Product Introduction
| Item | Specification |
| Product Name | Caffeic Acid |
| Synonyms | 3,4-Dihydroxycinnamic acid; 咖啡酸; 3,4-二羟基肉桂酸 |
| CAS Number | 331-39-5 |
| Molecular Formula | C₉H₈O₄ |
| Molecular Weight | 180.16 g/mol |
| Appearance | Light yellow crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 211–213°C (dec.) |
| Boiling Point | 416.8±40.0 °C (Predicted) |
| Solubility | Slightly soluble in cold water, soluble in hot water, ethanol, methanol and DMSO; insoluble in non-polar solvents |
| Natural Source | Naturally extracted from coffee beans, fruits, vegetables and traditional medicinal herbs, a core active hydroxycinnamic acid in plant polyphenols |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry conditions; avoid high temperature, strong light and air oxidation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Caffeic Acid powder is a high-purity natural hydroxycinnamic acid active ingredient, available in 98% and 99% HPLC grades. Caffeic Acid (CAS 331-39-5), known as 咖啡酸 or 3,4-Dihydroxycinnamic acid, is a prevalent and high-activity plant phenolic acid widely distributed in coffee beans, fresh fruits, vegetables and various medicinal plants. Possessing a unique catechol structure combined with an unsaturated carboxylic acid chain, it delivers stronger antioxidant and anti-inflammatory activity than most conventional phenolic acids. It integrates powerful free radical scavenging, broad-spectrum anti-inflammation, prominent hepatoprotective, antiviral, antibacterial and anti-tumor effects, widely applied in antioxidant anti-aging skincare, liver protection health supplements, functional food additives and advanced biomedical pharmacological research. As a professional bulk Caffeic Acid supplier, we provide high-purity, low-impurity, stable-batch natural phenolic acid raw materials for global industrial and scientific research clients.
Caffeic Acid belongs to the hydroxycinnamic acid family of plant polyphenols, featuring two adjacent hydroxyl groups on the benzene ring, which endows it with superior biochemical activity and structural reactivity. Different from sinapic acid, vanillic acid and protocatechuic acid, Caffeic Acid combines dual core advantages of strong UV resistance and liver protection, with unique antiviral and leukotriene inhibitory properties. Its core functional mechanism activates the Nrf2/ARE endogenous antioxidant pathway, efficiently eliminating intracellular ROS, DPPH and ABTS free radicals, inhibiting lipid peroxidation and oxidative DNA damage. It significantly blocks NF-κB inflammatory cascades, suppresses leukotriene synthesis and pro-inflammatory factor release, relieving acute and chronic inflammation. In pharmacological applications, it resists liver oxidative damage and toxin stimulation, inhibits LDL oxidation, regulates lipid metabolism, and effectively inhibits the proliferation and invasion of malignant tumor cells, with high safety and excellent biocompatibility for long-term topical and oral use.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Caffeic Acid powder adopts low-temperature water-alcohol synergistic extraction and multi-stage high-precision column chromatography purification technology. We select high-quality natural plant raw materials rich in caffeic acid, completely remove plant fibers, macromolecular impurities, residual sugar and invalid pigments through gradient elution purification, and fully retain the complete molecular structure and biological activity of Caffeic Acid. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The mature and stable production process ensures consistent batch purity, uniform light yellow powder appearance and reliable activity stability, meeting the strict formula development and experimental requirements of global customers.
Every batch of Caffeic Acid powder undergoes strict multi-dimensional quality inspection, including HPLC purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished crystalline powder features low impurity content, good solubility in hot water and common organic solvents, stable activity and excellent batch consistency. All products comply with international cosmetic additive regulations, natural functional food safety standards and research-grade compound specifications, supporting safe and standardized application in skincare products, health supplements, functional foods and biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Caffeic Acid supply. Whether you need UV-resistant antioxidant soothing raw materials for skincare formulas, liver-protective and metabolic regulation functional ingredients for health products, or high-purity phenolic acid compounds for anti-inflammatory, antiviral and anti-tumor pharmacological research, our Caffeic Acid powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
Powerful Nrf2 Antioxidant & Anti-Aging (Core Benefit)
Caffeic Acid is a high-activity natural phenolic antioxidant with outstanding free radical scavenging capacity. It specifically activates the Nrf2 endogenous antioxidant defense system, efficiently eliminates multiple reactive oxygen free radicals in the skin and body, inhibits cellular lipid peroxidation and oxidative damage, reduces long-term oxidative stress aging and photoaging, and delivers long-lasting anti-aging and skin rejuvenation effects.
Broad-Spectrum Anti-Inflammatory & Allergy Relief
This natural hydroxycinnamic acid effectively inhibits NF-κB inflammatory pathway activation and leukotriene synthesis, significantly reducing the release of TNF-α, IL-6 and various pro-inflammatory cytokines. It relieves acute inflammatory irritation and chronic low-grade inflammation, calms skin redness, swelling and allergic sensitivity caused by external stimulation, stabilizes skin microecology, and provides mild and efficient soothing and anti-allergy repair effects.
Excellent UV Resistance & Photoprotection
Caffeic Acid has unique ultraviolet absorption properties, which can effectively resist UV-induced oxidative damage and photoinflammation, reduce skin tanning and light aging problems, protect skin barrier function from ultraviolet radiation damage, and is a natural and safe photoprotective active ingredient for outdoor skincare formulas.
Outstanding Hepatoprotective & Lipid Regulation
Modern pharmacological studies verify that Caffeic Acid has prominent liver protective activity. It protects hepatocytes from toxin and oxidative damage, inhibits liver inflammatory infiltration, reduces LDL oxidative modification, optimizes liver lipid metabolism and detoxification functions, repairs mild liver injury, and effectively improves liver sub-health caused by long-term oxidative stress and metabolic disorders.
Broad-Spectrum Antiviral & Antibacterial Activity
Caffeic Acid exerts significant inhibitory effects on a variety of viruses and harmful bacteria. It blocks microbial replication and invasion, reduces microbial-induced inflammatory reactions, assists in maintaining skin and mucosal microbial balance, and achieves green antibacterial and antiviral effects without chemical preservatives.
Anti-Tumor & Immune Regulation
Caffeic Acid can effectively inhibit the proliferation, migration and invasion of malignant tumor cells, induce tumor cell apoptosis, and assist in regulating body immune function. It shows great application potential in auxiliary anti-tumor health care and immune balance conditioning.
Applications
UV Protection & Antioxidant Anti-Aging Skincare
Caffeic Acid is widely used in sunscreen products, anti-photoaging essences, sensitive skin soothing creams and antioxidant repair formulas. It integrates UV resistance, free radical scavenging and anti-inflammatory soothing effects, resists skin light aging and tanning, repairs damaged skin barriers, and is a high-value clean active ingredient for outdoor protection and anti-aging skincare.
Liver Protection & Metabolic Health Supplements
Applied in liver detoxification and liver protection products, lipid metabolism regulation formulas and daily antioxidant health supplements. It protects liver cells, improves lipid metabolism balance, reduces oxidative damage to organs, and provides comprehensive sub-health conditioning for long-term overtime and metabolically disordered groups.
Functional Food & Green Preservation
Used in antioxidant functional foods, nutritional fortified beverages and natural food preservatives. It enhances product antioxidant stability, inhibits microbial growth, delays food oxidative deterioration, extends shelf life, and realizes safe and green nutritional fortification and fresh-keeping effects.
Biomedical & Pharmacological Research
Widely used in Nrf2 antioxidant mechanism research, inflammatory and leukotriene regulation pharmacology, liver protection research, antiviral and anti-tumor pharmacological exploration, serving as a standard high-purity hydroxycinnamic acid research compound for university laboratories and medical research institutions.
Natural Functional Ingredient Innovation
Acts as a core high-activity phenolic acid intermediate for innovative functional product development, supporting the research and iteration of UV-resistant, antioxidant, liver-protective and antiviral natural raw materials.
FAQ
Q1: What is Caffeic Acid powder used for?
A: Caffeic Acid powder is a high-purity natural hydroxycinnamic acid extracted from coffee beans and various plants. It is mainly used for UV-resistant antioxidant skincare, anti-inflammatory soothing repair, liver protection and lipid metabolism regulation, as well as biomedical antiviral and anti-tumor pharmacological research.
Q2: What are the unique advantages of Caffeic Acid?
A: Different from ordinary phenolic acids, Caffeic Acid has exclusive UV photoprotection and strong liver protection activity, with significant antiviral and leukotriene inhibitory effects. It integrates anti-oxidation, anti-inflammation, antibacterial and anti-tumor multi-effects, possessing more comprehensive functional advantages in skincare and health care.
Q3: Is Caffeic Acid safe for cosmetic and food use?
A: Yes, Caffeic Acid is a pure natural plant-derived phenolic acid with mild properties, low irritation and high biocompatibility. It complies with international cosmetic raw material standards and food-grade additive specifications, supporting long-term topical skincare and oral health product application.
Q4: What is the difference between Caffeic Acid and other hydroxycinnamic acids?
A: Compared with sinapic acid and ferulic acid, Caffeic Acid has stronger antioxidant and anti-inflammatory activity, unique ultraviolet absorption capacity and prominent hepatoprotective efficacy, making it more suitable for photoprotective skincare and liver health formula development.
Q5: How to store Caffeic Acid powder correctly?
A: Caffeic Acid powder is sensitive to light, heat and oxidation. It needs to be tightly sealed, protected from light, and stored at 2-8°C in a dry environment. Standard low-temperature and light-proof sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Caffeic Acid samples?
A: Yes, we provide free Caffeic Acid powder samples for skincare formula debugging, functional food development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
