Betaine CAS: 107-43-7

Betaine CAS: 107-43-7
1.Dietary Supplements & Sports Nutrition
2.Cosmetics & Personal Care
3.Food & Functional Beverages

Betaine Anhydrous Bulk Powder Manufacturer & Supplier GMP Certified

Betaine

Product Introduction

Betaine anhydrous (CAS 107-43-7), also known as trimethylglycine (TMG), is a naturally occurring amino acid derivative found abundantly in sugar beets (Beta vulgaris), spinach, quinoa, wheat germ, shellfish, and other foods. As a zwitterionic compound bearing three methyl groups on its nitrogen atom, betaine is one of nature’s most potent methyl donors — a biochemical function central to dozens of critical physiological processes including one-carbon metabolism, homocysteine regulation, liver protection, osmoprotection, and cellular methylation.

Product Specifications

ParameterFood/Nutraceutical GradeCosmetic GradeFeed Grade
Assay (Betaine content)≥ 98.0% (HPLC)≥ 98.0% (HPLC)≥ 96.0%
AppearanceWhite crystalline powderWhite crystalline powderOff-white powder/granule
Loss on Drying≤ 0.5%≤ 0.5%≤ 1.0%
Residue on Ignition≤ 0.1%≤ 0.1%≤ 1.0%
pH (5% solution)5.5 – 7.55.5 – 7.55.0 – 8.0
Heavy Metals (Pb)≤ 10 ppm≤ 10 ppm≤ 20 ppm
Arsenic (As)≤ 2 ppm≤ 2 ppm≤ 5 ppm
Total Plate Count≤ 1,000 CFU/g≤ 100 CFU/g≤ 5,000 CFU/g
Yeast & Mold≤ 100 CFU/g≤ 10 CFU/g≤ 200 CFU/g
E. coliNegativeNegativeNegative
SalmonellaNegativeNegativeNegative
Particle Size≥80 mesh (95%)≥100 mesh (95%)≥40 mesh (90%)
CertificationsISO, KOSHER, HALAL, GMPISO, COSMOS/Ecocert eligibleISO, GMP Feed

Applications

Betaine

Dietary Supplements & Sports Nutrition (Dominant Segment):

Betaine anhydrous is among the top 10 most consumed sports nutrition ingredients globally, driven by strong clinical evidence for performance enhancement and body recomposition. Common supplement applications include:

  • Pre-workout powders: 1.25–2.5 g per serving alongside creatine, beta-alanine, caffeine
  • Post-workout recovery formulas: Combined with protein and BCAAs
  • Cardiovascular health capsules: 500 mg–2 g per serving with CoQ10, omega-3, B vitamins
  • Liver support supplements: 500 mg–3 g with milk thistle, NAC, phosphatidylcholine
  • Methylation support formulas: With methylfolate, methylcobalamin, SAMe
  • Weight management supplements: Combined with L-carnitine, CLA, green tea extract
  • Anti-aging formulas: With NMN, resveratrol, alpha-lipoic acid, vitamin E

Cosmetics & Personal Care:

Betaine is a premium cosmetic ingredient valued for its multi-functional properties in skincare and haircare formulations. INCI name: BETAINE.

  • Skincare moisturizers and serums: Humectant function attracts and retains moisture; improves skin hydration at 0.5–5.0% use level
  • Shampoos and conditioners: Reduces irritation of anionic surfactants; improves foam quality and feel; anti-static effect on hair; typical use 1–5%
  • Sensitive skin formulations: Skin-calming and redness-reducing properties; compatible with all major cosmetic ingredient classes
  • Anti-aging serums: Cell-protective osmolyte function; supports collagen synthesis via methylation pathways
  • Sunscreen formulations: Stabilizes UV filters; improves skin feel
  • Body lotions and creams: Texture improvement; moisture-binding capacity

Food & Functional Beverages:

  • Functional sports and energy beverages: Added at 500 mg–2.5 g per serving
  • Protein powders and meal replacement shakes: Methylation support function
  • Fortified breakfast cereals and baked goods: Enrichment for homocysteine management
  • Salt reduction systems: Betaine’s slight salty taste supports sodium reduction
  • Flavor enhancement: Contributes clean, slightly sweet-salty taste note to savory products