Hyaluronic Acid CAS :9004-61-9

Product Introduction

ItemSpecification
Product NameHyaluronic Acid
SynonymsSodium Hyaluronate; HA; Hyaluronan; Hyaluronic Acid Sodium Salt
CAS Number9004-61-9
Molecular Formula(C₁₄H₂₀NNaO₁₁)n
AppearanceWhite or off-white fine powder, odorless, tasteless, uniform texture, no caking or impurities under sealed dry storage
Purity (HPLC)≥99.0% (Cosmetic Grade / Food Grade / Pharmaceutical Grade, customizable)
Molecular WeightLow: 10kDa-100kDa; Medium: 100kDa-1000kDa; High: 1000kDa-3000kDa (customizable)
Loss on Drying≤ 10.0%
Residue on Ignition≤ 18.0%
Testing MethodHPLC / UV Spectrophotometry / Molecular Weight Detection / Microbiological Test
Production MethodMicrobial Fermentation / Biological Extraction / Ultrafiltration Purification / Low-Temperature Vacuum Drying & Sterilization
SolubilityFreely soluble in water, forming transparent viscous solution; insoluble in ethanol, acetone and organic solvents; stable in neutral and weak acidic environments
Core FeatureNatural high-molecular polysaccharide, super strong water-locking and moisturizing capacity, excellent biocompatibility, non-toxic and non-irritating, multi-molecular-weight customizable for diversified application scenarios
Package10g/100g sealed bottle, 1kg/25kg vacuum aluminum foil drum; moisture-proof & light-proof sealed packaging, customized specifications supported
StorageStore in vacuum-sealed, dry, dark and cool conditions; avoid high temperature, humid air and direct sunlight to prevent molecular degradation and agglomeration
Shelf Life24 months under standard sealed dry and dark storage

Product Description

Hyaluronic Acid (HA/Sodium Hyaluronate) is a natural linear polysaccharide compound widely existing in human skin, joints and connective tissues, known as the “King of Moisturizing” in the biological industry. Our high-purity Hyaluronic Acid is produced via advanced microbial fermentation technology, combined with multi-stage ultrafiltration purification, impurity removal and low-temperature vacuum drying process, with purity up to 99%. The product is divided into low, medium and high molecular weight grades, covering all mainstream application scenarios of cosmetics, food health products and pharmaceutical research, with pure composition, stable molecular activity and excellent batch consistency.

Different from ordinary low-purity hyaluronic acid products with impurity residues and unstable viscosity, our refined Hyaluronic Acid undergoes strict microbial purification and molecular screening. It completely removes fermentation residues, heterologous proteins and macromolecular impurities, ensuring high water solubility, transparent solution and no peculiar smell. Low molecular weight HA has strong skin penetration ability, which can quickly penetrate the basal layer of the skin, replenish deep moisture, repair damaged skin barriers and improve dry and rough skin texture. Medium molecular weight HA forms a dense moisturizing protective film on the skin surface to lock moisture for a long time and resist external dry stimulation. High molecular weight HA has excellent viscosity and lubricity, widely used in joint lubrication and medical adjuvant formulations.

In cosmetic application, Hyaluronic Acid delivers outstanding long-term moisturizing, anti-dry and skin smoothing effects. It effectively relieves skin dryness, peeling and fine lines caused by water loss, improves skin dullness and roughness, and maintains skin elasticity and tender state. With mild and non-irritating properties, it is compatible with almost all skincare ingredients, suitable for sensitive skin and long-term daily skincare use. In the field of health food, edible-grade hyaluronic acid assists in improving joint synovial fluid viscosity, lubricating joint cavities, reducing joint friction damage, and protecting joint health while improving body skin moisture from the inside out.

In pharmaceutical and scientific research fields, high-purity Hyaluronic Acid serves as a core biological raw material for tissue engineering research, wound repair experiments and medical adjuvant development. Its excellent biocompatibility, biodegradability and non-immunogenicity ensure safe and stable application in biological experiments and medical formulations. The whole production process complies with GMP purification standards, without any chemical additives, heavy metal residues and harmful impurities, fully meeting USP, EP, food-grade and cosmetic-grade international certification standards.

Manufactured by standardized dust-free purification workshop, our Hyaluronic Acid strictly controls fermentation temperature, purification precision and drying parameters to avoid molecular chain breakage and activity degradation. The finished product is uniform white fine powder with loose texture, no agglomeration and no peculiar smell. Every batch of products passes full-index quality inspection, including HPLC purity detection, molecular weight accurate calibration, viscosity test and microbial limit detection, ensuring stable product quality and reliable application effect.

We support long-term stable bulk supply, customized molecular weight and personalized packaging specifications. Whether for cosmetic formula development, health food production or laboratory scientific research, our high-purity Hyaluronic Acid can provide consistent and efficient raw material support for global manufacturers and research institutions.

Functions & Benefits

Superior Long-Lasting Moisturizing & Hydration

Hyaluronic Acid has ultra-high water-locking capacity, which can absorb water hundreds of times its own weight. It replenishes skin surface and deep moisture, forms a breathable moisturizing film, and effectively improves long-term dry and dehydrated skin problems.

Skin Barrier Repair & Anti-Dry Fine Lines

Low-molecular-weight HA penetrates deep into the skin to repair damaged keratin barriers, accelerate skin tissue metabolism, improve dry fine lines and dry peeling, and restore skin tenderness and smoothness.

Joint Lubrication & Physical Protection

Edible-grade hyaluronic acid optimizes synovial fluid viscosity, lubricates joint cavities, reduces bone friction and joint wear, relieves joint discomfort, and protects articular cartilage health.

Excellent Biocompatibility & Mild Safety

Derived from natural microbial fermentation, consistent with human endogenous components, non-toxic, non-irritating, non-allergic, with excellent biocompatibility, suitable for sensitive skin and long-term oral and external use.

High Purity & Stable Formula Compatibility

99% high purity without heterologous impurities and residual components, stable chemical properties, compatible with various skincare active ingredients and food raw materials, no formula conflict, ensuring stable finished product efficacy.

Anti-Oxidation & Skin Anti-Aging

Locking skin moisture to maintain cell vitality, slow down skin aging caused by water loss, improve skin dullness and sagging, and maintain skin elastic and youthful state.

Applications

High-End Moisturizing Skincare Products

Core functional raw material for facial essence, moisturizing lotion, cream, facial mask and toner, used for deep hydration, long-term moisturizing and dry line improvement skincare formulas.

Sensitive Skin Repair Cosmetics

Applied in mild repair skincare products for sensitive skin, relieving skin dryness sensitivity caused by barrier damage and improving skin tolerance.

Joint Health & Oral Beauty Supplements

Used in oral hyaluronic acid capsules, tablets and liquid drinks, realizing internal skin hydration and joint lubrication dual health care effects.

Biomedical & Wound Repair Research

Served as standard biological experimental material for tissue engineering, wound healing and cell culture research in medical and biological laboratories.

Daily Personal Care Products

Added into hand cream, body lotion, lipstick and other personal care products to improve product moisturizing effect and enhance skin-friendly comfort.

Pharmaceutical Excipient & Medical Adjuvant

Used as thickener, lubricant and sustained-release excipient in pharmaceutical preparations, widely applied in medical ointments and biological preparations.

FAQ

Q1: What is Hyaluronic Acid used for?

A: Hyaluronic Acid is a multi-functional natural biological raw material, mainly used for skincare moisturizing and barrier repair, joint health conditioning, as well as biomedical research and pharmaceutical excipient production.

Q2: What is the difference between different molecular weight HA?

A: Low molecular weight HA penetrates deep into the skin for internal repair; medium molecular weight HA locks surface moisture; high molecular weight HA provides strong viscosity and lubrication for joint and medical applications.

Q3: What are your product advantages?

A: Our Hyaluronic Acid reaches 99% high purity via advanced fermentation and ultrafiltration purification, with complete molecular activity, zero harmful residues, customizable molecular weight grades and excellent batch-to-batch consistency.

Q4: How to store Hyaluronic Acid correctly?

A: Hyaluronic Acid powder is sensitive to high temperature and humidity, which easily causes agglomeration and molecular degradation. It needs to be vacuum-sealed and stored in dry, cool and dark environment to ensure 24-month valid period.

Q5: What is the appearance of high-purity Hyaluronic Acid?

A: Qualified high-purity Hyaluronic Acid is uniform white fine powder, odorless and tasteless, loose texture without agglomeration, and can form transparent viscous liquid after dissolving in water.

Q6: Can I get free samples?

A: Yes, we provide free Hyaluronic Acid samples of different molecular weights for formula testing, efficacy verification and academic research. Bulk orders support customized specifications and professional packaging.