Swertiamarin (CAS 17388-39-5) – High-Purity Iridoid Glucoside from Swertia Herb

Production Introduction
Swertiamarin is a naturally occurring iridoid glucoside isolated from the aerial parts of Swertiaspecies (Gentianaceae). It presents as a white to off-white crystalline powder, slightly hygroscopic, with a distinctly bitter taste. As a classic Traditional Chinese Herbal Extract component, it has long been used for cholagogue, stomachic, antispasmodic and analgesic purposes in phytomedicine.
Our Swertiamarin is supplied at ≥96% / ≥98% HPLC, suitable for pharmaceutical R&D, natural health product formulation, cosmetic antioxidant systems, and botanical reference standard use.
Specifications
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98% (also available ≥96%) |
| Melting Point | 111–114 °C |
| Specific Rotation | -127° (c=1, 96% ethanol) |
| Solubility | Soluble in MeOH, EtOH, water; insoluble in CHCl₃, pet ether |
| Molecular Formula | C₁₆H₂₂O₁₀ |
| Molecular Weight | 374.34 |
| CAS No. | 17388-39-5 |
| Storage | 2–8 °C, sealed, dark, dry |
| Shelf Life | 2 years |
Applications

Pharmaceutical R&D / Active Pharmaceutical Intermediate (API intermediate) – studied for antispasmodic, analgesic, cholagogue, anti-inflammatory pathways
Herbal Extract & Phytomedicine – ingredient in digestive health and liver-support TCM formulas
Cosmetic & Personal Care – antioxidant / soothing botanical actives (formulation dependent)
Reference Standard / Research – HPLC qualification, pharmacological screening, content determinatiPharmaceutical R&D / Active Pharmaceutical Intermediate (API intermediate) – studied for antispasmodic, analgesic, cholagogue, anti-inflammatory pathways
Why Choose Our Swertiamarin CAS 17388-39-5
Batch-level COA & HPLC chromatogram provided
Stable supply from Swertiacultivated source, kg-scale available
Double sealed, moisture-proof packaging (aluminum foil + desiccant)
FAQ
Q: Is Swertiamarin the same as sweroside?
A: No. Both are iridoid glucosides from Swertia/Gentianafamily, but different aglycones and CAS numbers. Swertiamarin = CAS 17388-39-5.
Q: What solvent should I use for dissolution?
A: Methanol, ethanol or DMSO are recommended; poorly soluble in chloroform and petroleum ether.
Q: Can you provide a Certificate of Analysis?
A: Yes — every batch ships with COA (HPLC purity, heavy metals, solvents residue on request).




