Product Introduction
| Item | Specification |
| Product Name | Naringenin |
| Synonyms | 4′,5,7-Trihydroxyflavanone; Naringetol; |
| CAS Number | 480-41-1 |
| Molecular Formula | C₁₅H₁₂O₅ |
| Molecular Weight | 272.25 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 252–254°C |
| Boiling Point | 577.2±50.0 °C (Predicted) |
| Solubility | Soluble in ethanol, methanol, DMSO and alkaline solutions; slightly soluble in hot water; insoluble in cold water and most neutral organic solvents |
| Natural Source | Naturally extracted from citrus fruits, mainly grapefruit, orange and lemon, a core bioactive flavanone monomer in citrus plants |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at -20°C in sealed, dark and dry conditions; avoid high temperature, strong light and oxidation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Naringenin powder is a high-purity natural citrus flavanone active ingredient, available in 98% and 99% HPLC grades. Naringenin (CAS 480-41-1), commonly known as , is a premium bioactive monomer compound isolated from natural citrus fruits such as grapefruit and sweet orange. As the aglycone form of Naringin, it features higher cell permeability and biological activity than glycoside-type citrus flavonoids, with a stable 4′,5,7-trihydroxyflavanone molecular structure. It integrates powerful Nrf2 antioxidant, broad-spectrum anti-inflammatory, lipid metabolism regulation, liver protection and broad-spectrum antibacterial effects, widely applied in antioxidant anti-aging skincare, metabolic health supplements, liver protection products and biomedical pharmacological research. As a professional bulk Naringenin supplier, we provide high-purity, stable-batch and fully compliant products for global industrial and scientific research clients.
Naringenin belongs to the dihydroflavanone subclass of flavonoids, with three hydroxyl active groups on the parent nucleus, granting it excellent free radical scavenging capacity and biochemical activity. Its core functional mechanism relies on activating the Nrf2/HO-1 endogenous antioxidant pathway and inhibiting the NF-κB inflammatory cascade, efficiently removing excess reactive oxygen species in the body, reducing oxidative stress damage, and blocking the release of multiple pro-inflammatory cytokines. Compared with Naringin (naringoside), Naringenin is fat-soluble with stronger transdermal absorption and cell penetration capabilities, making it more suitable for high-efficiency skincare formulas and in-vivo pharmacological interventions. In metabolic regulation, it significantly inhibits lipid peroxidation and cholesterol synthesis, reduces blood lipid levels, and improves fat accumulation and metabolic disorders. It also exerts significant hepatoprotective, antiviral and antibacterial activity, with mild properties and no toxic side effects for long-term application.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Naringenin powder adopts low-temperature selective solvent extraction and multi-stage high-precision column chromatography purification technology. We select high-quality fresh citrus fruit raw materials with stable active content, completely remove fruit sugars, plant fibers, macromolecular impurities and invalid components through gradient elution purification, and fully retain the pure monomer structure and complete biological activity of Naringenin. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The mature and stable production process ensures consistent batch purity, uniform powder appearance and reliable activity stability, meeting the strict formula development and experimental requirements of global customers.
Every batch of Naringenin powder undergoes strict multi-dimensional quality inspection, including HPLC purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished white crystalline powder features low impurity content, good solubility in organic solvents and alkaline solutions, and outstanding batch consistency. All products comply with international cosmetic additive regulations, natural functional ingredient safety standards and research-grade compound specifications, supporting safe and standardized application in skincare products, health supplements, functional foods and biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Naringenin supply. Whether you need high-efficiency antioxidant anti-aging raw materials for skincare formulas, lipid-lowering and liver-protective ingredients for metabolic health products, or high-purity citrus flavanone compounds for oxidative stress, inflammation and metabolic pharmacological research, our Naringenin powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
High-Efficiency Nrf2 Antioxidant & Anti-Aging (Core Benefit)
Naringenin is a classic high-activity natural citrus antioxidant. It specifically activates the Nrf2/HO-1 antioxidant signaling pathway, efficiently scavenges DPPH, ABTS and intracellular reactive oxygen free radicals, inhibits cellular lipid peroxidation and oxidative DNA damage, enhances endogenous antioxidant defense capacity, and comprehensively delays skin and systemic aging caused by long-term oxidative stress.
Broad-Spectrum Anti-Inflammatory & Soothing Relief
This natural flavanone effectively inhibits the activation of NF-κB and MAPK inflammatory pathways, significantly reducing the release of TNF-α, IL-6 and other pro-inflammatory factors. It relieves acute and chronic low-grade inflammation in the body, calms skin redness, swelling and sensitivity caused by external stimuli, stabilizes skin microecology, and delivers mild and durable soothing repair effects.
Lipid Metabolism Regulation & Anti-Atherosclerosis
Modern pharmacological studies verify that Naringenin can inhibit liver cholesterol and triglyceride synthesis, reduce blood lipid levels, improve lipid metabolism disorders caused by high-fat diets, inhibit lipid deposition and vascular plaque formation, and effectively assist in improving hyperlipidemia and vascular sub-health.
Hepatoprotective & Detoxification Enhancement
Naringenin protects liver parenchymal cells from oxidative damage and toxic stimulation, inhibits liver inflammatory infiltration and fat accumulation, optimizes liver detoxification and metabolic functions, repairs damaged liver tissues, and is a safe and effective natural liver-protective active ingredient.
Broad-Spectrum Antibacterial & Antiviral Activity
Naringenin exerts significant inhibitory effects on multiple common pathogenic bacteria such as Staphylococcus aureus and Escherichia coli. It also has broad-spectrum antiviral potential, inhibits viral replication and invasion, reduces microbial-induced inflammatory damage, and enhances body immune defense capacity.
Skin Barrier Repair & UV Damage Relief
With excellent cell permeability, Naringenin penetrates the skin to scavenge deep free radicals, relieve oxidative damage and inflammatory irritation caused by UV radiation and environmental pollution, repair damaged skin barriers, reduce skin dullness and aging signs, and restore healthy and tender skin condition.
Applications
High-Efficiency Antioxidant Anti-Aging Skincare
Naringenin is widely used in high-end anti-aging essences, antioxidant repair creams, post-sun repair products and sensitive soothing formulas. It features strong transdermal absorption capacity, scavenges deep skin free radicals, relieves inflammatory sensitivity, repairs light-damaged skin, and is a high-value natural active ingredient for advanced anti-aging skincare.
Metabolic & Liver Protection Health Supplements
Applied in blood lipid regulation formulas, liver protection detox supplements, cardiovascular health products and metabolic sub-health conditioning products. It optimizes lipid metabolism, protects vascular and liver health, improves body microcirculation, and provides long-term mild health conditioning for sub-health groups.
Functional Food & Nutritional Fortification
As a safe natural flavanone, Naringenin is used in functional health foods, nutritional fortified products and daily dietary supplements. It enhances product antioxidant, lipid-regulating and antibacterial preservation efficacy, improving overall nutritional value and product stability.
Biomedical & Scientific Research
Widely used in Nrf2 antioxidant mechanism research, inflammatory pharmacology, lipid metabolism regulation, liver protection pharmacodynamics and antiviral activity studies, serving as a standard high-purity citrus flavanone research compound for university laboratories and medical research institutions.
Natural Functional Ingredient Innovation
Acts as a high-value citrus flavanone intermediate for innovative functional product development, supporting the research and iteration of antioxidant, anti-inflammatory, lipid-lowering and liver-protective natural raw materials.
FAQ
Q1: What is Naringenin powder used for?
A: Naringenin (Naringenin powder) is a high-purity natural citrus flavanone extracted from grapefruit and citrus fruits. It is mainly used for high-efficiency antioxidant anti-aging and skin repair, body blood lipid regulation and metabolic conditioning, liver protection and detoxification, as well as biomedical anti-inflammation, antibacterial and antiviral pharmacological research.
Q2: What is the difference between Naringenin and Naringin?
A: Naringenin is the fat-soluble aglycone monomer with strong cell permeability and higher biological activity, suitable for high-efficiency skincare and in-vivo intervention; Naringin is the water-soluble glycoside form with better water solubility, suitable for water-based formulas and oral beverages. The two have complementary application scenarios.
Q3: Is Naringenin safe for cosmetic and health product use?
A: Yes, Naringenin is a pure natural citrus-derived active ingredient with mild properties, low irritation and high biocompatibility. It complies with international cosmetic raw material standards and food-grade safety specifications, supporting long-term topical skincare and oral health product application.
Q4: What are the core advantages of Naringenin?
A: Naringenin has excellent cell permeability and bioavailability, far exceeding glycoside flavonoids. It integrates anti-oxidation, anti-inflammation, lipid-lowering, liver protection and antibacterial multi-effects, with stable molecular activity and wide application in high-end formula development and biomedical research.
Q5: How to store Naringenin powder correctly?
A: Naringenin powder is sensitive to high temperature, strong light and oxidation. It needs to be tightly sealed and stored at -20°C in a dark and dry environment. Standard low-temperature sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Naringenin samples?
A: Yes, we provide free Naringenin powder samples for skincare formula debugging, functional food development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
