Product Introduction
| Item | Specification |
| Product Name | p-Coumaric Acid |
| Synonyms | 4-Hydroxycinnamic acid; trans-p-Coumaric acid; |
| CAS Number | 501-98-4 |
| Molecular Formula | C₉H₈O₃ |
| Molecular Weight | 164.16 g/mol |
| Appearance | White crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 210–213°C (dec.) |
| Boiling Point | 328.1±17.0 °C (Predicted) |
| Solubility | Slightly soluble in cold water, soluble in hot water, ethanol, methanol, ether and DMSO; insoluble in non-polar solvents |
| Natural Source | Naturally extracted from grains, tomatoes, carrots, peanuts and common vegetables, the most abundant and active isomer of hydroxycinnamic acid in nature |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry conditions; avoid high temperature, strong light and air oxidation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our p-Coumaric Acid powder is a high-purity natural hydroxycinnamic acid active ingredient, available in 98% and 99% HPLC grades. p-Coumaric Acid (CAS 501-98-4), also known as 4-Hydroxycinnamic is the most prevalent and biologically active monomer among natural hydroxycinnamic acid isomers. It is widely distributed in daily edible plants, grains, fruits and vegetables, featuring a simple and stable para-hydroxy benzene ring structure. Combining powerful antioxidant activity, broad-spectrum anti-inflammation, exclusive UV whitening and photoprotective effects, it also possesses excellent antibacterial, anti-tumor and nitrosamine inhibition properties. It is widely applied in whitening anti-photoaging skincare, functional food anti-oxidation and fresh-keeping, tumor auxiliary health care and advanced biomedical pharmacological research. As a professional bulk p-Coumaric Acid supplier, we provide high-purity, low-impurity, stable-batch natural phenolic acid raw materials for global industrial and scientific research clients.
p-Coumaric Acid belongs to the core subclass of hydroxycinnamic acids, with a single para hydroxyl group on the benzene ring and a complete unsaturated carboxylic acid chain, forming its unique stable biochemical activity and transdermal absorption capacity. Different from caffeic acid and sinapic acid, p-Coumaric Acid has exclusive skin whitening and melanin inhibition core advantages, with superior transdermal permeability and milder skin affinity. Its core functional mechanism activates the Nrf2 endogenous antioxidant pathway to scavenge excess ROS, DPPH and ABTS free radicals, inhibit lipid peroxidation and skin oxidative aging. It effectively blocks NF-κB inflammatory cascade response, reduces pro-inflammatory factor release, and relieves skin photoinflammation and redness. In skincare efficacy, it specifically inhibits melanin synthesis and UV-induced erythema formation, significantly improving skin dullness and pigmentation. In food and pharmacology, it blocks the formation of carcinogenic nitrosamines, inhibits malignant cell proliferation, and exerts significant antibacterial and metabolic regulation effects, with ultra-high safety for long-term topical and oral application.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium p-Coumaric Acid powder adopts low-temperature water-alcohol synergistic extraction and multi-stage high-precision column chromatography purification technology. We select high-quality natural grain and vegetable raw materials rich in p-coumaric acid, completely remove plant fibers, macromolecular impurities, residual sugar and invalid pigment components through gradient elution purification, and fully retain the complete molecular structure and biological activity of p-Coumaric Acid. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The mature and stable production process ensures consistent batch purity, uniform white crystalline powder appearance and reliable activity stability, meeting the strict formula development and experimental requirements of global customers.
Every batch of p-Coumaric Acid powder undergoes strict multi-dimensional quality inspection, including HPLC purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished powder features low impurity content, good solubility in hot water and common organic solvents, stable activity and excellent batch consistency. All products comply with international cosmetic additive regulations, natural functional food safety standards and research-grade compound specifications, supporting safe and standardized application in whitening skincare products, functional foods, health supplements and biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk p-Coumaric Acid supply. Whether you need whitening and anti-photoaging active raw materials for high-end skincare formulas, natural antioxidant and anti-cancer auxiliary ingredients for functional foods, or high-purity hydroxycinnamic acid compounds for antioxidant, anti-inflammatory and tumor pharmacological research, our p-Coumaric Acid powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
Nrf2 Antioxidant & Anti-Aging (Core Benefit)
p-Coumaric Acid is a high-activity natural plant antioxidant. It specifically activates the Nrf2/ARE endogenous antioxidant defense system, efficiently scavenges intracellular reactive oxygen species, DPPH and ABTS free radicals, inhibits cellular lipid peroxidation and oxidative DNA damage, reduces long-term oxidative stress aging, and effectively delays skin and organ natural aging processes.
UV Protection & Professional Skin Whitening
This is the most distinctive advantage of p-Coumaric Acid compared with other phenolic acids. It can effectively absorb ultraviolet rays, resist UV-induced skin photodamage and erythema formation, significantly inhibit melanin synthesis and deposition, improve skin dullness, chloasma and sun tan problems, and deliver safe and mild whitening, brightening and anti-pigmentation effects with verified transdermal whitening efficacy.
Broad-Spectrum Anti-Inflammatory & Skin Soothing
p-Coumaric Acid effectively inhibits NF-κB inflammatory pathway activation, reduces the release of TNF-α, IL-6 and various pro-inflammatory cytokines, relieves acute photoinflammation and chronic low-grade inflammation of the skin, calms redness, sensitivity and irritation caused by UV radiation and external stimulation, and stabilizes skin microecological balance.
Nitrosamine Inhibition & Anti-Tumor Activity
Modern studies verify that p-Coumaric Acid can effectively block the synthesis of carcinogenic nitrosamines in the body, inhibit the proliferation, migration and invasion of malignant tumor cells, induce tumor cell apoptosis, and reduce the risk of digestive tract cancers, showing excellent auxiliary anti-tumor health care value.
Broad-Spectrum Antibacterial & Food Preservation
p-Coumaric Acid exerts significant inhibitory effects on common food spoilage bacteria and harmful microorganisms. It delays food oxidative deterioration and microbial reproduction, extends the shelf life of functional foods and beverages, and achieves green, safe and non-residual fresh-keeping and antibacterial effects.
Metabolic Regulation & Body Anti-Oxidation Conditioning
It optimizes systemic oxidative metabolism, reduces tissue inflammatory oxidative damage, assists in regulating lipid and sugar metabolism balance, improves sub-health caused by long-term oxidative stress, and enhances overall body antioxidant capacity and immune stability.
Applications
Whitening & Anti-Photoaging Skincare
p-Coumaric Acid is widely used in whitening essence, brightening skincare products, sunscreen formulas, post-sun repair creams and anti-pigmentation skincare. It integrates UV protection, free radical scavenging, anti-photoinflammation and melanin inhibition effects, effectively improves sun tan and dull skin, and is a premium clean whitening active ingredient for high-end light anti-aging skincare.
Functional Food & Green Preservation
Applied in antioxidant functional foods, grain nutritional fortification products, beverages and natural preservatives. It inhibits nitrosamine formation, prevents food oxidation and deterioration, extends product shelf life, and improves the nutritional and health value of daily foods.
Anti-Tumor & Metabolic Health Supplements
Used in digestive tract health care products, anti-oxidation anti-aging supplements and metabolic conditioning functional products. It assists in inhibiting harmful carcinogen formation, regulates body oxidative balance, and provides long-term mild health conditioning for sub-health groups.
Biomedical & Pharmacological Research
Widely used in Nrf2 antioxidant mechanism research, UV photoprotection and melanin regulation research, nitrosamine inhibition and anti-tumor pharmacological exploration, serving as a standard high-purity hydroxycinnamic acid research compound for university laboratories and medical research institutions.
Natural Functional Ingredient Innovation
Acts as a core whitening and anti-photoaging phenolic acid intermediate for innovative functional product development, supporting the research and iteration of natural whitening, sunscreen, antioxidant and anti-tumor raw materials.
FAQ
Q1: What is p-Coumaric Acid powder used for?
A: p-Coumaric Acid powder is a high-purity natural hydroxycinnamic acid extracted from grains and vegetables. It is mainly used for skin whitening, UV protection and anti-photoaging skincare, green food preservation, anti-tumor auxiliary health care, as well as biomedical antioxidant and inflammatory pharmacological research.
Q2: What are the unique advantages of p-Coumaric Acid?
A: Different from caffeic acid and other phenolic acids, p-Coumaric Acid has exclusive natural whitening and UV anti-pigmentation efficacy, with excellent transdermal absorption and nitrosamine inhibition ability. It combines skincare whitening, antioxidant and anti-cancer auxiliary effects, with more targeted advantages in beauty and health product development.
Q3: Is p-Coumaric Acid safe for cosmetic and food use?
A: Yes, p-Coumaric Acid is a pure natural plant-derived phenolic acid, widely present in daily edible grains and vegetables. It features mild properties, low irritation and high biocompatibility, complying with international cosmetic and food-grade additive standards, supporting long-term topical and oral application.
Q4: What is the difference between p-Coumaric Acid and other hydroxycinnamic acids?
A: Caffeic acid focuses on liver protection and UV resistance, sinapic acid focuses on metabolic regulation and anti-tumor, while p-Coumaric Acid is specialized in skin whitening and anti-pigmentation, being the best natural phenolic acid raw material for whitening and sunscreen formula development.
Q5: How to store p-Coumaric Acid powder correctly?
A: p-Coumaric Acid powder is sensitive to light, heat and oxidation. It needs to be tightly sealed, protected from light, and stored at 2-8°C in a dry environment. Standard low-temperature and light-proof sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free p-Coumaric Acid samples?
A: Yes, we provide free p-Coumaric Acid powder samples for skincare formula debugging, functional food development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
