Rutin NF11 – CAS 90131-19-4 | Sophora japonica Flower Bud Extract (USP-NF Grade)
Product Identification
| Item | Detail |
|---|---|
| Synonyms | Rutin NF11; Sophora japonica extract (Rutin std.); Fagopyrum esculentumRutin (alternative source, specify); Quercetin-3-O-rutinoside |
| CAS RN (extract grade) | 90131-19-4 |
| CAS RN (marker, pure) | 153-18-8 |
| Molecular Formula (pure rutin) | C₂₇H₃₀O₁₆ |
| MW (pure rutin) | 610.52 |
| Botanical | Sophora japonicaL., Fabaceae (flower buds) |
| HS Code (ref) | 1302 (vegetable extracts) / 2938 (flavonoids) |
| Standard Followed | USP-NF “Rutin” monograph (NF11 specification) |
Description
Rutin (quercetin-3-O-rutinoside) is a flavonol glycoside widely distributed in Sophora japonica(flower buds), buckwheat, and rue. The NF11 grade from Sophora japonicabuds is the dominant export form to EU/US pharma & nutra channels, conforming to USP-NF limits on heavy metals, solvent residues, and microbials.
Four commercial buckets drive search & procurement:
- Venotonic / Microcirulation – often combined with Diosmin + Hesperidin in European venotonic formulas (chronic venous insufficiency, hemorrhoidal flare, capillary fragility); rutin’s antioxidant & MMP-modulating activity supports vein-wall integrity
- Cardiovascular & Cerebrovascular (pharma China channel) – rutin injection (ChP) line for cerebral infarction adjunctive; NF11 extract is the upstream material
- Antioxidant & Food/Beverage – natural flavonoid, water solubility better than quercetin (rutinoside sugar helps); functional beverages, bakery, nutraceutical blends
- Cosmeceutical – anti-glycation, soothing, often paired with vitamin C / niacinamide / centella in JP/EU skin-care
Applications
Venotonic & Microcirculation Supplements – chronic venous insufficiency, capillary fragility, hemorrhoid support; commonly blended Diosmin + Hesperidin + Rutin (European formula archetype)
Pharmaceutical (China export) – upstream for rutin injection (ChP cerebrovascular adjunct), oral tablet grade; NF11 meets USP-NF monograph
Nutraceuticals & Functional Beverages – antioxidant flavonoid blend, often with vitamin C, quercetin, hesperidin
Cosmetics – anti-glycation, soothing, barrier-supportive; INCI Rutin(if purified sub-grade)
Feed & Pet – capillary/antioxidant supportive (niche)