone appears as yellow crystalline powder or yellow oily liquid at room temperature, with unique natural herbal aroma, pure color and no impurity precipitation, ensuring high formula applicability.
Q6: Can I get free Thymoquinone samples?
A: Yes, we provide free Thymoquinone samples for cosmetic formula debugging, biomedical experimental research and health product development. Bulk orders support customized purity and packaging to meet high-end research and industrial production needs.





