| Item | Specification |
| Product Name | Helichrysetin |
| Synonyms | 4,2′,4′-Trihydroxy-6′-methoxychalcone; Helichrysetin; Wax chrysanthemum extract |
| CAS Number | 62014-87-3 |
| Molecular Formula | C₁₆H₁₄O₅ |
| Molecular Weight | 286.28 g/mol |
| Appearance | Yellow crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 220°C (decomposition) |
| Solubility | Soluble in ethanol, methanol, DMSO and acetone; slightly soluble in hot water; insoluble in cold water |
| Natural Source | Naturally extracted from Helichrysum odoratissimum flowers and Alpinia katsumadai fruits, a rare bioactive natural chalcone compound |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store in a cool, dry place; keep tightly sealed and protected from light, heat and moisture |
| Shelf Life | 24 months when stored properly in original packaging |
Product Description
Our Helichrysetin powder is a high-purity natural chalcone compound, available in 98% and 99% HPLC grades. Helichrysetin (CAS 62014-87-3), also known as wax chrysanthemum extract, is a rare bioactive ingredient isolated from Helichrysum odoratissimum flowers and Alpinia katsumadai fruits. It is well-known for its powerful antioxidant, anti-inflammatory, anti-proliferative and anti-tumor properties, widely applied in biomedical research, skincare functional formulas and natural active ingredient development. As a professional bulk Helichrysetin supplier, we provide high-purity, stable-batch products for global research and industrial clients.
Helichrysetin belongs to the natural chalcone family, featuring a unique chemical structure and multi-target biological activity that distinguishes it from conventional plant flavonoids. As a potent ID2 inhibitor, it can effectively regulate cell cycle progression, induce abnormal cell apoptosis, and inhibit cell proliferation and metastasis. Meanwhile, it delivers excellent free radical scavenging capacity and anti-inflammatory effects, effectively relieving oxidative stress and chronic inflammation. With high biological activity and stable chemical properties, Helichrysetin has become a hotspot compound in modern pharmacology and clean beauty research fields.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Helichrysetin powder adopts low-temperature selective extraction and high-precision column chromatography purification technology. We strictly select natural plant raw materials to remove impurities, fully retain the original biological activity of the chalcone compound, and avoid harmful solvent residues throughout the production process. All production procedures comply with international raw material processing standards, ensuring low impurity content, high purity and consistent batch stability, meeting the strict requirements of laboratory research and high-end formula development.
Every batch of Helichrysetin powder undergoes rigorous multi-stage quality inspection, including HPLC purity detection, UV spectral verification and NMR structural identification. The finished products feature stable quality, controllable impurities and reliable biological activity. They comply with global research-grade raw material and cosmetic safety standards, supporting safe application in biomedical experiments, anti-tumor research, antioxidant skincare and functional ingredient development.
We maintain sufficient inventory and complete qualification documents for bulk Helichrysetin supply. Whether you need raw materials for scientific pharmacological research, anti-tumor mechanism study, antioxidant anti-inflammatory skincare formulas or natural functional product development, our high-purity Helichrysetin powder is a cost-effective and reliable bulk raw material choice.
Functions & Benefits
Potent Anti-Tumor & Anti-Proliferative Activity (Core Benefit)
Helichrysetin serves as an effective ID2 inhibitor, which can significantly inhibit the proliferation of various tumor cells, block cell cycle progression, and induce cancer cell apoptosis. It suppresses tumor angiogenesis and cell metastasis, showing broad-spectrum anti-tumor activity against multiple cancer types. With low toxicity to normal cells, it has high research value for tumor prevention and auxiliary treatment.
High-Efficiency Antioxidant & Anti-Aging
Helichrysetin delivers excellent free radical scavenging capacity, effectively eliminating excess reactive oxygen species in cells and inhibiting lipid peroxidation. It reduces oxidative stress damage to cell DNA and membranes, delays cellular aging, improves skin oxidative dullness, and maintains youthful cell vitality and skin elasticity.
Significant Anti-Inflammatory Effects
Helichrysetin effectively inhibits the release of pro-inflammatory cytokines and blocks chronic inflammatory signaling pathways. It relieves persistent low-grade inflammation in the body and skin, reduces inflammatory lesion progression, alleviates skin redness and sensitivity, and stabilizes skin and internal microenvironment balance.
Cell Cycle Regulation & Apoptosis Induction
As a key research bioactive compound, Helichrysetin can precisely regulate cell cycle distribution, arrest abnormal cell division, and promote apoptosis of damaged and cancerous cells. It provides important experimental support for cell biology research and pathological mechanism exploration.
Skin Protection & Skincare Anti-Oxidation
In skincare applications, Helichrysetin resists external oxidative damage and environmental stress, repairs mild inflammatory skin damage, improves skin dullness and roughness, and enhances skin barrier stability. Its mild and efficient antioxidant properties make it suitable for high-end anti-aging and soothing skincare formulas.
Anti-Viral Research Activity
Modern pharmacological studies confirm that Helichrysetin has mild anti-HIV protease activity, possessing potential research value in anti-viral drug development and related biomedical mechanism research, expanding its application in innovative pharmaceutical research.
Applications
Biomedical & Scientific Research
Helichrysetin is widely used in tumor pharmacological research, cell cycle mechanism studies, anti-tumor drug screening and antiviral experiments, serving as a standard high-purity research compound for university laboratories and medical research institutions.
Cosmetics & Anti-Aging Skincare
Applied in antioxidant essences, anti-aging skincare products, soothing repair formulas and sensitive skin care products, providing efficient anti-oxidation, anti-inflammation and skin stabilizing effects for high-end clean beauty products.
Pharmaceutical Intermediate Development
Used as a core raw material for new anti-tumor and anti-inflammatory drug development, serving as a key pharmaceutical intermediate for innovative biomedical and targeted therapeutic preparations.
Natural Functional Ingredient Development
Applied in the research and development of high-value natural chalcone active ingredients, used for functional screening of anti-oxidation, anti-inflammation and anti-tumor raw materials for health products.
Health Product Research
Used in the development of antioxidant and anti-inflammatory health formula prototypes, providing natural and safe active raw materials for functional health product innovation and research.
FAQ
Q1: What is Helichrysetin powder used for?
A: Helichrysetin powder is a high-activity natural chalcone compound. It is mainly used for biomedical anti-tumor research, cell cycle regulation, antioxidant anti-inflammation, and high-end skincare anti-aging formula development.
Q2: Is Helichrysetin safe for skincare use?
A: Yes, it is a natural plant-derived active ingredient with mild properties, high safety and no skin irritation. It complies with global cosmetic safety standards and is suitable for adding to soothing and anti-aging skincare formulas.
Q3: What are the core advantages of Helichrysetin?
A: Helichrysetin integrates anti-tumor, antioxidant and anti-inflammatory activities. As a rare natural chalcone and ID2 inhibitor, it has stronger targeted biological activity and higher research value than conventional plant extracts, with stable formula compatibility.
Q4: How should Helichrysetin be stored?
A: Helichrysetin powder is sensitive to light and high temperature. It needs tight sealing and storage in a cool, dry and dark environment. The standard shelf life is 24 months under proper storage conditions.
Q5: Can I get free Helichrysetin samples?
A: Yes, we provide free Helichrysetin powder samples for laboratory research, formula testing and academic experiments. Bulk orders support customized purity and packaging to meet diverse research and production needs.
