Product Introduction
| Item | Specification |
| Product Name | Narirutin |
| Synonyms | Naringenin-7-O-rutinoside; Isonaring |
| CAS Number | 14259-46-2 |
| Molecular Formula | C₂₇H₃₂O₁₄ |
| Molecular Weight | 580.53 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 162–164°C |
| Boiling Point | 924.3±65.0 °C (Predicted) |
| Solubility | Soluble in water, ethanol, methanol and DMSO; excellent water solubility, widely compatible with water-based formulas |
| Natural Source | Naturally extracted from citrus fruits such as mandarin, orange and grapefruit, a characteristic water-soluble flavonoid rutinoside in Rutaceae plants |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at -20°C in sealed, dark and dry conditions; avoid high temperature, strong light and oxidation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Narirutin powder is a high-purity natural water-soluble citrus flavonoid glycoside active ingredient, available in 98% and 99% HPLC grades. Narirutin (CAS 14259-46-2), commonly known as, is a premium rutinoside monomer compound isolated from fresh citrus fruits including mandarin, orange and grapefruit. Structurally, it is the 7-O-rutinoside derivative of Naringenin, retaining the core flavanone activity while binding rutinoside glycosyl groups, which endows it with excellent water solubility that fat-soluble citrus flavonoids lack. It integrates powerful water-soluble antioxidant, broad-spectrum anti-inflammatory, anti-allergic, lipid metabolism regulating and hepatoprotective effects, widely applied in water-based soothing skincare, sensitive skin repair, metabolic health supplements and biomedical pharmacological research. As a professional bulk Narirutin supplier, we provide high-purity, stable-batch and fully compliant products for global industrial and scientific research clients.
Narirutin belongs to the flavonoid rutinoside subclass, featuring a stable molecular structure with both flavanone parent nucleus and rutinoside sugar chain. This unique structure gives it dual advantages of high biological activity and excellent water solubility, perfectly making up for the poor water solubility of Naringenin (fat-soluble aglycone). Its core functional mechanism activates the Nrf2/ARE endogenous antioxidant pathway and inhibits NF-κB inflammatory signaling cascade, efficiently scavenging intracellular reactive oxygen species, reducing oxidative stress damage, and suppressing the release of multiple pro-inflammatory cytokines such as TNF-α and IL-6. Different from Naringin, Narirutin has milder activity and better skin compatibility, with outstanding anti-allergic and airway soothing effects. In pharmacological applications, it also exerts significant lipid-lowering, liver-protective, antibacterial and anti-proliferative activity, with ultra-high safety and no toxic side effects for long-term oral and topical use.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Narirutin powder adopts low-temperature water-alcohol synergistic extraction and multi-stage high-precision column chromatography purification technology. We select high-quality fresh citrus fruit raw materials with stable active content, completely remove fruit sugars, plant fibers, macromolecular impurities and invalid components through gradient elution purification, and fully retain the complete glycoside active structure and biological activity of Narirutin. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The mature and stable production process ensures consistent batch purity, uniform powder appearance and reliable activity stability, meeting the strict formula development and experimental requirements of global customers.
Every batch of Narirutin powder undergoes strict multi-dimensional quality inspection, including HPLC purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished white crystalline powder features low impurity content, excellent water solubility and organic solvent compatibility, and outstanding batch consistency. All products comply with international cosmetic additive regulations, natural functional ingredient safety standards and research-grade compound specifications, supporting safe and standardized application in skincare products, functional beverages, health supplements and biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Narirutin supply. Whether you need water-soluble anti-inflammatory and anti-allergy raw materials for skincare formulas, mild lipid-regulating and liver-protective ingredients for health products, or high-purity citrus rutinoside compounds for oxidative stress, inflammation and immunological pharmacological research, our Narirutin powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
Water-Soluble Nrf2 Antioxidant & Anti-Aging (Core Benefit)
Narirutin is a high-efficiency water-soluble natural citrus antioxidant. It specifically activates the Nrf2/ARE antioxidant signaling pathway, efficiently scavenges DPPH, ABTS and intracellular reactive oxygen free radicals, inhibits cellular lipid peroxidation and oxidative DNA damage, enhances endogenous antioxidant defense capacity, and delays skin and systemic aging caused by long-term oxidative stress. Its superior water solubility ensures uniform dispersion and stable efficacy in water-based formulas.
Broad-Spectrum Anti-Inflammatory & Anti-Allergic Soothing
This natural citrus flavonoid glycoside effectively inhibits NF-κB inflammatory pathway activation, reduces the release of multiple pro-inflammatory factors, and relieves acute and chronic low-grade inflammation. It delivers prominent anti-allergic activity, effectively improving allergic skin reactions, redness, swelling and itching, and alleviating airway inflammatory irritation. With ultra-mild properties, it stabilizes skin and mucosal microecology, ideal for sensitive and fragile skin care.
Lipid Metabolism Regulation & Cardiovascular Protection
Modern pharmacological studies verify that Narirutin can inhibit abnormal lipid synthesis and peroxidation, reduce triglyceride and cholesterol levels, improve lipid metabolism disorders caused by high-fat diets, inhibit vascular lipid deposition, and assist in maintaining cardiovascular health, providing mild and long-term metabolic conditioning effects.
Hepatoprotective & Detoxification Effects
Narirutin protects liver parenchymal cells from oxidative damage and toxic stimulation, inhibits liver inflammatory infiltration and fat accumulation, optimizes liver detoxification and metabolic functions, repairs mild liver damage, and effectively improves liver sub-health conditions caused by oxidative stress and metabolic disorders.
Broad-Spectrum Antibacterial & Immunomodulatory Activity
Narirutin exerts significant inhibitory effects on common pathogenic bacteria, effectively reducing microbial-induced inflammatory damage. It regulates body immune response, improves allergic inflammatory symptoms, enhances mucosal immune defense capacity, and delivers comprehensive protective effects on skin and respiratory tract health.
Sensitive Skin Barrier Repair & Stabilization
With excellent water solubility and skin affinity, Narirutin penetrates and repairs damaged skin barriers, reduces moisture loss, relieves dryness, sensitivity and redness caused by external irritation, stabilizes fragile skin condition, and improves skin tolerance for long-term gentle maintenance.
Applications
Water-Based Sensitive Skin Skincare Products
Narirutin is widely used in soothing repair toners, anti-allergy essences, sensitive skin lotions and water-based antioxidant skincare formulas. It features outstanding water solubility, gently calms skin inflammation and redness, repairs damaged barriers, resists oxidative aging, and is a high-value mild functional ingredient for clean sensitive beauty.
Metabolic & Liver Protection Health Supplements
Applied in lipid regulation nutritional formulas, liver protection detox supplements, cardiovascular health products and allergic constitution conditioning products. It optimizes body lipid metabolism, protects liver and vascular health, relieves chronic inflammation, and provides mild and safe daily sub-health conditioning.
Water-Based Functional Food & Beverages
As a safe water-soluble citrus flavonoid, Narirutin is widely used in functional beverages, nutritional fortified drinks, liquid health products and dietary supplements. It improves product antioxidant and anti-inflammatory efficacy with good water compatibility and no peculiar smell, enhancing product nutritional value and stability.
Biomedical & Scientific Research
Widely used in Nrf2 antioxidant mechanism research, inflammatory immunology, lipid metabolism regulation, liver protection pharmacodynamics and anti-allergy pharmacological studies, serving as a standard high-purity citrus rutinoside research compound for university laboratories and medical research institutions.
Natural Water-Soluble Functional Ingredient Innovation
Acts as a high-value water-soluble citrus flavonoid intermediate for innovative functional product development, supporting the research and iteration of soothing, anti-allergy, antioxidant and metabolic regulation natural raw materials.
FAQ
Q1: What is Narirutin powder used for?
A: Narirutin (Narirutin powder) is a high-purity water-soluble citrus flavonoid glycoside extracted from citrus fruits. It is mainly used for sensitive skin soothing, anti-allergy and antioxidant skincare, body lipid metabolism regulation and liver protection, as well as biomedical anti-inflammation and immunomodulatory pharmacological research.
Q2: What is the difference between Narirutin, Naringenin and Naringin?
A: Naringenin is fat-soluble aglycone with high cell permeability; Naringin is naringenoside with ordinary water solubility; Narirutin is rutinoside with excellent water solubility, milder anti-allergy and soothing effects, most suitable for water-based formulas and sensitive skin products.
Q3: Is Narirutin safe for long-term use?
A: Yes, Narirutin is a pure natural citrus-derived active ingredient with ultra-mild properties, zero irritation and high biocompatibility. It complies with international cosmetic raw material standards and food-grade safety specifications, supporting long-term topical skincare and oral health product application.
Q4: What are the core advantages of Narirutin?
A: Narirutin features excellent water solubility and superior skin tolerance, with unique mild anti-allergy and anti-inflammatory effects. It integrates anti-oxidation, lipid-lowering and liver-protective multi-effects, perfectly suitable for water-based formula development and sensitive skin scenario applications.
Q5: How to store Narirutin powder correctly?
A: Narirutin powder is sensitive to high temperature, strong light and oxidation. It needs to be tightly sealed and stored at -20°C in a dark and dry environment. Standard low-temperature sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Narirutin samples?
A: Yes, we provide free Narirutin powder samples for skincare formula debugging, functional beverage development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
