Product Introduction
| Item | Specification |
| Product Name | Sulfapyridine |
| Synonyms | 4-Amino-N-(pyridin-2-yl)benzenesulfonamide; 2-Sulfanilamidopyridine |
| CAS Number | 144-83-2 |
| Molecular Formula | C₁₁H₁₁N₃O₂S |
| Molecular Weight | 249.29 g/mol |
| Appearance | White to off-white crystalline powder, odorless, stable crystal morphology at room temperature |
| Purity (HPLC/GC) | ≥98.0% / ≥99.0% (Pharma Grade / Research Grade, customizable) |
| Loss on Drying | ≤ 0.2% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / GC / NMR / Mass Spectrometry / IR Spectrum |
| Production Method | Precision Condensation Synthesis & Multi-Stage Recrystallization Purification & Impurity Removal |
| Melting Point | 191–193°C (lit.) |
| Boiling Point | 473.5°C at 760 mmHg |
| Density | 1.4 g/cm³ at 25°C |
| Flash Point | 240.1°C |
| Solubility | Slightly soluble in water, soluble in ethanol, methanol, DMSO and polar organic solvents, stable in neutral and weakly acidic reaction systems |
| Core Feature | Stable benzenesulfonamide-pyridine fused skeleton, specific antibacterial inhibitory activity, high sulfonamide derivatization reaction activity |
| Package | 10g/100g sealed amber bottle, 1kg/5kg drum; custom packaging available |
| Storage | Store in sealed, cool, dark and dry conditions; avoid high temperature, strong light and humid environment to prevent oxidation and structural degradation |
| Shelf Life | 24 months under standard sealed storage |
Product Description
Our Sulfapyridine is a high-purity pharmaceutical-grade sulfonamide heterocyclic intermediate with stable molecular structure and excellent biological activity, available in 98% and 99% premium grades. Sulfapyridine (CAS 144-83-2) is a classic pyridine-containing sulfonamide compound in the fields of fine chemical synthesis and biomedical pharmacology. Different from terpenoid products such as Borneol and Terpinen-4-ol focused on fragrance and antisepsis, and differentiated from conventional pyridine monomers such as Pyridoxine used for nutritional and metabolic research, Sulfapyridine is professionally positioned in antibacterial pharmacological research, sulfonamide derivative synthesis and pharmaceutical intermediate customization, featuring a unique integrated benzenesulfonamide-pyridine skeleton and specific bacterial enzyme inhibitory activity. As a professional bulk Sulfapyridine supplier, we provide low-impurity, high-activity, batch-stable sulfonamide raw materials for global biomedical research institutions, pharmaceutical R&D enterprises and fine chemical synthesis factories.
Sulfapyridine occupies an important core position in sulfonamide antibiotic research and heterocyclic derivative industry. As a typical structural prototype of pyridine sulfonamide compounds, it can competitively inhibit bacterial dihydropteroate synthetase, blocking bacterial folic acid synthesis and producing significant broad-spectrum bacteriostatic effects. In fine chemical synthesis, its stable dual-ring conjugated structure provides abundant active modification sites, supporting structural optimization, functional group substitution and derivative development of various sulfonamide drugs. Compared with ordinary industrial-grade Sulfapyridine with high impurity content and unstable activity, our high-purity purified product eliminates unreacted raw materials, isomer residues and inorganic impurities, ensuring single-component purity and ultra-stable experimental repeatability and synthesis applicability.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Sulfapyridine adopts advanced precision condensation synthesis technology combined with multi-stage low-temperature recrystallization and high-precision gradient impurity removal process. The whole production process is carried out under strict constant temperature and inert environment protection, effectively avoiding molecular oxidation, structural distortion and by-product generation. We strictly control reaction proportion, pH value and purification parameters to completely remove trace solvent residues, intermediate impurities and invalid structural isomers, retaining the complete and active sulfonamide-pyridine skeleton of Sulfapyridine. The finished product presents uniform white crystalline powder, no caking, no discoloration, stable physical and chemical properties, fully complying with pharmaceutical intermediate grade and high-precision scientific research grade quality standards.
Every batch of Sulfapyridine undergoes strict multi-dimensional quality inspection, including HPLC high-precision purity analysis, NMR structural verification, mass spectrometry molecular identification and trace impurity residue detection. It ensures ultra-high single-component purity, zero invalid impurity interference and consistent batch quality, providing reliable raw material guarantee for antibacterial mechanism research and sulfonamide derivative synthesis. The product features moderate solvent solubility, excellent reaction stability in mild environments and high derivatization conversion rate, fully meeting the strict raw material requirements of pharmacological testing, new drug development and custom fine chemical synthesis.
We maintain sufficient inventory and complete qualification documents for bulk Sulfapyridine supply. Whether you need standard active monomers for antibacterial biomedical research, core intermediates for sulfonamide derivative customization, or high-purity raw materials for pharmaceutical formula debugging, our pharmaceutical-grade Sulfapyridine is a high-cost-performance and high-value fine chemical product choice for global buyers.
Functions & Benefits
Specific Bacterial Enzyme Inhibitory Activity (Core Benefit)
Sulfapyridine has typical sulfonamide bacteriostatic properties, which can specifically inhibit bacterial dihydropteroate synthetase, interfere with bacterial folic acid metabolism and cell synthesis, and produce efficient broad-spectrum antibacterial effects. It is a standard tool compound for studying bacterial drug resistance and antibacterial mechanism pathways.
High-Activity Sulfonamide Heterocyclic Intermediate
With stable benzenesulfonamide-pyridine dual-ring skeleton and multiple active functional groups, Sulfapyridine has excellent structural modification and derivatization potential. It supports custom synthesis and structural optimization of various sulfonamide antibacterial derivatives, with controllable reaction process and high finished product yield.
Professional Pharmacological Research Standard Compound
High-purity Sulfapyridine features stable biological activity and single-component purity, serving as a key experimental monomer for antibacterial pharmacology, drug resistance mechanism research and sulfonamide drug efficacy evaluation. It ensures high accuracy and repeatability of biomedical experimental data.
Ultra-Low Impurity & Stable Structural Stability
Pharmaceutical-grade purified Sulfapyridine removes heavy metal residues, organic impurities and structural isomer interference. It has stable chemical properties, no adverse impact on downstream synthesis reactions and biological experiments, effectively ensuring the purity and activity consistency of derived products.
Strict Batch Consistency & Industrial Adaptability
Synthetic and recrystallized Sulfapyridine avoids raw material quality fluctuations and seasonal differences. The product has stable crystal form and uniform activity, suitable for long-term continuous industrial derivative production and high-precision laboratory scientific research projects.
Excellent Solubility & Reaction Compatibility
Sulfapyridine has good solubility in common polar organic solvents and stable activity in neutral and weakly acidic systems. It is easy to dissolve and compound, with high modification reaction efficiency, perfectly adapting to various pharmaceutical synthesis and formula debugging scenarios.
Applications
Antibacterial Biomedical & Pharmacological Research
Used as a standard high-purity sulfonamide monomer for studying bacterial metabolic inhibition mechanism, antibacterial drug resistance and sulfonamide pharmacological activity. Widely applied in university laboratories, pharmaceutical research institutes and microbial pharmacology testing institutions.
Sulfonamide Derivative Custom Synthesis
Served as the core skeleton intermediate for structural modification and functional derivatization of pyridine sulfonamide compounds, supporting the R&D of new high-efficiency antibacterial drugs, pharmaceutical intermediates and biological active molecules.
Pharmaceutical Intermediate Manufacturing
Applied in the production and upgrading of sulfonamide pharmaceutical raw materials, used for formula optimization and intermediate preparation of antibacterial preparations, meeting pharmaceutical-grade raw material quality standards.
Microbial & Biochemical Experiment Debugging
Used for microbial inhibition experiments, antibacterial spectrum testing and biochemical pathway verification, providing accurate and stable raw material support for microbial research and biochemical mechanism exploration.
Laboratory Scientific Research & New Product Development
Provided as standard high-purity Sulfapyridine monomer for structural activity verification, synthetic process debugging and custom experimental development, supporting pharmaceutical innovation and fine chemical product iteration.
FAQ
Q1: What is Sulfapyridine mainly used for?
A: Sulfapyridine is a high-value sulfonamide heterocyclic pharmaceutical intermediate. It is mainly used for antibacterial pharmacological mechanism research, sulfonamide derivative custom synthesis, pharmaceutical intermediate manufacturing and microbial biochemical experiments, with stable bacteriostatic activity and excellent derivatization performance.
Q2: What makes Sulfapyridine different from common sulfonamide products?
A: Sulfapyridine has a unique pyridine-fused sulfonamide dual-ring structure, which endows it with stronger targeted bacterial enzyme inhibitory activity and higher structural modification potential. Different from single-structure sulfonamides, it has both pharmacological research value and industrial synthesis value, with more stable activity and wider application scenarios.
Q3: What are the core advantages of our Sulfapyridine?
A: Our Sulfapyridine adopts pharmaceutical-grade condensation synthesis and multi-stage recrystallization purification technology. It features ultra-high single-component purity, ultra-low trace impurities, stable molecular structure and consistent batch activity. It can effectively improve the accuracy of pharmacological experiments and the yield of derivative synthesis, with outstanding industrial and scientific research advantages.
Q4: How to store Sulfapyridine correctly?
A: Sulfapyridine is sensitive to strong light, high temperature and humid environment, prone to oxidation and activity attenuation. It needs to be stored in sealed, cool, dry and dark conditions. Standard sealed storage ensures 24 months of stable shelf life and biological activity.
Q5: What is the appearance of high-purity Sulfapyridine?
A: High-purity Sulfapyridine is uniform white to off-white crystalline powder at room temperature, odorless, stable crystal state, no caking, no discoloration and no visible impurity precipitation.
Q6: Can I get free Sulfapyridine samples for testing?
A: Yes, we provide free Sulfapyridine samples for antibacterial experiment verification, synthetic process debugging and derivative development tests. Bulk orders support customized purity and packaging to meet industrial production and scientific research needs.
