PQQ Pyrroloquinoline Quinone CAS :72909-34-1

Product Introduction

ItemSpecification
Product NamePQQ
SynonymsPyrroloquinoline Quinone; Methoxatin; PQQ Coenzyme Powder
CAS Number72909-34-1
Molecular FormulaC₁₄H₆N₂O₈
Molecular Weight334.21 g/mol
AppearanceOrange-red crystalline fine powder, odorless, uniform crystal texture, no caking, no impurities or discoloration under standard sealed storage conditions
Purity (HPLC)PQQ ≥99.0% (Premium Functional Grade, customizable)
Melting Point220–222°C (lit.)
Loss on Drying≤ 0.5%
Residue on Ignition≤ 0.1%
Testing MethodHPLC / NMR / Mass Spectrometry / IR Spectrum / Biological Activity Assay
Production MethodMicrobial Fermentation Technology → Fermentation Liquid Concentration → Macroporous Resin Purification → Preparative HPLC Refining → Low-Temperature Recrystallization → Vacuum Freeze Drying
SolubilitySoluble in water, methanol and ethanol; slightly soluble in organic solvents; stable in neutral and acidic environments; sensitive to strong alkaline and high-temperature long-term exposure
Core Feature99% high-purity bioactive coenzyme, powerful mitochondrial activation and regeneration capacity, superior antioxidant activity, stable molecular structure, high biological activity and batch consistency for health products and scientific research
Package1g/5g/10g amber sealed bottle, 100g/1kg vacuum drum; moisture-proof & light-proof vacuum packaging, customized specifications supported
StorageStore in vacuum-sealed, low-temperature, dry and dark conditions; avoid high temperature, strong light, humid air and strong alkaline environment to prevent molecular structure damage and activity attenuation
Shelf Life24 months under standard sealed low-temperature dark storage

Product Description

PQQ (Pyrroloquinoline Quinone), also known as Methoxatin, is a rare and high-activity natural bioactive coenzyme existing in microorganisms, plants and human tissues. As a vital redox cofactor, PQQ is famous for its unique mitochondrial biogenesis function, which is different from conventional antioxidants. Our PQQ powder adopts advanced microbial fermentation combined with preparative HPLC fine purification technology, reaching 99% ultra-high purity, with stable molecular structure, ultra-low impurity content and durable biological activity, fully meeting high-end health product production and biomedical research standards.

Different from common plant extracts and ordinary antioxidant ingredients, high-purity PQQ is a single active coenzyme monomer with precise chemical structure and targeted biological efficacy. The whole production process adopts sterile fermentation and low-temperature freeze-drying technology, which completely retains the active structure of PQQ, removes fermentation residues, heterologous proteins and harmful impurities, and solves the problems of unstable activity and low purity of traditional crude PQQ products. All production procedures comply with GMP dust-free purification standards, ensuring excellent batch-to-batch consistency and experimental repeatability.

PQQ possesses outstanding mitochondrial activation and regeneration capabilities. It can effectively stimulate the proliferation and repair of intracellular mitochondria, improve cellular energy metabolism efficiency, relieve chronic fatigue caused by insufficient energy supply, and enhance body vitality. As a super antioxidant, PQQ’s free radical scavenging ability is far superior to conventional antioxidants such as vitamin C and E. It can deeply remove intracellular reactive oxygen species, inhibit lipid peroxidation, reduce cellular oxidative damage, and delay whole-body and skin aging.

In neuroprotection and brain health regulation, PQQ protects nerve cells from oxidative and inflammatory damage, promotes nerve cell repair and growth, improves cerebral microcirculation, enhances memory and concentration, and effectively relieves brain fatigue and cognitive decline caused by aging and long-term high-intensity work. It also exerts significant anti-inflammatory and immune-balancing effects, inhibiting chronic low-grade inflammation in the body and maintaining systemic immune homeostasis.

In skincare and anti-aging fields, PQQ resists cellular photoaging and oxidative aging, repairs damaged skin energy circulation, improves dull skin, fine lines and sagging problems caused by energy decline, and revitalizes skin vitality. With mild properties and high safety, it is compatible with various oral health formulas and external skincare formulas, becoming a core raw material for high-end anti-aging and energy health products.

Our premium PQQ presents uniform orange-red crystalline fine powder with delicate texture, no caking and no peculiar smell. Every batch undergoes full-index quality inspection including HPLC purity calibration, NMR structural identification, mass spectrometry molecular verification and cell-level activity testing. Strict quality control complies with international food-grade and cosmetic-grade raw material standards. With stable physical and chemical properties and wide formula compatibility, it is widely used in brain health supplements, anti-aging products, energy metabolism formulas and biomedical pharmacological research.

We maintain long-term stable bulk inventory, support flexible supply from small trial samples to large-scale industrial orders, and provide customized packaging solutions to meet diversified R&D and mass production needs of global customers.

Functions & Benefits

Mitochondrial Regeneration & Energy Boost

Specifically activates mitochondrial biogenesis, repairs damaged mitochondria, improves cellular energy metabolism efficiency, relieves physical and mental fatigue, and enhances overall body vitality and endurance.

Super Antioxidant & Anti-Aging

Powerful free radical scavenging capacity eliminates intracellular oxidative stress damage, inhibits cellular aging and lipid peroxidation, delays body and skin aging, and improves sub-health state.

Professional Neuroprotection & Brain Health

Protects nerve cell activity, promotes nerve repair and regeneration, improves memory, concentration and mental clarity, and alleviates cognitive decline and brain fatigue effectively.

Chronic Anti-Inflammation & Immune Balance

Inhibits the release of pro-inflammatory factors, relieves chronic low-grade inflammation inside the body, regulates immune cell activity, and maintains long-term immune homeostasis.

Skin Energy Repair & Anti-Photoaging

Activates skin cell energy circulation, resists UV-induced photoaging and oxidative damage, repairs dull and sagging skin, fades fine lines, and restores skin elasticity and luster.

99% High-Purity Monomer & Stable Activity

Ultra-high purity single coenzyme monomer without fermentation residue and miscellaneous impurities, stable chemical structure, ensuring accurate experimental data and consistent finished product efficacy.

High Safety & Wide Formula Compatibility

Fermented from natural microbial strains, non-toxic and non-irritating, high biological safety, compatible with oral health supplements and high-end skincare formulas for long-term safe use.

Applications

Brain & Cognitive Health Supplements

Core functional raw material for brain nutrition, memory improvement and cognitive health products, widely used in daily brain care and anti-cognitive decline formulas.

Anti-Aging & Energy Health Products

Key ingredient for mitochondrial anti-aging, fatigue relief and physical vitality enhancement health supplements, improving long-term sub-health fatigue state.

High-End Anti-Aging Skincare Products

Applied in energy repair essence, anti-aging lotion, firming cream and antioxidant skincare products to improve skin aging, dullness and fine line problems.

Biomedical & Pharmacological Research

Used as standard PQQ coenzyme reagent for mitochondrial metabolism, neuroprotection, anti-aging and immune regulation mechanism research in scientific laboratories.

Functional Food & Nutritional Fortification

Served as natural nutritional fortifier and antioxidant in functional beverages and nutritional foods to enhance product anti-aging and energy-replenishing value.

Cell Metabolism Teaching Experiments

Standard high-purity PQQ experimental reagent for cell energy metabolism and coenzyme pharmacological teaching experiments, ensuring stable and repeatable experimental results.

FAQ

Q1: What is PQQ used for?

A: PQQ (Pyrroloquinoline Quinone) is a high-activity coenzyme ingredient, mainly famous for mitochondrial regeneration, super antioxidant, brain protection and energy metabolism improvement. It is widely used in anti-aging health supplements, cognitive care products, high-end skincare and biomedical research.

Q2: What makes PQQ different from ordinary antioxidants?

A: Unlike common antioxidants that only scavenge free radicals passively, PQQ can actively stimulate mitochondrial regeneration and repair cellular energy factories, fundamentally improve metabolic aging and fatigue problems, with longer-lasting and more comprehensive anti-aging efficacy.

Q3: What are your product advantages?

A: Our PQQ adopts sterile microbial fermentation + preparative HPLC refining technology, reaching 99% ultra-high purity, zero residual impurities, stable coenzyme activity, consistent batch efficacy and excellent experimental repeatability, meeting international high-end raw material standards.

Q4: How to store PQQ correctly?

A: PQQ active structure is sensitive to high temperature, strong light, humidity and alkaline environments. It must be vacuum-sealed and stored in low-temperature, dry and dark conditions to avoid activity loss and structural decomposition, ensuring 24-month valid shelf life.

Q5: What does qualified high-purity PQQ look like?

A: Premium 99% PQQ is uniform orange-red crystalline fine powder with delicate crystal texture, odorless, no caking, no discoloration and no visible foreign impurities.

Q6: Can I get free test samples?

A: Yes, we provide free PQQ test samples for academic research, pharmacological efficacy testing and formula trial production. Bulk orders support customized packaging solutions.