Product Introduction
| Item | Specification |
| Product Name | Sinapic Acid |
| Synonyms | Sinapinic acid; 4-Hydroxy-3,5-dimethoxycinnamic acid |
| CAS Number | 530-59-6 |
| Molecular Formula | C₁₁H₁₂O₅ |
| Molecular Weight | 224.21 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 203–205°C (dec.) |
| Boiling Point | 403.4±40.0 °C (Predicted) |
| Solubility | Soluble in hot ethanol, methanol, DMSO and organic solvents; slightly soluble in cold water; insoluble in petroleum ether |
| Natural Source | Naturally extracted from cruciferous plants, rapeseed and grains, a high-activity hydroxycinnamic acid phenolic monomer |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry conditions; avoid high temperature, strong light and oxidation (light-sensitive) |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Sinapic Acid powder is a high-purity natural hydroxycinnamic acid active ingredient, available in 98% and 99% HPLC grades. Sinapic Acid (CAS 530-59-6), also known as Sinapinic acid or , is a premium natural phenolic acid monomer widely present in cruciferous vegetables, rapeseed and cereal plants. Featuring a unique 3,5-dimethoxy-4-hydroxycinnamic acid molecular structure, it possesses more stable antioxidant activity and richer pharmacological functions than conventional phenolic acids. It integrates high-efficiency free radical scavenging, broad-spectrum anti-inflammation, hypoglycemic and lipid-lowering, anti-tumor and neuroprotective effects, widely applied in antioxidant skincare, metabolic health supplements, functional food development and advanced biomedical scientific research. As a professional bulk Sinapic Acid supplier, we provide high-purity, low-impurity, light-stable and batch-consistent natural phenolic acid raw materials for global industrial and scientific research clients.
Sinapic Acid belongs to the hydroxycinnamic acid subclass of phenolic compounds, with dual methoxy and hydroxyl active groups on the benzene ring, forming its unique high biochemical activity and structural stability. Different from protocatechuic acid and vanillic acid, Sinapic Acid has outstanding dual advantages of metabolic regulation and anti-tumor pharmacological activity. Its core mechanism activates the Nrf2/ARE antioxidant pathway to eliminate intracellular ROS, inhibit lipid peroxidation and oxidative cell damage. It significantly blocks NF-κB and MAPK inflammatory cascades, reducing the release of TNF-α, IL-6 and pro-inflammatory factors to relieve chronic inflammation. In metabolic regulation, it inhibits ACE-I and HDAC activity, effectively improving insulin resistance, lowering blood sugar and blood lipid levels, and correcting metabolic disorders. In biomedical research, it induces tumor cell apoptosis, inhibits the proliferation of malignant cells, and shows great potential in anti-cancer and auxiliary anti-tumor applications, with high safety and no toxic side effects for long-term use.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Sinapic Acid powder adopts low-temperature selective solvent extraction and multi-stage high-precision column chromatography purification technology. We select high-quality natural cruciferous plant and rapeseed raw materials with stable active content, completely remove plant fibers, macromolecular impurities, residual sugar and invalid pigments through gradient elution purification, and fully retain the complete molecular structure and biological activity of Sinapic Acid. The entire production process avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. Considering the product’s light-sensitive characteristics, we adopt fully enclosed dark production and packaging processes to ensure stable activity and no degradation. The mature production process guarantees consistent batch purity, uniform powder appearance and reliable efficacy stability, meeting strict formula development and experimental requirements of global customers.
Every batch of Sinapic Acid powder undergoes strict multi-dimensional quality inspection, including HPLC purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished white crystalline powder features low impurity content, good solubility in common organic solvents, stable activity and excellent batch consistency. All products comply with international cosmetic additive regulations, natural functional food safety standards and research-grade compound specifications, supporting safe and standardized application in skincare products, health supplements, functional foods and biomedical research projects. It is also widely used as a high-quality MALDI mass spectrometry matrix for peptide and protein analysis in scientific laboratories.
We maintain sufficient inventory and complete qualification documents for bulk Sinapic Acid supply. Whether you need natural antioxidant soothing raw materials for skincare formulas, metabolic regulation and anti-aging functional ingredients for health products, or high-purity phenolic acid compounds for anti-inflammatory, anti-tumor and metabolic pharmacological research, our Sinapic Acid powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
High-Efficiency Nrf2 Antioxidant & Anti-Aging (Core Benefit)
Sinapic Acid is a high-activity natural phenolic antioxidant with powerful free radical scavenging capacity. It specifically activates the Nrf2 endogenous antioxidant defense system, efficiently eliminates DPPH, ABTS and intracellular reactive oxygen species, inhibits cellular lipid peroxidation and oxidative DNA damage, reduces long-term oxidative stress damage to skin and organs, and effectively delays natural aging and photoaging processes.
Broad-Spectrum Anti-Inflammatory & Skin Soothing
This natural hydroxycinnamic acid effectively inhibits NF-κB and MAPK inflammatory pathway activation, significantly reducing the release of various pro-inflammatory cytokines. It relieves acute inflammatory irritation and chronic low-grade inflammation in the body, calms skin redness, swelling and sensitivity caused by external stimulation and oxidative damage, stabilizes skin microecology, and provides mild and efficient soothing repair effects for fragile skin.
Hypoglycemic & Lipid-Regulating Metabolic Protection
Modern pharmacological studies verify that Sinapic Acid has significant metabolic regulation activity. It inhibits ACE-I and HDAC activity, improves insulin resistance, enhances glucose tolerance, reduces serum total cholesterol and triglyceride levels, and effectively improves hyperglycemia, hyperlipidemia and metabolic syndrome, providing natural and mild metabolic balancing effects.
Unique Anti-Tumor & Cell Protection Activity
As a rare phenolic acid with anti-tumor efficacy, Sinapic Acid can effectively induce apoptosis of malignant tumor cells, inhibit the proliferation of various cancer cells, and block tumor cell invasion and metastasis. It shows excellent application potential in auxiliary anti-tumor health care and biomedical anti-cancer research fields.
Neuroprotective & Antioxidative Neuro-Care
Sinapic Acid protects nerve cells from oxidative damage and inflammatory stress, improves cerebral microcirculation, reduces neuronal apoptosis, and relieves brain oxidative fatigue. It maintains nervous system stability and delivers mild and effective neuroprotective effects for sub-health groups with long-term brain fatigue.
Green Antibacterial & Formula Stabilization
Sinapic Acid exerts mild broad-spectrum antibacterial activity against common harmful microorganisms, inhibiting bacterial reproduction and microbial-induced inflammation. It improves product stability, delays oxidative deterioration, and can be used as a safe green preservative and stabilizer for functional formulas.
Applications
Antioxidant Soothing & Anti-Aging Skincare
Sinapic Acid is widely used in high-end antioxidant anti-aging essences, sensitive skin soothing creams, post-sun repair formulas and barrier maintenance skincare products. It scavenges deep skin free radicals, relieves inflammatory sensitivity, resists light aging, repairs damaged skin barriers, and is a high-value clean natural active ingredient for functional skincare formulation.
Metabolic & Anti-Aging Health Supplements
Applied in blood sugar and lipid regulation formulas, metabolic syndrome conditioning products, cardiovascular health supplements and anti-aging health care products. It optimizes glucose and lipid metabolism, improves insulin sensitivity, protects vascular health, and provides comprehensive sub-health conditioning for obese and metabolically disordered groups.
Biomedical & Tumor Pharmacological Research
Widely used in HDAC and ACE-I inhibitor research, tumor cell apoptosis mechanism exploration, Nrf2 antioxidant pathway pharmacology and neuroprotective research. It serves as a standard high-purity hydroxycinnamic acid compound for university laboratories and medical research institutions, and is commonly used as a high-quality MALDI mass spectrometry matrix for biomolecular analysis.
Functional Food & Nutritional Fortification
Used in antioxidant functional foods, nutritional fortified beverages and daily health dietary supplements. It enhances product antioxidant and metabolic regulation efficacy, improves food stability and shelf life, and realizes green and safe nutritional fortification.
Natural Functional Ingredient Innovation
Acts as a core high-activity hydroxycinnamic acid intermediate for innovative functional product development, supporting the research and iteration of antioxidant, anti-inflammatory, metabolic regulating and anti-tumor natural raw materials.
FAQ
Q1: What is Sinapic Acid powder used for?
A: Sinapic Acid powder is a high-purity natural hydroxycinnamic acid extracted from cruciferous plants and grains. It is mainly used for antioxidant soothing skincare, blood sugar & lipid metabolic regulation, anti-tumor and neuroprotective health care, as well as biomedical pharmacological research and mass spectrometry matrix applications.
Q2: What are the unique advantages of Sinapic Acid?
A: Different from ordinary phenolic acids, Sinapic Acid has dual core advantages of metabolic regulation and anti-tumor activity, with strong HDAC and ACE-I inhibitory effects. It integrates anti-oxidation, anti-inflammation, neuroprotection and lipid-lowering efficacy, showing more comprehensive pharmacological value than conventional phenolic acid monomers.
Q3: Is Sinapic Acid safe for cosmetic and food use?
A: Yes, Sinapic Acid is a pure natural plant-derived phenolic acid with mild properties, low irritation and high biocompatibility. It complies with international cosmetic raw material standards and food-grade additive specifications, supporting long-term topical skincare and oral health product application.
Q4: What is the difference between Sinapic Acid and other phenolic acids?
A: Most common phenolic acids focus on basic anti-oxidation and anti-inflammation. Sinapic Acid features unique hypoglycemic, lipid-lowering and anti-tumor pharmacological activities, with stable molecular structure and higher biological activity, occupying an irreplaceable position in high-end functional formula and biomedical research.
Q5: How to store Sinapic Acid powder correctly?
A: Sinapic Acid powder is light-sensitive and susceptible to oxidation. It needs to be tightly sealed, protected from light, and stored at 2-8°C in a dry environment. Standard low-temperature and light-proof sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Sinapic Acid samples?
A: Yes, we provide free Sinapic Acid powder samples for skincare formula debugging, functional food development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
