Product Introduction
| Item | Specification |
| Product Name | Paraxanthine |
| Synonyms | 1,7-Dimethylxanthine; p-Xanthine; 3,7-Dihydro-1,7-dimethyl-1H-purine-2,6-dione |
| CAS Number | 611-59-6 |
| Molecular Formula | C₇H₈N₄O₂ |
| Molecular Weight | 180.16 g/mol |
| Appearance | White fine crystalline powder, odorless, stable crystal form under sealed dark and dry conditions |
| Purity (HPLC) | ≥98.0% / ≥99.0% (Research Grade / Premium Grade, customizable) |
| Loss on Drying | ≤ 0.2% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / NMR / Mass Spectrometry / IR Spectrum / Biological Activity Detection |
| Production Method | Biological Metabolic Simulation & High-Purity Chemical Synthesis & Multi-Stage Recrystallization Purification |
| Melting Point | 294–296°C (lit.) |
| Boiling Point | 313.0°C at 760 mmHg (Predicted) |
| Density | 1.60 g/cm³ at 25°C |
| Flash Point | 9.0°C |
| Solubility | Slightly soluble in water, soluble in hot water, methanol, ethanol and DMSO; insoluble in chloroform; stable in neutral and dry environments |
| Core Feature | Key caffeine metabolite, unique 1,7-dimethylxanthine structure, mild CNS stimulant with superior lipolytic and neuroprotective activity |
| Package | 1g/5g/10g sealed amber bottle, 100g/1kg drum; vacuum moisture-proof & light-proof packaging, custom specification available |
| Storage | Store in vacuum-sealed, low-temperature, dark and dry conditions; avoid high temperature, humid environment and prolonged light exposure to prevent activity attenuation |
| Shelf Life | 24 months under standard low-temperature sealed and dark storage |
Product Description
Our Paraxanthine (CAS 611-59-6), chemically defined as 1,7-Dimethylxanthine, is a high-purity natural methylxanthine alkaloid and the primary active metabolite of caffeine in the human body. Supplied in premium research grade and industrial high-purity grade, this compound features a unique dimethyl-substituted purine skeleton, distinguishing it from caffeine and theobromine with differentiated pharmacological properties. As the most abundant and bioactive metabolite generated during caffeine metabolism, Paraxanthine retains mild central nervous system excitatory effects while exhibiting stronger lipolytic, neuroprotective and anti-inflammatory activities, with significantly lower cardiovascular stimulatory side effects. It has become a core research compound in metabolic pharmacology, neuroscience, sports nutrition and natural functional ingredient development. As a professional bulk Paraxanthine supplier, we provide low-impurity, high-activity, batch-stable 1,7-Dimethylxanthine raw materials for global scientific research institutions, pharmaceutical laboratories and functional food manufacturing enterprises.
Paraxanthine occupies a unique research status in the methylxanthine family, with irreplaceable advantages in physiological regulation and metabolic mechanism research. Unlike caffeine, which causes strong central excitement and heart rate elevation, Paraxanthine delivers mild, stable and safe physiological regulation. Its core pharmacological mechanisms include adenosine receptor antagonism and phosphodiesterase inhibition, which effectively promote fat decomposition and energy metabolism, enhance neural excitability without causing nervous overstimulation, and improve cognitive function and mental alertness. In addition, Paraxanthine exerts significant neuroprotective effects by reducing neuronal oxidative stress and inflammatory damage, helping to maintain central nervous system stability. It also regulates lipid metabolism and improves energy utilization efficiency, supporting extensive research on fat metabolism, exercise endurance and metabolic disorder intervention. Our high-purity Paraxanthine eliminates isomer impurities, residual synthesis intermediates and mixed xanthine contaminants, ensuring single-component purity and stable biological activity, which guarantees accurate and repeatable experimental data for high-precision pharmacological research and product development.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Paraxanthine adopts advanced bionic metabolic synthesis combined with multi-stage gradient purification and low-temperature recrystallization refining technology. The whole production process strictly controls reaction parameters and purification gradients, effectively removing trace catalysts, organic residues and isomer impurities generated during synthesis. The closed dust-free and light-shielded production system avoids molecular oxidation and structural degradation, completely retaining the complete 1,7-dimethylxanthine active skeleton and inherent physiological activity. The finished product presents uniform white fine crystalline powder with stable crystal form, no caking, no discoloration and no deterioration, fully complying with international research-grade and high-purity functional ingredient quality standards.
Every batch of Paraxanthine undergoes strict multi-dimensional quality inspection, including HPLC high-precision purity analysis, NMR structural verification, mass spectrometry molecular identification and biological activity stability testing. It achieves ultra-low impurity residue and zero invalid interference, ensuring consistent batch efficacy and excellent experimental repeatability. The product features stable solubility in common organic solvents and good biochemical compatibility in cell culture and in vivo animal experiment environments, fully meeting the strict raw material requirements of caffeine metabolism research, neural regulation mechanism exploration, lipid metabolism experiments and functional ingredient efficacy verification.
We maintain sufficient low-temperature light-proof inventory and complete qualification documents for bulk Paraxanthine supply. Whether you need standard methylxanthine monomer tools for basic metabolic pharmacology research, positive control reagents for neuroprotective and lipolytic efficacy tests, or high-purity raw materials for functional food and nutritional product development, our premium Paraxanthine is a high-cost-performance and high-value choice for global buyers.
Functions & Benefits
Mild & Safe CNS Regulation (Core Benefit)
As a major caffeine metabolite, Paraxanthine provides mild central nervous system excitation, effectively improving mental alertness and cognitive performance without causing jitteriness, tachycardia or anxiety. It is safer and more stable than caffeine for long-term physiological regulation research.
Powerful Lipolytic & Metabolic Regulatory Activity
Paraxanthine significantly promotes lipolysis and fat energy metabolism, accelerates lipid decomposition and energy release, and improves body energy utilization efficiency. It serves as a core tool compound for fat metabolism and weight management mechanism research.
Excellent Neuroprotective & Anti-Inflammatory Effects
High-purity Paraxanthine scavenges intracellular reactive oxygen species, reduces neuronal oxidative stress and neuroinflammatory damage, protects nerve cell activity, and stabilizes central nervous system function, supporting neurological protection and brain health research.
Unique 1,7-Dimethylxanthine Structural Specificity
With exclusive 1,7-dimethyl substitution on the purine ring, Paraxanthine possesses differentiated pharmacological activity compared with theobromine and caffeine. Its unique molecular structure provides key templates for methylxanthine structure-activity relationship research and new drug derivative development.
High Single-Component Purity & Zero Impurity Interference
Our Paraxanthine adopts full-process high-precision purification technology, completely eliminating xanthine isomer impurities and synthesis by-products. It ensures pure monomer activity, zero experimental interference and consistent batch pharmacological efficacy.
Stable Biocompatibility & Wide Application Adaptability
Paraxanthine has stable solubility in conventional experimental solvents and excellent biochemical compatibility. It maintains stable biological activity in cell and animal experiments, perfectly adapting to metabolic pharmacology, neuroscience and functional product development research.
Applications
Caffeine Metabolism & Metabolic Pharmacology Research
Used as a standard metabolite reference reagent for studying human caffeine metabolic pathways, xanthine compound physiological transformation and energy metabolism regulation mechanisms, widely applied in metabolic pharmacology laboratories.
Neurological & Cognitive Function Research
Served as the core experimental compound for exploring neuroprotection, cognitive improvement, central nerve excitation regulation and neuroinflammatory repair, supporting brain health and neural physiological mechanism research.
Lipid Metabolism & Sports Nutrition Research
Applied in fat decomposition mechanism research, exercise energy metabolism regulation and weight management efficacy verification, providing core raw materials for the development of safe metabolic regulation functional ingredients.
Methylxanthine Structure-Activity Relationship Study
Used as a typical 1,7-dimethylxanthine model compound to compare the activity differences of caffeine, theobromine and paraxanthine, enriching the medicinal chemistry theoretical system of methylxanthine alkaloids.
Laboratory Teaching & Pharmacological Demonstration
Provided as standard high-purity Paraxanthine reagent for natural alkaloid teaching experiments, caffeine metabolism pathway demonstration and xanthine pharmacological activity comparison tests, ensuring accurate and stable experimental data for scientific research and teaching.
FAQ
Q1: What is Paraxanthine mainly used for?
A: Paraxanthine is a key active caffeine metabolite and methylxanthine alkaloid. It is mainly used for caffeine metabolism mechanism research, neural cognitive regulation study, lipid metabolism and lipolysis research, neuroprotective experiments and functional ingredient development.
Q2: What is the difference between Paraxanthine and Caffeine?
A: Paraxanthine is the primary metabolite of caffeine in vivo. It features milder central stimulation, no obvious cardiovascular side effects, and stronger lipolytic and neuroprotective activities, with higher safety and better metabolic regulation performance than caffeine.
Q3: What are the core advantages of our Paraxanthine?
A: Our Paraxanthine adopts professional multi-stage recrystallization purification technology, featuring ultra-high single-component purity, zero xanthine isomer and synthesis impurity interference, stable lipolytic and neuroprotective activity, and consistent batch quality for high-precision pharmacological research.
Q4: How to store Paraxanthine correctly?
A: Paraxanthine is sensitive to high temperature, humidity and strong light, prone to activity attenuation. It must be stored in vacuum-sealed, low-temperature, light-proof and dry dark conditions. Standard sealed low-temperature dark storage ensures 24 months of stable shelf life and biological activity.
Q5: What is the appearance of high-purity Paraxanthine?
A: High-purity Paraxanthine is uniform white fine crystalline powder at room temperature, odorless, stable crystal state, no caking, no fading and no deterioration.
Q6: Can I get free Paraxanthine samples for testing?
A: Yes, we provide free Paraxanthine samples for metabolic mechanism research, neuroprotective efficacy verification and functional ingredient development experiments. Bulk orders support customized purity and professional light-proof vacuum packaging to meet scientific research and industrial production needs.
