Product Introduction
| Item | Specification |
| Product Name | Trilobatin |
| Synonyms | p-Phloridzin; Phloretin-4-D-glucoside; 三叶苷 |
| CAS Number | 4192-90-9 |
| Molecular Formula | C₂₁H₂₄O₁₀ |
| Molecular Weight | 436.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 170–172°C |
| Solubility | Soluble in ethanol, methanol, DMSO and hot water; slightly soluble in cold water |
| Natural Source | Naturally extracted from apple leaves, crabapple and pear plants, a rare glycosylated natural dihydrochalcone compound |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at -20°C in sealed condition, away from strong light, heat and moisture; low-temperature storage recommended for long-term preservation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Our Trilobatin powder is a high-purity natural dihydrochalcone active ingredient, available in 98% and 99% HPLC grades. Trilobatin (CAS 4192-90-9), known as 三叶苷, is a unique glycosylated dihydrochalcone predominantly isolated from apple leaves and pomace. Structurally similar to Phloretin, Trilobatin possesses more stable molecular activity and dual skin-beautifying and metabolic regulatory functions, making it a star natural active ingredient in clean skincare and metabolic health product research. It is widely applied in high-end anti-glycation skincare, antioxidant anti-aging formulas, blood sugar regulation supplements and biomedical pharmacological research. As a professional bulk Trilobatin supplier, we provide high-purity, stable-batch and fully compliant products for global industrial and scientific research clients.
Trilobatin belongs to the natural dihydrochalcone family, with superior comprehensive biological activity compared to conventional flavonoids. It integrates high-efficiency anti-oxidation, powerful anti-glycation, broad-spectrum anti-inflammation and natural hypoglycemic effects. In skincare applications, Trilobatin effectively scavenges free radicals, inhibits AGEs glycation reaction, fades skin dullness and yellowish tone, and relieves inflammatory sensitivity, achieving multi-dimensional anti-aging effects including anti-oxidation, anti-glycation and anti-inflammation. In pharmacology and health care fields, Trilobatin optimizes glucose metabolism, improves insulin resistance, inhibits lipid accumulation, and assists in regulating blood sugar and blood lipid levels, showing great potential in improving metabolic syndromes. It also presents mild anti-tumor and neuroprotective activity, with high academic research and industrial application value.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Trilobatin powder adopts low-temperature selective extraction and high-precision column chromatography purification technology. We strictly select fresh apple leaf raw materials to ensure natural and pollution-free sources, remove macromolecular impurities, plant pigments and ineffective components through multi-stage gradient purification, and completely retain the original biological activity of Trilobatin. The whole production process avoids harmful solvent residues and chemical additives, complying with cosmetic-grade, food-grade and research-grade safety standards. The mature and stable production process ensures consistent batch purity, stable solubility and reliable activity, fully meeting the rigorous requirements of high-end formula development and professional laboratory experiments.
Every batch of Trilobatin powder undergoes strict multi-stage quality inspection, including HPLC purity detection, UV spectral verification and NMR structural identification to ensure accurate compound structure and stable purity. The finished pale yellow crystalline powder features uniform color, low impurity content and excellent batch stability. All products comply with international cosmetic safety regulations, natural additive standards and research-grade raw material specifications, supporting safe and standardized application in skincare products, health supplements and biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Trilobatin supply. Whether you need anti-glycation antioxidant raw materials for skincare formulas, metabolic regulation ingredients for functional health products, or high-purity targeted compounds for pharmacological research, our Trilobatin powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
Powerful Anti-Glycation & Brightening (Core Benefit)
Trilobatin is a natural high-efficiency anti-glycation active ingredient, which can significantly inhibit the formation of advanced glycation end products (AGEs) in skin and cells. It blocks skin glycation aging, improves skin yellowish tone, dullness and coarse texture caused by glycation damage, brightens complexion from the source, and restores skin transparency and delicacy, solving endogenous aging problems fundamentally.
High-Efficiency Antioxidant & Anti-Aging
Trilobatin delivers excellent free radical scavenging capacity, effectively eliminating DPPH, ABTS and superoxide anion free radicals. It inhibits cellular lipid peroxidation and oxidative DNA damage, activates the body’s endogenous antioxidant system, delays skin and body aging, resists external oxidative stress damage, and maintains long-term youthful cell vitality.
Broad-Spectrum Anti-Inflammatory & Skin Repair
Trilobatin effectively suppresses the activation of NF-κB inflammatory pathway and reduces the release of various pro-inflammatory cytokines. It relieves acute and chronic skin inflammation, improves redness, sensitivity and barrier damage caused by external irritation, enhances skin tolerance, and stabilizes skin microenvironment, achieving mild and efficient soothing repair effects.
Natural Blood Sugar & Lipid Regulation
As a natural metabolic regulator, Trilobatin optimizes human glucose metabolism, improves insulin resistance, and effectively assists in stabilizing blood sugar levels. It also inhibits adipocyte accumulation and lipid peroxidation, regulates blood lipid balance, relieves metabolic disorders caused by high-sugar and high-fat diets, and improves sub-health metabolic conditions.
Anti-Photoaging & UV Damage Resistance
Trilobatin resists UV-induced oxidative damage and inflammatory reactions, reduces skin sunburn, redness and photoaging symptoms, repairs light-damaged skin barriers, delays skin photoaging, and protects skin from long-term light damage.
Mild Anti-Tumor & Neuroprotective Activity
Modern pharmacological studies confirm that Trilobatin has mild broad-spectrum anti-tumor activity, which can inhibit abnormal proliferation of tumor cells and induce apoptosis. Meanwhile, it exerts neuroprotective effects by reducing oxidative stress damage to nerve cells, providing new research directions for neurological disease auxiliary research.
Applications
High-End Cosmetics & Skincare
Trilobatin is widely used in anti-glycation brightening essences, antioxidant anti-aging serums, soothing repair creams and anti-photoaging skincare products. It targets glycation aging and oxidative aging, effectively improving skin dullness, yellowness and sensitivity, and is a core raw material for high-end anti-aging clean beauty formulas.
Metabolic Regulation & Functional Health Products
Applied in blood sugar regulation health supplements, lipid-lowering functional products and antioxidant anti-aging nutritional formulas. It provides natural and safe metabolic conditioning effects, assisting in improving sub-health problems such as high blood sugar, high blood lipid and obesity.
Biomedical & Scientific Research
Widely used in glycation aging mechanism research, glucose and lipid metabolism research, anti-inflammatory pharmacological experiments, tumor cell biology and neuroprotection research, serving as a standard high-purity research compound for university laboratories and medical research institutions.
Natural Functional Ingredient Development
Acts as a high-value natural dihydrochalcone intermediate for innovative functional product development, supporting the research and iteration of anti-aging, metabolic regulation and anti-inflammatory new raw materials.
Daily Anti-Aging Health Formulations
Used in daily oral anti-aging and antioxidant health products, providing long-term multi-dimensional anti-oxidation, anti-glycation and metabolic protection for the human body.
FAQ
Q1: What is Trilobatin powder used for?
A: Trilobatin powder is a high-activity natural dihydrochalcone compound. It is mainly used for skincare anti-glycation brightening, antioxidant anti-aging and anti-inflammation, body blood sugar and lipid metabolism regulation, and biomedical pharmacological research on aging and metabolism.
Q2: Is Trilobatin safe for cosmetic and oral use?
A: Yes, Trilobatin is a pure natural apple-derived active ingredient with mild properties, no skin irritation and low human toxicity. It complies with international cosmetic and food safety standards, supporting long-term topical skincare application and oral health product addition.
Q3: What are the core advantages of Trilobatin?
A: Trilobatin integrates anti-glycation, anti-oxidation, anti-inflammation and metabolic regulation functions. Compared with ordinary antioxidant ingredients, it targets both oxidative aging and glycation aging, with more comprehensive anti-aging effects and stable molecular activity, featuring unique dual application value in skincare and health care.
Q4: What is the correct storage method for Trilobatin powder?
A: Trilobatin powder is sensitive to light, heat and oxidation. It needs to be tightly sealed and stored at low temperature (-20°C) in a dark and dry environment. Standard sealed low-temperature storage ensures a 24-month valid shelf life.
Q5: Can I get free Trilobatin samples for testing?
A: Yes, we provide free Trilobatin powder samples for skincare formula debugging, health product research and academic pharmacological experiments. Bulk orders support customized purity and packaging to meet diverse production and research needs.
