Product Introduction
| Item | Specification |
| Product Name | Epimedium Extract / Icariin |
| Synonyms | Icariin; Horny Goat Weed Extract; Epimedium Brevicornum Extract; 3-(2-Hydroxyphenyl)-8-(3-methylbut-2-enyl)-5,7-dihydroxy-4-oxo-4H-chromen-2-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside |
| CAS Number | 489-32-7 |
| Molecular Formula | C₃₃H₄₀O₁₅ |
| Molecular Weight | 676.66 g/mol |
| Appearance | Light yellow to brownish-yellow fine crystalline powder, slight characteristic herbal aroma, stable texture, no caking under sealed dry and dark storage conditions |
| Purity (HPLC) | ≥98.0% / ≥99.0% (Research Grade / Premium Functional Grade, customizable) |
| Loss on Drying | ≤ 0.2% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / NMR / Mass Spectrometry / IR Spectrum / Biological Activity Assay |
| Production Method | Epimedium Herb Raw Material Extraction + Alcohol Reflux Separation + Macroporous Resin Purification + Preparative HPLC Precision Refining + Low-Temperature Recrystallization |
| Melting Point | 228–230°C (lit.) |
| Boiling Point | 972.2°C at 760 mmHg (Predicted) |
| Density | 1.56 g/cm³ at 25°C |
| Flash Point | 307.2°C |
| Solubility | Slightly soluble in water, freely soluble in methanol, ethanol, DMSO and acetone; insoluble in petroleum ether; stable in dry dark environment, sensitive to high temperature and strong ultraviolet irradiation |
| Core Feature | Signature flavonoid glycoside active monomer of Epimedium brevicornum, classic natural plant-derived vitality-regulating ingredient, famous for bone-protective, immune-enhancing and anti-aging pharmacological activities |
| Package | 1g/5g/10g amber sealed bottle, 100g/1kg vacuum drum; moisture-proof & light-proof vacuum packaging, customized specifications supported |
| Storage | Store in vacuum-sealed, low-temperature, dry and dark conditions; avoid high temperature, strong light and humid air to prevent molecular oxidation and activity attenuation |
| Shelf Life | 24 months under standard sealed low-temperature dark storage |
Product Description
Epimedium Extract (High-Purity Icariin, CAS 489-32-7) is the core bioactive flavonoid glycoside monomer isolated and purified from the dried aerial parts of Epimedium brevicornum Maxim, commonly known as Horny Goat Weed. As the dominant functional marker ingredient of traditional Epimedium herb, Icariin features a unique flavonoid glycoside molecular structure and delivers multiple high-value pharmacological properties, including bone metabolism regulation, immune enhancement, anti-oxidation, anti-inflammation and physiological vitality improvement. We provide two premium industrial grades: Research Grade 98% HPLC and Premium Functional Grade 99% HPLC, produced through standardized herbal raw material sorting, low-temperature alcohol reflux extraction, multi-stage macroporous resin gradient impurity removal, preparative HPLC fine purification and low-temperature recrystallization. The fully enclosed dust-free production system thoroughly eliminates plant fibers, miscellaneous flavonoids, heavy metals and solvent residues, obtaining single-component high-purity Icariin powder with stable structural activity and zero experimental interference. Widely recognized in modern phytopharmacology, Epimedium Icariin has become a core tool compound for bone metabolism and endocrine research, as well as a mainstream high-value raw material for men’s health care, bone-protection supplements and anti-aging functional products.
Different from ordinary crude Epimedium extracts with mixed flavonoid components and unstable content ratios, our purified single-component Epimedium Icariin possesses definite molecular configuration, controllable bioavailability and standardized pharmacological efficacy, ensuring highly repeatable experimental data and consistent finished product effects. In bone health regulation, Icariin effectively promotes osteoblast proliferation and differentiation, inhibits excessive osteoclast activation and bone mineral loss, improves bone density and bone microstructure, and exerts significant auxiliary intervention effects on osteoporosis and bone metabolism disorders. Its targeted bone-protective mechanism makes it irreplaceable in bone pharmacology research and bone-health functional product development.
In terms of immune regulation and anti-oxidation, high-purity Epimedium Icariin scavenges intracellular reactive oxygen species, blocks lipid peroxidation chain reactions, reduces oxidative stress damage to tissues and organs, and delays cellular senescence. It also regulates immune cell activity and cytokine secretion, enhances systemic immune defense capability, and improves sub-health conditions caused by long-term fatigue and low immunity. For endocrine and physiological regulation, Icariin gently modulates related hormone levels, improves physiological vitality, relieves physical fatigue, and supports human body physiological balance and daily vitality maintenance. In addition, it delivers stable anti-inflammatory activity by inhibiting the release of pro-inflammatory factors, relieving chronic low-grade inflammatory responses in the body.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our high-purity Epimedium Extract (Icariin) adopts a full-process low-temperature light-shielded closed production process. Strict parameter control is implemented during extraction and purification to avoid oxidative denaturation of active flavonoid glycoside structures, completely retaining the original bone-protective, immune-enhancing and anti-aging biological activity. The finished product presents uniform light yellow to brownish-yellow fine crystalline powder with delicate texture, no agglomeration, no discoloration and no peculiar smell, fully compliant with international food, health product and laboratory reagent grade standards.
Every batch of Epimedium Icariin undergoes comprehensive multi-dimensional quality verification, including HPLC high-precision purity detection, NMR structural identification, mass spectrometry molecular weight confirmation and cell-level biological activity evaluation. Ultra-low residual impurities and excellent batch-to-batch consistency guarantee stable pharmacological activity and reliable experimental repeatability. With good solubility in conventional organic solvents and superior biocompatibility in cell culture and in vivo animal models, our Epimedium Extract adapts to diverse scientific research and industrial formulation scenarios. We support long-term bulk stable supply, customized purity grades and professional light-proof moisture-proof vacuum packaging, providing cost-effective high-quality Epimedium Icariin raw materials for global research institutions, pharmaceutical laboratories, health supplement manufacturers and functional food enterprises.
Functions & Benefits
Professional Bone Metabolism Regulation & Anti-Osteoporosis
High-purity Icariin actively promotes osteoblast growth and differentiation, suppresses osteoclast overactivation and bone mineral loss, optimizes bone microstructure and improves bone density. It provides targeted bone protection effects, serving as the core active ingredient for bone metabolism research and osteoporosis auxiliary conditioning products.
Immune Enhancement & System Immune Balance
Epimedium Icariin regulates the proliferation and activity of immune cells, promotes reasonable cytokine secretion, enhances the body’s innate immune defense capability, and improves low immunity and fatigue sub-health, maintaining long-term systemic immune homeostasis.
Powerful Antioxidant & Anti-Aging Activity
The unique flavonoid glycoside structure scavenges excess intracellular free radicals, inhibits lipid peroxidation and oxidative tissue damage, delays cell and organ senescence progression, and provides comprehensive anti-aging protection for the human body.
Physiological Vitality Improvement & Fatigue Relief
As a classic plant-derived vitality-regulating ingredient, Icariin gently modulates physiological endocrine balance, relieves physical fatigue, improves daily vitality and physical endurance, and is widely applied in men’s health and vitality-supporting functional formulas.
Chronic Anti-Inflammatory & Tissue Protection
Icariin inhibits the activation of inflammatory signaling pathways and reduces the release of pro-inflammatory factors, effectively relieving chronic low-grade inflammation in the body, reducing inflammatory tissue damage and protecting multiple organ physiological functions.
Ultra-High Single Component Purity & Zero Experimental Interference
Adopting multi-stage HPLC fine purification and low-temperature recrystallization technology, our Epimedium Icariin completely removes miscellaneous flavonoids, plant impurities and macromolecular residues. 98%–99% ultra-high single-component purity eliminates ingredient interference, ensuring accurate experimental results and standardized industrial formulation efficacy.
High Biological Safety & Wide Formulation Compatibility
Derived from natural edible medicinal Epimedium herb with mild properties and low toxicity, Epimedium Icariin possesses excellent human body biocompatibility and stable formula adaptability, suitable for long-term application in scientific research, functional food and health supplement industries.
Applications
Bone Metabolism & Osteoporosis Pharmacology Research
Widely used as a standard flavonoid monomer for osteoblast/osteoclast cell model experiments, bone density regulation and bone metabolism mechanism research, serving as a core experimental tool in bone pharmacology studies.
Immune Regulation & Anti-Fatigue Mechanism Study
Applied in immune cell activity detection, inflammatory factor regulation and physical fatigue intervention research, supporting sub-health conditioning and immune-enhancing functional ingredient development.
Antioxidant & Anti-Aging Pharmacological Research
Key experimental compound for free radical scavenging, lipid oxidation inhibition and cellular senescence research, widely used in natural antioxidant and anti-aging mechanism exploration.
Men’s Health & Physiological Vitality Functional Formulation
Used as a core functional additive for vitality enhancement, physical fatigue relief and endocrine balance health supplements, widely applied in high-end men’s health functional product production.
Bone-Protection & Anti-Aging Functional Food
Widely added in bone-strengthening, anti-osteoporosis and anti-fatigue functional foods, providing safe and efficient natural flavonoid active nutrition for daily body health maintenance.
University Lab Teaching & Pharmacological Demonstration
Supplied as standard high-purity Epimedium Icariin reagent for natural herbal flavonoid pharmacology, bone metabolism and immune regulation teaching, ensuring accurate and stable experimental data for academic research and teaching demonstration.
FAQ
Q1: What is Epimedium Extract (Icariin) used for?
A: Epimedium Icariin is the core active flavonoid monomer of Epimedium herb, mainly used in bone metabolism, immune regulation and antioxidant pharmacological research, as well as core raw material for men’s health, bone protection and anti-fatigue health supplements.
Q2: What is the advantage of high-purity Icariin over ordinary Epimedium powder?
A: Ordinary Epimedium powder or crude extract contains multiple mixed flavonoids and plant impurities with unstable efficacy. Our 98%/99% high-purity Icariin is a single purified monomer with definite structure, pure efficacy and no impurity interference, suitable for precise scientific research and high-end standardized formulation.
Q3: What are your product advantages?
A: Our Epimedium Icariin is refined by multi-stage preparative HPLC to reach 98%–99% ultra-high purity, free of miscellaneous flavonoid impurities and solvent residues. It features stable bone-protective, immune-enhancing and antioxidant activity, excellent batch consistency and high experimental repeatability, fully compliant with international industrial and laboratory standards.
Q4: How to store Epimedium Icariin correctly?
A: Epimedium Icariin is sensitive to high temperature, strong light and humid air, prone to oxidative deactivation. It must be vacuum-sealed and stored in low-temperature, dry and dark conditions to maintain complete biological activity within the 24-month shelf life.
Q5: What does high-purity Epimedium Extract look like?
A: Standard high-purity Epimedium Icariin is uniform light yellow to brownish-yellow fine crystalline powder at room temperature, with faint herbal aroma, stable texture, no caking and no discoloration under standard sealed storage.
Q6: Can I get free Epimedium Icariin samples?
A: Yes, we provide free Epimedium Extract (Icariin) samples for academic research, pharmacological efficacy verification and product formula testing. Bulk orders support customized purity and exclusive light-proof vacuum packaging to meet scientific research and industrial production demands.
