Jaceosidin CAS 18085-97-7 6-Methoxyluteolin Flavone from Artemisia/ Centaurea
Product Identification
| Item | Detail |
|---|---|
| Synonyms | Jaceosidin; 6-Methoxyluteolin; 5,7,3′,4′-Tetrahydroxy-6-methoxyflavone; Cirsilineol (some lit conflation — Cirsilineol = 3′,4′,5,6,7-pentaOH-3-OMe? Actually Cirsilineol = 3′,4′,5,6,7-pentaOH-3-OMe = 3-OMe instead of 6-OMe, diff compound — PO clarify if lit search mixes) |
| CAS RN | 18085-97-7 |
| Parent (aglycone upstream) | Luteolin CAS 491-70-3 (5,7,3′,4′-tetraOH flavone, C₁₅H₁₀O₆) — Jaceosidin = Luteolin-6-OMe |
| Molecular Formula | C₁₇H₁₄O₇ |
| MW | 330.29 |
| Botanical (main) | Artemisia argyi(艾蒿, neuro+GI crossover), A. capillaris(茵陈, hepatic/ChP “Yin-Chen”) — both Asteraceae |
| Botanical (name-origin) | Centaurea/ Centratherum(Asteraceae, “棕矢车菊”) |
| Same-genus siblings | Artemisinin 63968-64-9 (A. annua, sesquiterpene lactone) + Eupatilin 22368-21-4 (A. argyi, PMF) — “Artemisia triple-SKU” |
| HS Code (ref) | 1302 / 2938 |
Description
Jaceosidin is the 6-methoxy derivative of Luteolin from Artemisia / Centaurea— the flavone-OMe node of the Artemisiatriple-skeleton cluster (alongside Artemisinin-lactone / Eupatilin-PMF).
Applications
Neuro / Aβ R&D – Jaceosidin ≥98% Aβ₁₋₄₂/ROS/NF-κB/BACE1 SH-SY5Y PC12; 6-OMe vs Luteolin parent (lipophilic↑ BBB↑); inner-link “OMe-flavone neuro cluster”: Luteolin(parent) + Wogonin(C8-OMe Scutellaria) + Jaceosidin(C6-OMe Artemisia); Neuro 、
Hepatic / Artemisia capillarisYin-Chen – A. capillarisP.E. Jaceosidin 1–5% + Luteolin% (Yin-Chen grade); NAFLD/CCl₄/D-GalN lit ALT/AST↓ TGF-β1↓; “liver botanical” cluster Silymarin/Curcumin/Schisandraif in SKU; DTC: “Artemisia capillaris traditional Yin-Chen liver-supportive”soft
Anti-allergy / Skin (minor) – Jaceosidin RBL-2H3 histamine↓ β-hex↓ COX-2↓; A. argyimoxa traditional skin/warmth crossover; KR “moxa-botanical” niche minor
Reference Standard (≥98%) – for ArtemisiaP.E. QC (Jaceosidin% + Luteolin% + optionally Eupatilin% if A. argyimulti-skeleton), neuro/hepatic R&D
