Product Introduction
| Item | Specification |
| Product Name | Luteolin |
| Synonyms | 3′,4′,5,7-Tetrahydroxyflavone; Luteolin Flavonoid Monomer; Natural Luteolin Powder |
| CAS Number | 491-70-3 |
| Molecular Formula | C₁₅H₁₀O₆ |
| Molecular Weight | 286.24 g/mol |
| Appearance | Light yellow crystalline fine powder, odorless, uniform crystal texture, no caking, no impurities or discoloration under standard sealed storage conditions |
| Purity (HPLC) | Luteolin ≥98.0% / ≥99.0% (Research Grade / Premium Functional Grade, customizable) |
| Melting Point | 328–330°C (lit.) |
| Loss on Drying | ≤ 0.2% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / NMR / Mass Spectrometry / IR Spectrum / Biological Activity Assay |
| Production Method | Natural Plant Raw Material Extraction → Ethanol-Water Circulation Refining → Macroporous Resin Purification → Preparative HPLC Separation → Low-Temperature Recrystallization → Vacuum Drying |
| Solubility | Slightly soluble in cold water, soluble in hot ethanol, methanol and organic solvents; soluble in alkaline solutions; stable in acidic and neutral environments; insoluble in petroleum ether |
| Core Feature | High-purity natural flavonoid monomer, stable chemical structure, multi-target biological activity, powerful anti-inflammatory and neuroprotective properties, high experimental repeatability and formula stability |
| Package | 1g/5g/10g amber sealed bottle, 100g/1kg vacuum drum; moisture-proof & light-proof vacuum packaging, customized specifications supported |
| Storage | Store in vacuum-sealed, low-temperature, dry and dark conditions; avoid high temperature, strong light, humid air and alkaline environment to prevent flavonoid structural decomposition and activity loss |
| Shelf Life | 24 months under standard sealed low-temperature dark storage |
Product Description
Luteolin is a premium high-purity natural flavonoid monomer, chemically defined as 3′,4′,5,7-Tetrahydroxyflavone, widely extracted from natural medicinal and edible plants such as honeysuckle, chrysanthemum and perilla. As one of the most researched active flavone compounds, Luteolin integrates powerful antioxidant, multi-target anti-inflammatory, neuroprotective, immunomodulatory and anti-tumor auxiliary activities, occupying an important position in biomedical research, skincare development and functional health product manufacturing. We provide two mainstream high-grade specifications: 98% research grade and 99% premium functional grade, produced through full-process low-temperature purification and preparative HPLC refining technology.
Different from ordinary plant crude extracts containing mixed flavonoids, cellulose and pigment impurities, our refined Luteolin is a single pure monomer with fixed molecular structure and accurate content. The standardized production process completely removes residual solvents, heavy metals and heterologous impurities, effectively eliminating experimental interference and finished product formula instability. All production procedures comply with GMP dust-free purification standards, ensuring ultra-high purity, stable biological activity and excellent batch-to-batch consistency for every batch of products.
In antioxidant performance, Luteolin efficiently scavenges intracellular reactive oxygen species, inhibits lipid peroxidation chain reactions, reduces cellular oxidative damage, and delays body and skin aging caused by long-term oxidative stress. Its free radical scavenging capacity is superior to many conventional plant flavonoids, effectively improving sub-health problems such as physical fatigue and metabolic decline.
In anti-inflammatory regulation, Luteolin blocks multiple inflammatory signaling pathways, significantly reduces the secretion of pro-inflammatory cytokines, relieves acute and chronic low-grade inflammation, and alleviates tissue inflammatory damage. It also exerts unique neuroprotective effects, protecting nerve cells from oxidative and inflammatory damage, helping maintain central nervous system stability, and providing effective raw material support for neurodegenerative disease-related pharmacological research.
In immune regulation, Luteolin modulates immune cell proliferation and cytokine balance, enhances innate immune defense capabilities, and maintains long-term immune homeostasis. In skincare applications, its excellent antioxidant and anti-inflammatory properties resist UV photoaging, relieve skin redness and sensitivity, repair damaged skin barriers, fade dullness and fine lines, and improve overall skin texture, making it a core raw material for high-end anti-aging and soothing skincare formulas.
Our high-purity Luteolin presents uniform light yellow crystalline fine powder with delicate texture, no agglomeration and no peculiar smell. Every batch undergoes full-index quality inspection including HPLC purity calibration, NMR structural identification, mass spectrometry molecular verification and cell-level activity testing. Strict quality control ensures compliance with USP, EP, cosmetic-grade and food-grade international raw material standards. With stable physical and chemical properties and wide formula compatibility, it is widely applicable for scientific research experiments, health supplement production and cosmetic formula development.
Functions & Benefits
Powerful Natural Antioxidant & Anti-Aging
Efficiently removes excess free radicals in the body, inhibits lipid peroxidation and cellular oxidative damage, delays skin and tissue aging, and improves sub-health state caused by long-term oxidative stress.
Multi-Target Anti-Inflammatory Relief
Inhibits multiple inflammatory signaling pathways, reduces pro-inflammatory factor release, relieves chronic low-grade inflammation and acute inflammatory irritation, and reduces tissue inflammatory damage.
Excellent Neuroprotective Effect
Protects nerve cell activity, resists nerve damage caused by oxidation and inflammation, stabilizes central nervous system function, and supports neuropharmacology and cognitive health research.
Immune Balance & Defense Enhancement
Regulates immune cell activity and cytokine secretion balance, enhances body innate immune defense, corrects immune imbalance, and maintains systemic immune homeostasis.
Skin Repair & Anti-Photoaging
Resists UV-induced skin oxidative damage and photoaging, relieves sensitive redness and inflammation, repairs skin barrier damage, fades dullness and fine lines, and brightens skin tone.
High-Purity Monomer & Zero Formula Interference
98%–99% ultra-high purity single flavonoid monomer, free of miscellaneous plant impurities and solvent residues, stable molecular structure, ensuring accurate experimental data and consistent finished product efficacy.
High Safety & Wide Compatibility
Derived from natural edible plant sources, low irritation and high biological safety, compatible with oral health products and external skincare formulas, suitable for long-term mild conditioning and formula development.
Applications
Biomedical & Pharmacological Research
Used as standard flavonoid monomer reagent for antioxidant, anti-inflammatory, neuroprotective, immune regulation and anti-tumor auxiliary mechanism research in university and institutional laboratories.
Immune & Anti-Inflammatory Health Supplements
Core functional raw material for immune balancing, anti-inflammatory conditioning and antioxidant anti-aging health products, supporting daily body sub-health improvement.
High-End Anti-Aging Skincare Products
Applied in anti-photoaging essence, soothing repair lotion, anti-sensitive cream and antioxidant skincare products to improve skin aging and sensitive problems.
Neuroprotection & Cognitive Health R&D
Special raw material for nerve protection and cognitive health functional product development, serving neurodegenerative disease auxiliary research and health formula innovation.
Functional Food & Nutritional Additives
Used as natural antioxidant and nutritional additive in functional foods and nutritional products to enhance product health value and oxidation resistance.
Natural Plant Pharmacology Teaching Experiment
Served as standardized high-purity Luteolin reagent for natural flavonoid structure identification and pharmacological teaching experiments to ensure stable and repeatable experimental results.
FAQ
Q1: What is Luteolin used for?
A: Luteolin is a high-activity natural flavonoid monomer, mainly used for antioxidant anti-aging, multi-target anti-inflammation, neuroprotection and immune regulation. It is widely applied in pharmacological research, high-end skincare development and immune health supplement production.
Q2: What makes Luteolin different from other flavonoids?
A: Luteolin has unique neuroprotective activity in addition to conventional antioxidant and anti-inflammatory effects. It features mild action, high safety and multi-target efficacy, compatible with both medical research, oral health products and external skincare formulas.
Q3: What are your product advantages?
A: Our Luteolin adopts preparative HPLC fine purification and low-temperature recrystallization technology, reaching 98%/99% ultra-high purity with zero impurity residues, stable monomer structure, consistent batch activity and reliable experimental repeatability.
Q4: How to store Luteolin correctly?
A: Luteolin flavonoid structure is sensitive to high temperature, strong light, humidity and alkaline environments. It must be vacuum-sealed and stored in low-temperature, dry and dark conditions to avoid active ingredient decomposition and ensure 24-month shelf life.
Q5: What does qualified high-purity Luteolin look like?
A: Premium Luteolin is uniform light yellow crystalline fine powder with delicate crystal texture, odorless, no caking, no discoloration and no visible foreign impurities.
Q6: Can I get free test samples?
A: Yes, we provide free Luteolin test samples for academic research, pharmacological efficacy testing and formula trial production. Bulk orders support customized purity and personalized packaging solutions.
