Linarin CAS 480-36-4 Acacetin-7-O-β-D-Rutinoside Flavone O-Glycoside from Buddleja officinalis Chrysanthemum indicum

Product Identification
| Item | Detail |
|---|---|
| Synonyms | Linarin; Buddlejoside; Acaciin; Acacetin-7-O-β-D-rutinoside; 5-Hydroxy-2-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one |
| CAS RN | 480-36-4 |
| Aglycone (pair) | Acacetin CAS 480-44-4 (5,7-diOH-4′-OMe flavone, C₁₆H₁₂O₅, 284) — O-glycoside pair #6 |
| Sibling (same-sugar diff-aglycone) | Luteoloside CAS 5373-11-5 (luteolin-7-O-rutinoside, 3′,4′-diOH B-ring) — diff PO |
| Molecular Formula | C₂₈H₃₂O₁₄ |
| MW | 592.55 |
| Plant A (ChP) | Buddleja officinalisMaxim. (Loganiaceae) — flower bud, “密蒙花 Mi-Meng-Hua”, ChP Linarin ≥0.50% |
| Plant B (ChP) | Chrysanthemum indicumL. (Asteraceae) — capitulum, “野菊花 Ye-Ju-Hua”, ChP Linarin reported (~≥0.80% lit, verify) + chlorogenic% |
| ChP 2020 (Buddleja) | “清热养肝, 明目退翳” — liver-eye TCM |
| HS Code (ref) | 1302 / 2938 |
Description
Linarin is a natural chemical compound widely found in medicinal plants such as wild chrysanthemum, Buddleja officinalis, mint, and Bupleurum. It exists as a white crystalline powder that is readily soluble in methanol. Linarin is primarily derived from wild chrysanthemum, with relatively high concentrations found in the Dabie Mountains region at the junction of Anhui, Henan, and Hubei provinces.
Applications

Pharmaceutical Research Intermediates Anti-inflammatory, antipyretic, neuroprotective, liver-protective, hypoglycemic, cardiovascular protective raw material; research for rhinitis, pharyngitis, sleep support, osteoporosis drugs.
Dietary Supplements & Functional Food Throat-clearing capsules, stress & sleep support oral powder, liver-care herbal drinks, anti-oxidation nutritional tablets.
Cosmetic Active Ingredient Sensitive skin soothing, anti-acne, anti-inflammatory, anti-photoaging serum, mask, facial cream and body care products.
Lab HPLC Reference Standard Quantitative testing marker for chrysanthemum herbal extracts; reagent for cell pharmacology experiments.




