Product Introduction
| Item | Specification |
| Product Name | Pterostilbene |
| Synonyms | 3,5-Dimethoxy-4′-hydroxy-trans-stilbene |
| CAS Number | 537-42-8 |
| Molecular Formula | C₁₆H₁₆O₃ |
| Molecular Weight | 256.30 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 89–92°C |
| Boiling Point | 446.8±45.0 °C (Predicted) |
| Solubility | Slightly soluble in water, soluble in ethanol, methanol, DMSO, acetone and organic solvents |
| Natural Source | Naturally extracted from blueberry, red sandalwood and grape plants, a high-activity natural trans-stilbene polyphenol compound |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry conditions; avoid high temperature, strong light and oxidation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Pterostilbene powder is a high-purity natural trans-stilbene active ingredient, available in 98% and 99% HPLC grades. Pterostilbene (CAS 537-42-8), known as or 3,5-dimethoxy-4′-hydroxy-trans-stilbene, is a premium natural polyphenol compound enriched in blueberries and red sandalwood. As a superior methylated derivative of resveratrol, it features a unique dimethoxy substituted stilbene structure, delivering far higher bioavailability, metabolic stability and fat solubility than resveratrol. It integrates ultra-high-efficiency antioxidant, SIRT1-activated anti-aging, tyrosinase-inhibiting whitening, broad-spectrum anti-inflammatory, lipid-lowering hypoglycemic and neuroprotective effects, with outstanding anti-tumor pharmacological activity. Widely applied in high-end anti-aging skincare, longevity health supplements, metabolic conditioning products and advanced biomedical research. As a professional bulk Pterostilbene supplier, we provide high-purity, low-impurity, stable-batch natural stilbene raw materials for global industrial and scientific research clients.
Pterostilbene belongs to the trans-stilbene subclass of natural polyphenols, with a stable conjugated double bond and methoxy modified benzene ring structure. Different from resveratrol and conventional phenolic acids, Pterostilbene has core advantages of stronger stability, higher transdermal absorption and longer biological half-life. Its core functional mechanism targets the SIRT1/AMPK/mTOR longevity signaling pathway, effectively activating cell self-renewal and anti-aging mechanisms, delaying cellular senescence and skin photoaging. It significantly activates the Nrf2 endogenous antioxidant system to scavenge excess ROS free radicals, inhibit lipid peroxidation and oxidative cell damage. In skincare, it specifically blocks tyrosinase activity, inhibits melanin synthesis and UV-induced pigmentation, achieving safe and efficient brightening and whitening effects. In metabolic regulation, it optimizes lipid and glucose metabolism, improves insulin resistance and reduces body inflammation. In pharmacology, it inhibits malignant cell proliferation and invasion, induces tumor cell apoptosis, and exerts significant neuroprotective and cardiovascular protective effects, with ultra-high safety for long-term topical and oral application.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Pterostilbene powder adopts low-temperature bio-enzymatic assisted extraction and multi-stage high-precision column chromatography purification technology. We select high-quality blueberry and red sandalwood plant raw materials with stable active content, completely remove plant fibers, macromolecular impurities, residual sugar and invalid pigments through gradient elution purification, and fully retain the complete trans-stilbene molecular structure and biological activity of Pterostilbene. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The refined purification process solves the problems of low solubility and easy oxidation of natural pterostilbene, ensures uniform powder appearance and stable activity, and meets the strict formula development and experimental requirements of global customers.
Every batch of Pterostilbene powder undergoes strict multi-dimensional quality inspection, including HPLC purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished white crystalline powder features low impurity content, good solubility in common organic solvents, strong stability and excellent batch consistency. All products comply with international cosmetic additive regulations, natural functional food safety standards and research-grade compound specifications, supporting safe and standardized application in high-end skincare products, anti-aging health supplements, functional foods and biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Pterostilbene supply. Whether you need high-efficiency whitening and anti-aging active raw materials for skincare formulas, SIRT1-activated longevity and metabolic conditioning ingredients for health products, or high-purity stilbene compounds for anti-inflammatory, anti-tumor and neuroprotective pharmacological research, our Pterostilbene powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
SIRT1 Activation & Advanced Anti-Aging (Core Benefit)
Pterostilbene is a powerful natural SIRT1 longevity pathway activator, efficiently regulating AMPK/mTOR signaling pathways to promote cell autophagy and repair senescent cells. It delays skin and organ natural aging, improves cellular vitality, and delivers long-lasting anti-aging and anti-senescence effects, being a premium longevity functional ingredient superior to ordinary antioxidants.
Ultra-High Antioxidant & Anti-Photoaging
With stronger free radical scavenging capacity than resveratrol and phenolic acids, Pterostilbene activates the Nrf2 antioxidant defense system, thoroughly eliminates intracellular ROS, inhibits lipid peroxidation and UV-induced oxidative damage, reduces skin light aging, fine lines and dullness, and forms a stable antioxidant protection barrier.
Tyrosinase Inhibition & Brightening Whitening
It specifically inhibits tyrosinase key enzyme activity, blocks the whole melanin synthesis chain, reduces UV-induced tanning and pigment deposition, fades chloasma and dull skin tone. With excellent transdermal permeability and stable whitening efficacy, it achieves mild, non-irritating and long-term skin brightening effects.
Broad-Spectrum Anti-Inflammatory & Skin Repair
Pterostilbene effectively inhibits NF-κB and MAPK inflammatory cascades, reduces the release of TNF-α, IL-6 and multiple pro-inflammatory factors, relieves acute UV inflammation and chronic low-grade skin inflammation, calms redness and sensitivity, and repairs damaged skin barrier function.
Metabolic Regulation & Cardiovascular Protection
Modern pharmacological studies verify that Pterostilbene significantly improves insulin resistance, regulates blood lipid and blood sugar balance, reduces LDL oxidation and vascular inflammatory damage, protects cardiovascular health, and effectively improves sub-health caused by metabolic disorders.
Anti-Tumor & Neuroprotective Activity
Pterostilbene inhibits the proliferation, migration and invasion of various malignant tumor cells, induces tumor cell apoptosis, and exerts broad-spectrum anti-tumor activity. Meanwhile, it protects nerve cells from oxidative stress damage, improves cerebral microcirculation, and delivers excellent neuroprotective effects.
Applications
High-End Anti-Aging & Whitening Skincare
Pterostilbene is widely used in luxury anti-aging essences, brightening whitening serums, anti-photoaging creams and barrier repair skincare products. It integrates SIRT1 anti-aging, free radical scavenging, melanin inhibition and anti-inflammatory soothing multi-effects, effectively improving fine lines, dullness, pigmentation and light aging, being a top-tier clean active ingredient for high-end skincare formula iteration.
Longevity & Metabolic Health Supplements
Applied in cellular anti-aging longevity products, blood sugar and lipid regulation formulas, cardiovascular health care and sub-health conditioning supplements. It activates longevity pathways, optimizes systemic metabolism, enhances body antioxidant capacity, and provides comprehensive anti-aging and metabolic balance conditioning for middle-aged and sub-health groups.
Functional Food & Nutritional Fortification
Used in high-end antioxidant functional foods, nutritional fortified beverages and daily health dietary products. It improves product antioxidant activity, delays food oxidative deterioration, and enhances the nutritional and health value of daily functional foods.
Biomedical & Pharmacological Research
Widely used in SIRT1/AMPK longevity mechanism research, Nrf2 antioxidant pharmacology, metabolic regulation, neuroprotection and anti-tumor mechanism exploration, serving as a standard high-purity trans-stilbene research compound for university laboratories and medical research institutions.
High-End Functional Ingredient Innovation
Acts as a core high-efficiency anti-aging and whitening stilbene intermediate, supporting the research and development of superior natural active ingredients replacing resveratrol, and promoting the innovation of anti-aging and metabolic conditioning functional products.
FAQ
Q1: What is Pterostilbene powder used for?
A: Pterostilbene powder is a high-purity natural trans-stilbene compound extracted from blueberries and red sandalwood. It is mainly used for high-end anti-aging and whitening skincare, cellular longevity health care, blood sugar and lipid metabolic regulation, as well as biomedical anti-inflammatory, neuroprotective and anti-tumor pharmacological research.
Q2: What are the unique advantages of Pterostilbene?
A: Compared with resveratrol and common phenolic acids, Pterostilbene has higher stability, better lipophilicity and 3-5 times higher bioavailability. It features exclusive SIRT1 longevity pathway activation, stronger whitening and anti-aging efficacy, and more prominent metabolic regulation performance, with irreplaceable advantages in high-end functional formulas.
Q3: Is Pterostilbene safe for cosmetic and food use?
A: Yes, Pterostilbene is a pure natural plant-derived active ingredient widely present in edible blueberries and natural plants. It has mild properties, low irritation and high biocompatibility, complying with international cosmetic and food-grade additive standards, supporting long-term topical skincare and oral health product application.
Q4: What is the difference between Pterostilbene and Resveratrol?
A: Pterostilbene is the upgraded methylated derivative of resveratrol. It solves resveratrol’s defects of poor stability and low absorption rate, with stronger antioxidant, whitening and anti-aging activity, longer half-life and better metabolic regulation effects, being a more advanced longevity skincare ingredient.
Q5: How to store Pterostilbene powder correctly?
A: Pterostilbene powder is sensitive to high temperature and strong light. It needs to be tightly sealed, protected from light, and stored at 2-8°C in a dry environment. Standard low-temperature and light-proof sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Pterostilbene samples?
A: Yes, we provide free Pterostilbene powder samples for high-end skincare formula debugging, longevity health product development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
