Huperzine A – CAS 102518-79-6 Lycopodium Alkaloid from Huperzia serrata(Qian-ceng-ta)

Huperzine A CAS 102518-79-6

Huperzine A CAS 102518-79-6
1.Nootropic / Study Focus DTC
2.Healthy-Aging Brain R&D
3.Reference Standard (98%+)​

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Huperzine A – CAS 102518-79-6 Lycopodium Alkaloid from Huperzia serrata(Qian-ceng-ta)

Huperzine A – CAS 102518-79-6 Lycopodium Alkaloid from Huperzia serrata(Qian-ceng-ta)

Product Identification

ItemDetail
SynonymsHuperzine A; (–)-Huperzine A; Qian-ceng-ta alkaloid
CAS RN102518-79-6
EC / MDLAvailable on request
Molecular FormulaC₁₅H₁₈N₂O
MW242.32
Alkaloid ClassLycopodium alkaloid (tetracyclic, C₁₅N₂)
Botanical SourceHuperzia serrata(clubmoss), Lycopodiaceae
HS Code (ref)2939 (vegetable alkaloids)
Related (upstream)Huperzia serrata extract 1%–10% HupA; Huperzine B (CAS 103555-74-6, precursor for semi-synth)

Description

Huperzine A is a low-MW Lycopodium alkaloid first isolated from Chinese Huperzia serratain the 1980s, now the most-studied natural AChE inhibitor globally. Two commercial tiers:

  • Extract grade (1% / 5% / 10% HPLC)​ – Huperzia serratawhole-herb extract, tan powder, DTC nootropic brands (“100–200 mcg HupA per capsule”, usually blended with Alpha-GPC / Bacopa / Lion’s Mane / L-tyrosine in “study stack”)
  • Pure CAS 102518-79-6 ≥98% HPLC​ – R&D / pharma pilot / reference standard / premium mono-SKU capsule (100 mcg dose is typical — potency is high, µg not mg)

Four commercial buckets:

  • Nootropic DTC / Study Focus​ – HupA is in the “nootropic Big 5” alongside Alpha-GPC, Bacopa, Lion’s Mane, Galantamine. DTC search clusters: “Huperzine A study focus”, “nootropic stack Huperzine A”, “exam brain supplement”. Exam season (Mar–Jun / Oct–Dec) search pulses in US/EU student demographic. Typical dose 50–200 mcg/capsule (NOT mg — potency high, mis-dosing is a real buyer question).
  • Pharma R&D / AD & Neurodegeneration​ – HupA has been in clinical investigation (AD, vascular dementia, post-stroke cognitive impairment) in CN/US/EU historically; bulk 98%+ feeds CRO/CDMO. Search cluster: “Huperzine A AChE inhibitor AD clinical”, “Lycopodium alkaloid neuro R&D”.
  • Healthy-Aging & BDNF-Adjacent​ – often stacked with Icaritin 118525-40-9 (BDNF) + Quercetin 117-39-5 (senolytic) + CoQ10 303-98-0 (mito)​ in “brain-aging” R&D stacks (claim language restricted, position as “natural Lycopodium alkaloid for cognitive-health R&D”).
  • Reference Standard​ – 98%+ HPLC for Huperziaextract QC, stability, pharmacokinetics.

Applications

Huperzine A – CAS 102518-79-6 | Lycopodium Alkaloid from Huperzia serrata(Qian-ceng-ta)

Nootropic / Study Focus DTC​ – 50–200 mcg/capsule, usually blended “Alpha-GPC + Bacopa + Lion’s Mane + Huperzine A” stack; exam-season pulse traffic

Pharma R&D / AChE Inhibitor Pipeline​ – AD, VaD, post-stroke cognitive; CRO/CDMO bulk 98%+; “Huperzine A clinical” B2B cluster

Healthy-Aging Brain R&D​ – stacked with Icaritin / Quercetin / CoQ10 in “cognitive-aging flavonoid + alkaloid” pilots

Traditional TCM Channel​ – Huperzia serrata(“Qian-ceng-ta”) TCM heritage positioning for CN-export brands

Reference Standard (98%+)​ – for Huperziaextract QC, HPTLC/HPLC quantification

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