Dioscin CAS 19057-60-4 Spirostanol Saponin from Dioscorea zingiberensis
Product Identification
| Item | Detail |
|---|---|
| Synonyms | Dioscin; 3-[(2-O-α-L-Rhamnopyranosyl-α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]-5α-spirostan-3β-ol; Parillin (related, from Smilax— different plant, same spirostanol saponin class, sometimes confused) |
| CAS RN | 19057-60-4 |
| Aglycone CAS (downstream) | Diosgenin 512-04-9 (acid hydrolysis product) |
| Molecular Formula | C₄₅H₇₂O₁₆ |
| MW | 869.05 |
| Botanical (main) | Dioscorea zingiberensisC.H. Wright (shield-leaf yam, “黄姜”, Shaanxi/Hubei/Sichuan) |
| Botanical (secondary) | D. nipponica(穿龙薯蓣), D. opposita(山药, low) |
| HS Code (ref) | 1302 / 2938 |
| Sibling (same plant family) | Diosgenin 512-04-9 (steroid API precursor, separate SKU) |
Description
Dioscin is the flagship spirostanol saponin of Dioscorea zingiberensis— the plant behind China’s “huang-jiang belt” (Shaanxi south / Hubei west / Sichuan north), and the botanical gateway to the entire corticosteroid / sex-hormone / spirolactone industrial chain (via Diosgenin).
Applications
B2B Bulk P.E. (tonnage) – D. zingiberensisalkali-EtOH extract, Dioscin 10% / 30% / 50% / 80% HPLC; Shaanxi/Hubei “huang-jiang” origin; TCM “wind-damp/invigorate” bulk; veterinary botanical; B2B PO confirm % + origin + alkali-process
Steroid API Precursor Chain – Dioscin P.E. → acid hydrolysis → Diosgenin 512-04-9 → double-bond → pregnenolone → corticosteroid/sex-hormone/spirolactone/OC pill; “diosgenin precursor / steroid intermediate botanical” B2B long-tail; if Diosgenin in SKU list cross-link “steroid duo”
TCM R&D / Antitumor Apoptosis – Dioscin ≥98% for HepG2/K562/MCF-7/A549, Bcl-2/Bax caspase, PI3K/Akt, NF-κB; inner-link “TCM saponin R&D” cluster (Ginsenoside Rg3 if in SKU) — spirostanol vs dammarane, search-intent separated
Lipid / Atherosclerosis (minor soft) – Dioscin “invigorate blood” TCM lit LDL/ox-LDL/SREBP-2; “TCM botanical lipid” soft, neighbor Guggulsterone (Ayurvedic) if in SKU
Reference Standard (≥98%) – for D. zingiberensisP.E. QC (Dioscin%), Diosgenin conversion yield check, antitumor R&D
