Product Introduction
| Item | Specification |
| Product Name | EGCG / Epigallocatechin Gallate |
| Synonyms | (-)-Epigallocatechin 3-gallate; Epigallocatechin gallate; Green Tea Catechin; EGCG Polyphenol |
| CAS Number | 989-51-5 |
| Molecular Formula | C₂₂H₁₈O₁₁ |
| Molecular Weight | 458.37 g/mol |
| Appearance | Off-white to pale yellow fine crystalline powder, faint natural green tea aroma, stable texture, no caking under sealed dry and dark storage conditions |
| Purity (HPLC) | ≥98.0% / ≥99.0% (Research Grade / Premium Functional Grade, customizable) |
| Loss on Drying | ≤ 0.2% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / NMR / Mass Spectrometry / IR Spectrum / Biological Activity Assay |
| Production Method | Green Tea Leaf Extraction + Macroporous Resin Gradient Separation + Preparative HPLC Purification + Low-Temperature Recrystallization |
| Melting Point | 212–214°C (lit.) |
| Boiling Point | 905.5°C at 760 mmHg (Predicted) |
| Density | 1.72 g/cm³ at 25°C |
| Flash Point | 325.2°C |
| Solubility | Freely soluble in methanol, ethanol, DMSO and acetone; soluble in hot water, slightly soluble in cold water; insoluble in petroleum ether; sensitive to high temperature, strong light and alkaline environment, prone to oxidative browning |
| Core Feature | Predominant bioactive catechin monomer in green tea, ultra-high activity natural polyphenol, superior antioxidant capacity, multi-target metabolic and inflammatory regulatory functions, dual research and industrial application value |
| Package | 1g/5g/10g amber sealed bottle, 100g/1kg vacuum drum; moisture-proof & light-proof vacuum packaging, customized specifications supported |
| Storage | Store in vacuum-sealed, low-temperature, dry and dark conditions; avoid high temperature, strong light and alkaline environment to prevent phenolic oxidation and activity attenuation |
| Shelf Life | 24 months under standard sealed low-temperature dark storage |
Product Description
EGCG (Epigallocatechin Gallate, CAS 989-51-5) is the most abundant and biologically active single catechin monomer purified from the fresh leaves of Camellia sinensis, widely recognized as the core functional ingredient of green tea polyphenols. Featuring a unique gallated catechin molecular structure with multiple active phenolic hydroxyl groups, EGCG delivers far stronger antioxidant, anti-inflammatory and metabolic regulatory activities than other tea catechins and conventional plant antioxidants. We supply two premium grades: Research Grade 98% HPLC and Premium Functional Grade 99% HPLC, manufactured through standardized green tea raw material solvent extraction, multi-stage macroporous resin gradient impurity removal, preparative HPLC precision purification and low-temperature recrystallization. The fully enclosed low-temperature production system thoroughly removes miscellaneous catechin impurities, plant fibers, heavy metals and solvent residues, obtaining single-component high-purity EGCG with stable structural activity and zero experimental interference. As a classic natural polyphenol tool compound, EGCG is extensively applied in oxidative stress pharmacological research, lipid metabolism regulation studies, anti-photoaging cosmetic formulation and high-value functional health supplement production.
Different from crude green tea extracts containing mixed catechin components (EGC, ECG, Caffeine and miscellaneous impurities), our purified single-component EGCG possesses definite molecular structure, controllable bioavailability and standardized pharmacological efficacy, ensuring highly repeatable experimental data and stable finished product effects. The multi-phenolic hydroxyl structure of EGCG enables superior free radical scavenging ability, which can efficiently eliminate intracellular reactive oxygen species, block lipid peroxidation chain reactions, protect cell membrane and mitochondrial integrity, and reduce cumulative oxidative damage of tissues and organs. Its antioxidant activity is significantly higher than vitamin C, vitamin E and ordinary plant polyphenols, making it a gold-standard raw material for natural anti-aging and antioxidant research.
In anti-inflammatory and metabolic regulation fields, EGCG targets and inhibits NF-κB, MAPK and other core inflammatory signaling pathways, significantly reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-6 and IL-1β, effectively relieving chronic low-grade inflammation in the body. For lipid and energy metabolism, EGCG inhibits de novo lipid synthesis, accelerates fatty acid oxidative decomposition, optimizes blood lipid levels and improves metabolic disorders, providing reliable support for weight management and cardiovascular health research. In skincare applications, EGCG resists UV-induced skin oxidative damage, inhibits abnormal melanin deposition, relieves skin inflammatory redness and dullness, and delays photoaging, becoming a core functional additive for high-end antioxidant and brightening cosmetic formulas.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our high-purity EGCG adopts a dust-free, light-shielded and low-temperature closed production workshop. Strict parameter control is implemented throughout the purification process to avoid oxidative deterioration of active phenolic groups, completely retaining the original antioxidant, anti-inflammatory and metabolic regulatory biological activity. The finished product presents uniform pale yellow fine crystalline powder with delicate texture, no agglomeration, no discoloration and no peculiar smell, fully compliant with international food, cosmetic and laboratory reagent grade standards.
Every batch of EGCG undergoes comprehensive multi-dimensional quality verification, including HPLC high-precision purity detection, NMR structural identification, mass spectrometry molecular confirmation and cell-level biological activity evaluation. Ultra-low residual impurities and excellent batch-to-batch consistency guarantee stable pharmacological activity and reliable experimental repeatability. With good solubility in common organic solvents and superior biocompatibility in cell culture and in vivo animal models, our EGCG adapts to diverse scientific research and industrial formulation scenarios. We support long-term bulk stable supply, customized purity grades and professional light-proof moisture-proof vacuum packaging, providing cost-effective high-quality EGCG raw materials for global research institutions, pharmaceutical laboratories, cosmetic manufacturers and functional health food enterprises.
Functions & Benefits
Ultra-High Activity Natural Antioxidant & Anti-Aging
Rich active phenolic hydroxyl groups endow EGCG with powerful free radical scavenging capacity, efficiently eliminating intracellular reactive oxygen species and blocking lipid peroxidation damage. It reduces systemic oxidative stress, delays cell and organ senescence progression, and provides long-lasting comprehensive antioxidant protection, with superior efficacy over conventional natural antioxidants.
Multi-Target Anti-Inflammatory & Inflammatory Balance Regulation
EGCG inhibits the activation of multiple inflammatory signaling pathways and reduces the release of pro-inflammatory factors, effectively relieving acute inflammatory responses and chronic low-grade inflammation in the body. It improves inflammatory tissue damage, regulates immune inflammatory balance, and provides stable anti-inflammatory support for physiological health maintenance.
Lipid Metabolism Regulation & Cardiovascular Protection
This natural catechin monomer inhibits endogenous lipid synthesis, accelerates fatty acid catabolism, optimizes blood lipid metabolism indicators, and reduces vascular lipid deposition. It protects vascular endothelial cell integrity, improves microcirculation, and serves as a core raw material for metabolic regulation and cardiovascular health functional products.
Anti-Photoaging & Skin Brightening Skincare Effect
EGCG resists ultraviolet-induced skin oxidative damage and photoaging, inhibits abnormal melanin proliferation and deposition, fades skin dullness and yellowish tone, and relieves inflammatory redness and sensitivity. It is a high-end natural functional additive for antioxidant, repairing and brightening cosmetic formulations.
Immune Modulation & System Physiological Maintenance
EGCG regulates immune cell activity and cytokine secretion, balances systemic immune responses, enhances the body’s antioxidant defense and immune regulation capabilities, and improves sub-health state caused by long-term oxidative stress and inflammatory imbalance.
Ultra-High Single Component Purity & Zero Experimental Interference
Adopting multi-stage HPLC fine purification and low-temperature recrystallization technology, our EGCG completely removes miscellaneous tea catechins, caffeine and plant impurities. 98%–99% ultra-high single-component purity eliminates ingredient interference, ensuring accurate experimental results and standardized industrial formulation efficacy.
High Biological Safety & Wide Application Compatibility
Derived from edible natural green tea leaves with low toxicity and excellent human body biocompatibility, EGCG maintains stable biological activity in complex formulas and experimental environments, suitable for long-term application in scientific research, functional food, healthcare supplements and cosmetics.
Applications
Oxidative Stress & Antioxidant Pharmacology Research
Widely used as a standard catechin monomer for intracellular free radical scavenging, lipid oxidation inhibition and cellular anti-aging mechanism research, serving as a core experimental tool in oxidative pharmacology and cell biology studies.
Inflammatory & Immune Regulatory Mechanism Study
Applied in inflammatory signaling pathway exploration, pro-inflammatory factor regulation and immune balance research, supporting chronic inflammation disease mechanism analysis and related functional ingredient development.
Lipid Metabolism & Cardiovascular Health Research
Key experimental compound for lipid synthesis inhibition, fat metabolism regulation and vascular endothelial protection research, widely used in metabolic disorder intervention and cardiovascular health-related product development.
High-End Antioxidant & Repairing Cosmetic Formulation
Used as a core functional additive for anti-photoaging, antioxidant, soothing and brightening skincare products, effectively improving skin oxidative aging, dullness and inflammatory sensitivity for high-end natural cosmetic production.
Metabolic Conditioning & Antioxidant Functional Food
Widely added in weight management, lipid-lowering and anti-aging health supplements and functional foods, providing safe and efficient natural polyphenol nutrition for daily metabolic and antioxidant health maintenance.
University Lab Teaching & Pharmacological Demonstration
Supplied as standard high-purity EGCG reagent for natural tea polyphenol pharmacology, antioxidant and anti-inflammatory mechanism teaching, ensuring accurate and stable experimental data for academic research and teaching demonstration.
FAQ
Q1: What is EGCG mainly used for?
A: EGCG is the most active green tea polyphenol monomer, mainly applied in antioxidant, anti-inflammatory and lipid metabolism pharmacological research, as well as core raw material for anti-aging cosmetics, metabolic conditioning health supplements and functional food manufacturing.
Q2: What is the difference between pure EGCG and ordinary green tea extract?
A: Ordinary green tea extract is a mixed system containing multiple catechins, caffeine and impurities with unstable component ratio. Our high-purity EGCG is a single independent monomer with definite structure, pure efficacy and no miscellaneous interference, suitable for precise scientific research and high-standard product formulation.
Q3: What are your product advantages?
A: Our EGCG is refined by multi-stage preparative HPLC to reach 98%–99% ultra-high purity, free of miscellaneous catechin impurities and solvent residues. It features ultra-strong stable antioxidant and anti-inflammatory activity, excellent batch consistency and high experimental repeatability, fully compliant with international industrial and laboratory standards.
Q4: How to store EGCG correctly?
A: EGCG is sensitive to high temperature, strong light and alkaline environments, easy to oxidize and turn brown and deactivate. It must be vacuum-sealed and stored in low-temperature, dry and dark conditions to maintain complete biological activity within the 24-month shelf life.
Q5: What does high-purity EGCG look like?
A: Standard high-purity EGCG is uniform off-white to pale yellow fine crystalline powder at room temperature, with faint natural green tea fragrance, stable texture, no caking and no discoloration under standard sealed storage.
Q6: Can I get free EGCG samples?
A: Yes, we provide free EGCG samples for academic research, pharmacological efficacy verification and product formula testing. Bulk orders support customized purity and exclusive light-proof vacuum packaging to meet scientific research and industrial production demands.
