Product Introduction
| Item | Specification |
| Product Name | Corilagin |
| Synonyms | ; Ellagitannin; Corilagin tannin |
| CAS Number | 23094-69-1 |
| Molecular Formula | C₂₇H₂₂O₁₈ |
| Molecular Weight | 634.46 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 200–203°C |
| Density | 2.1±0.1 g/cm³ |
| Solubility | Soluble in DMSO, methanol, ethanol and polar organic solvents, slightly soluble in water |
| Natural Source | Naturally extracted from Phyllanthus emblica, Geranium wilfordii and leafy medicinal plants, a high-value hydrolyzable ellagitannin monomer |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry inert gas conditions; avoid high temperature, strong light and oxidation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Corilagin powder is a high-purity natural ellagitannin active ingredient, available in 98% and 99% HPLC grades. Corilagin (CAS 23094-69-1), known as , is a premium hydrolyzable tannin compound widely distributed in Phyllanthus emblica, geranium leaves and various medicinal plants. As a core bioactive polyphenol monomer, it features a compact multi-hydroxyl molecular structure, delivering outstanding comprehensive biological activity including high-efficiency antioxidant, targeted anti-inflammation, unique anti-fibrosis, broad-spectrum antiviral and lipid-regulating properties. It integrates multi-dimensional core benefits such as free radical scavenging, inflammatory inhibition, skin fibrosis improvement, cholesterol synthesis suppression and microbial resistance. Widely applied in sensitive soothing skincare, anti-fibrotic anti-aging products, lipid metabolism health supplements and advanced biomedical pharmacological research. As a professional bulk Corilagin supplier, we provide high-purity, low-impurity, stable-batch natural ellagitannin raw materials for global industrial and scientific research clients.
Corilagin belongs to the high-activity ellagitannin subclass of natural polyphenols, with distinct functional advantages different from Geraniin, lignans and flavonoid ingredients. It possesses exclusive anti-fibrosis and squalene epoxidase inhibitory effects, making it uniquely effective in improving skin aging fibrosis and regulating cholesterol synthesis. Its abundant phenolic hydroxyl groups rapidly scavenge intracellular ROS free radicals, block oxidative stress cascades and reduce skin photoaging damage. Different from ordinary antioxidants, Corilagin specifically targets the TGF-β1 signaling pathway, effectively inhibiting skin fibroblast hyperplasia and extracellular matrix deposition, improving skin sagging, stiffness and aging texture caused by fibrosis. In metabolic regulation, it inhibits squalene epoxidase activity to reduce cholesterol production, assisting in blood lipid balance and cardiovascular health maintenance. It also exerts strong broad-spectrum antiviral, antibacterial and anti-tumor activity, with mild properties and excellent biocompatibility for long-term topical and oral application.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Corilagin powder adopts low-temperature solvent directional extraction and multi-stage high-precision column chromatography purification technology. We select high-quality emblica and geranium raw materials with stable tannin content, completely remove plant fibers, macromolecular proteins, residual sugars and invalid polymer impurities through gradient elution purification, and fully retain the complete molecular structure and biological activity of Corilagin. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The refined purification process solves the problems of impure traditional plant tannin extracts and unstable activity, ensures uniform white crystalline powder appearance and consistent batch efficacy, meeting the strict formula development and high-precision experimental requirements of global customers.
Every batch of Corilagin powder undergoes strict multi-dimensional quality inspection, including HPLC high-precision purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished powder features low impurity content, good solubility in polar solvents, strong structural stability and outstanding batch consistency. All products comply with international cosmetic additive regulations, natural functional food safety standards and high-end research-grade compound specifications, supporting safe and standardized application in anti-fibrotic skincare, lipid regulation health products, antiviral functional foods and cutting-edge biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Corilagin supply. Whether you need anti-fibrotic anti-aging and soothing active raw materials for high-end skincare formulas, natural lipid-lowering and metabolic conditioning ingredients for health products, or high-purity ellagitannin compounds for antiviral, anti-fibrosis and anti-tumor pharmacological research, our Corilagin powder is a cost-effective and high-value bulk raw material choice for global buyers.
Functions & Benefits
Powerful Antioxidant & Anti-Photoaging (Core Benefit)
Corilagin efficiently scavenges DPPH, ABTS and intracellular ROS free radicals, inhibits lipid peroxidation and UV-induced oxidative damage. It reduces skin oxidative stress, delays photoaging and dullness, and builds a stable endogenous antioxidant defense barrier, providing long-term anti-aging protection for skin cells.
Exclusive Anti-Fibrosis & Skin Texture Repair
As a natural TGF-β1 pathway inhibitor, Corilagin effectively blocks skin fibroblast proliferation and extracellular matrix accumulation. It improves skin fibrosis stiffness, sagging and rough texture caused by aging and inflammation, repairs damaged skin tissue, and restores smooth and tender skin condition, offering unique anti-fibrotic anti-aging effects that ordinary antioxidants lack.
Broad-Spectrum Anti-Inflammatory & Sensitive Skin Soothing
Corilagin suppresses NF-κB and MAPK inflammatory signaling cascades, reduces the release of TNF-α, IL-6 and multiple pro-inflammatory factors. It relieves acute UV redness, chronic low-grade inflammation and sensitive skin irritation, stabilizes skin microecology, and repairs fragile skin barriers efficiently and mildly.
Squalene Epoxidase Inhibition & Lipid Regulation
Corilagin specifically inhibits squalene epoxidase, the key rate-limiting enzyme of cholesterol synthesis, significantly reducing endogenous cholesterol production. It optimizes blood lipid metabolism, lowers lipid deposition, assists in improving hyperlipidemia, and protects cardiovascular metabolic health.
Broad-Spectrum Antiviral & Antibacterial Activity
Modern pharmacological studies verify that Corilagin has excellent inhibitory effects on multiple viruses and harmful bacteria including Staphylococcus aureus. It inhibits retrovirus reverse transcriptase activity, reduces microbial infection-induced inflammatory damage, and enhances systemic immune defense capability for daily health protection.
Multi-Target Anti-Tumor & Hepatoprotective Effect
Corilagin inhibits the proliferation, migration and invasion of various malignant tumor cells, induces tumor cell apoptosis, and exerts broad-spectrum chemoprevention effects. Meanwhile, it relieves hepatic inflammatory damage and toxic injury, protecting liver function and improving body metabolic detoxification capacity.
Applications
Anti-Fibrotic Anti-Aging & Sensitive Repair Skincare
Corilagin is widely used in high-end anti-aging essences, skin texture repair creams, post-sun soothing products and sensitive skin conditioning formulas. It integrates antioxidant anti-aging, anti-fibrotic texture refinement and anti-inflammatory soothing multi-effects, effectively improving skin sagging, roughness, fibrosis aging and sensitive redness, being a rare multi-functional tannin active ingredient for targeted skin aging repair.
Lipid Balance & Metabolic Health Supplements
Applied in cholesterol-lowering health products, cardiovascular protection formulas and daily metabolic conditioning supplements. It inhibits endogenous cholesterol synthesis, optimizes blood lipid levels, reduces lipid deposition, and provides safe natural metabolic and cardiovascular health care for sub-health groups.
Antiviral & Antioxidant Functional Food
Used in high-antioxidant functional foods, immune-enhancing dietary supplements and daily health foods. It improves product antioxidant and antibacterial activity, inhibits microbial growth, extends product shelf life, and upgrades comprehensive nutritional health value.
Biomedical & Pharmacological Research
Widely used in ellagitannin structure-activity research, anti-fibrosis pharmacology, lipid synthesis inhibition mechanism, antiviral and anti-tumor research, serving as a core standard natural tannin research compound for university laboratories and medical research institutions.
High-End Tannin Ingredient Innovation
As a unique anti-fibrotic ellagitannin monomer, it fills the market gap of targeted skin fibrosis repair raw materials, supports innovative R&D of high-end anti-aging skincare and lipid metabolic health products, and promotes the iterative upgrade of natural polyphenol functional ingredients.
FAQ
Q1: What is Corilagin powder used for?
A: Corilagin powder is a high-purity natural ellagitannin compound extracted from medicinal plants. It is mainly used for anti-fibrotic skin repair, antioxidant anti-aging and sensitive soothing skincare, natural lipid-lowering metabolic conditioning, as well as biomedical antiviral, anti-tumor and hepatoprotective pharmacological research.
Q2: What are the unique advantages of Corilagin?
A: Different from ordinary polyphenols and tannins, Corilagin has exclusive natural anti-fibrosis and cholesterol synthesis inhibitory activity. It targets skin fibrosis aging that common antioxidants cannot improve, while achieving dual effects of skin anti-aging and body lipid metabolism regulation, with irreplaceable targeted application value.
Q3: Is Corilagin safe for cosmetic and food use?
A: Yes, Corilagin is a pure natural plant-derived active ingredient extracted from edible medicinal plants. It features mild properties, low irritation and high biocompatibility, complying with international cosmetic and food-grade additive safety standards, supporting long-term topical skincare and oral health product application.
Q4: What is the difference between Corilagin and Geraniin?
A: Geraniin focuses on anti-glycation, whitening and hypoglycemic effects, while Corilagin specializes in anti-fibrosis skin repair and cholesterol reduction. Corilagin is the optimal ingredient for improving skin texture fibrosis and regulating lipid synthesis, forming a complementary functional system with other ellagitannin ingredients.
Q5: How to store Corilagin powder correctly?
A: Corilagin powder is sensitive to high temperature, strong light and oxidation. It needs to be tightly sealed, protected from light, filled with inert gas and stored at 2-8°C in a dry environment. Standard low-temperature sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Corilagin samples?
A: Yes, we provide free Corilagin powder samples for anti-fibrotic skincare formula debugging, metabolic health product development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
