Product Introduction
| Item | Specification |
| Product Name | Icariin |
| Synonyms | Epimedium Extract; Horny Goat Weed Extract; Icariin Flavonoid Monomer |
| CAS Number | 489-32-7 |
| Molecular Formula | C₃₃H₄₀O₁₅ |
| Molecular Weight | 676.66 g/mol |
| Appearance | Light yellow crystalline fine powder, faint unique herbal fragrance, uniform texture, no caking, no impurities or discoloration under sealed dry and dark storage |
| Purity (HPLC) | Icariin ≥98.0% / ≥99.0% (Research Grade / Premium Functional Grade, customizable) |
| Loss on Drying | ≤ 0.2% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / NMR / Mass Spectrometry / IR Spectrum / Biological Activity Assay |
| Production Method | Epimedium Herb Raw Material Ethanol-Water Dual Extraction + Macroporous Resin Gradient Purification + Preparative HPLC Refining + Low-Temperature Vacuum Recrystallization |
| Solubility | Soluble in methanol, ethanol, DMSO and hot water; slightly soluble in cold water; insoluble in petroleum ether and aliphatic solvents; avoid strong alkaline environment and long-term high temperature heating |
| Core Feature | High-purity single flavonoid monomer from natural Epimedium, stable chemical structure, outstanding bone-protective and antioxidant activity, high bioavailability and reliable experimental repeatability |
| Package | 1g/5g/10g amber sealed bottle, 100g/1kg vacuum drum; moisture-proof & light-proof vacuum packaging, customized specifications supported |
| Storage | Store in vacuum-sealed, low-temperature, dry and dark conditions; avoid high temperature, strong light and humid air to prevent flavonoid decomposition and activity attenuation |
| Shelf Life | 24 months under standard sealed low-temperature dark storage |
Product Description
Icariin is a high-purity natural flavonoid glycoside monomer isolated and refined from the dried aerial parts of Epimedium brevicornum Maxim, commonly known as Horny Goat Weed, a classic precious medicinal herb. As the core active marker ingredient of Epimedium extract, Icariin undertakes the main pharmacological activities of Epimedium, including bone metabolism regulation, antioxidant protection, anti-fatigue and cardiovascular conditioning. We provide two premium grades: Research Grade 98% Icariin and Premium Functional Grade 99% Icariin, produced through standardized high-quality epimedium raw material screening, low-temperature ethanol-water dual-phase extraction, multi-stage macroporous resin impurity removal and decolorization, preparative HPLC precise purification and vacuum recrystallization technology.
Different from ordinary crude epimedium total extract which contains a variety of mixed flavonoids, plant fibers, chlorophyll and unstable active components, our refined Icariin is a single purified monomer with fixed molecular structure and accurate content. The fully enclosed light-shielded and low-temperature production process completely removes heterologous impurities, heavy metals and residual solvents, eliminating experimental interference and formula instability problems caused by impure ingredients. Every batch of products maintains ultra-high purity and stable component ratio, ensuring highly repeatable pharmacological experimental data and consistent efficacy of finished health and skincare products.
In bone health regulation, Icariin has a unique dual regulatory mechanism on osteoblasts and osteoclasts. It can effectively promote osteoblast proliferation and bone matrix synthesis, inhibit excessive osteoclast activity and bone resorption, improve bone density and bone microstructure, and is widely used in auxiliary conditioning of bone loss and sub-health bone problems. In terms of antioxidant and anti-aging, Icariin efficiently scavenges intracellular reactive oxygen free radicals, blocks lipid peroxidation reactions, reduces oxidative damage to cells and tissues, delays body aging, and improves physical sub-health caused by long-term fatigue and stress.
For cardiovascular protection, high-purity Icariin protects vascular endothelial cell activity, improves systemic microcirculation, assists in regulating blood lipid metabolism, maintains vascular elasticity and cardiovascular system stability. In addition, Icariin has mild anti-inflammatory and endocrine-regulating properties, which can relieve chronic low-grade inflammation in the body, improve physical vitality and fatigue state, and provide safe and gentle natural conditioning effects. In skincare applications, its excellent antioxidant activity can resist external environmental damage and photoaging, improve skin dullness and aging problems, and is suitable for high-end anti-aging repair formula development.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our Icariin adopts full-process low-temperature closed production to avoid structural damage and activity degradation of flavonoid active ingredients caused by high temperature and strong light. The finished product is uniform light yellow crystalline fine powder with delicate texture, no agglomeration, no peculiar smell and pure herbal fragrance, fully compliant with USP, EP, food-grade and cosmetic-grade international raw material standards.
Functions & Benefits
Professional Bone Protection & Bone Metabolism Regulation
Icariin dual-regulates osteoblast and osteoclast balance, promotes bone tissue synthesis, inhibits abnormal bone resorption, effectively improves bone density, repairs bone microstructure damage, and assists in preventing and conditioning bone loss problems.
Powerful Antioxidant & Anti-Aging Effect
Scavenges excess free radicals in the body, inhibits lipid peroxidation and cellular oxidative damage, delays tissue and organ aging accumulation, relieves fatigue sub-health, and improves overall body vitality.
Cardiovascular Protection & Microcirculation Improvement
Protects vascular endothelial integrity, enhances microcirculation metabolism, assists in balancing blood lipid levels, maintains vascular elasticity, and stabilizes cardiovascular system health.
Significant Anti-Fatigue & Vitality Enhancement
Optimizes human energy metabolism pathways, accelerates fatigue metabolite decomposition, relieves physical exhaustion caused by long-term work, staying up late and high pressure, and improves physical endurance.
Skin Anti-Oxidation & Anti-Photoaging
Resists UV and environmental oxidative damage to the skin, reduces free radical erosion, improves skin dullness and fine lines, delays light aging, and presents excellent skincare repair effects.
High Purity Monomer & Zero Formula Interference
98%–99% high-purity single flavonoid monomer, no miscellaneous plant impurities and solvent residues, stable chemical properties, ensuring accurate experimental data and consistent finished product efficacy.
Mild Natural & High Safety
Derived from pure natural epimedium herb, non-toxic and low-irritation, high biological safety, suitable for long-term oral conditioning and external skincare application with wide compatibility.
Applications
Bone Metabolism & Pharmacological Research
Used as a standard flavonoid monomer reagent for bone metabolism mechanism research, osteoporosis intervention experiments and skeletal tissue protection related pharmacological studies in laboratories.
Cardiovascular & Antioxidant Scientific Research
Core experimental material for vascular endothelial protection, blood lipid regulation and oxidative stress intervention research, supporting natural active ingredient pharmacological development.
Bone Health & Physical Conditioning Supplements
Key functional raw material for bone nourishing, bone density improvement and anti-fatigue health capsules, tablets and oral liquids, suitable for middle-aged and elderly sub-health conditioning products.
Anti-Aging & Repairing Cosmetic Raw Materials
Applied in high-end antioxidant essence, anti-photoaging lotion and skin repairing cream to improve skin aging and dullness, serving as natural plant anti-aging additive.
Functional Food & Daily Nourishing Products
Added into functional nourishing foods and solid drinks to improve human vitality, relieve physical fatigue and realize daily body sub-health conditioning.
University Lab Pharmacology Teaching Demonstration
Supplied as standard high-purity Icariin monomer reagent for natural flavonoid pharmacology, bone protection and antioxidant teaching experiments to ensure stable and accurate experimental results.
FAQ
Q1: What is Icariin used for?
A: Icariin is the core active flavonoid monomer of Epimedium, mainly used for bone health conditioning, antioxidant anti-aging, anti-fatigue and cardiovascular protection pharmacological research, as well as raw materials for functional health products and anti-aging cosmetics.
Q2: What is the difference between Icariin monomer and ordinary Epimedium extract?
A: Ordinary epimedium extract is a mixture of multiple flavonoids and plant impurities with unstable content; our Icariin is a purified single monomer with fixed purity and stable structure, featuring higher safety, better repeatability and more accurate efficacy for research and formula production.
Q3: What are your product advantages?
A: Our Icariin adopts preparative HPLC fine purification technology to reach 98%/99% high purity, with zero impurity residues, stable biological activity and excellent batch consistency, fully meeting scientific research and high-end product production standards.
Q4: How to store Icariin correctly?
A: Icariin flavonoid ingredients are sensitive to high temperature, strong light and humid environment, which will cause active ingredient decomposition and activity loss. It must be vacuum-sealed and stored in low-temperature, dry and dark conditions to guarantee 24-month shelf life.
Q5: What is the appearance of high-purity Icariin?
A: Qualified high-purity Icariin is uniform light yellow crystalline fine powder, with pure herbal fragrance, loose texture, no caking, no discoloration and no visible impurities.
Q6: Can I get free samples?
A: Yes, we provide free Icariin test samples for academic research, pharmacological efficacy testing and product formula trial production. Bulk orders support customized purity and personalized packaging solutions.
