Product Introduction
| Item | Specification |
| Product Name | Daidzein |
| Synonyms | 7-Hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; Soy isoflavone aglycone; Daidzeol |
| CAS Number | 486-66-8 |
| Molecular Formula | C₁₅H₁₀O₄ |
| Molecular Weight | 254.24 g/mol |
| Appearance | Off-white to pale yellow fine crystalline powder, odorless, stable texture, no caking under sealed dry and dark storage conditions |
| Purity (HPLC) | ≥98.0% / ≥99.0% (Research Grade / Premium Functional Grade, customizable) |
| Loss on Drying | ≤ 0.2% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / NMR / Mass Spectrometry / IR Spectrum / Biological Activity Assay |
| Production Method | Pueraria Root & Soybean Raw Material Extraction + Enzymatic Hydrolysis + Macroporous Resin Purification + Preparative HPLC + Low-Temperature Recrystallization |
| Melting Point | 315–323°C (lit.) |
| Boiling Point | 512.9°C at 760 mmHg (Predicted) |
| Density | 1.42 g/cm³ at 25°C |
| Flash Point | 198.8°C |
| Solubility | Slightly soluble in water, soluble in hot ethanol, methanol, DMSO, acetone; insoluble in petroleum ether and chloroform; stable in dry dark place, sensitive to strong ultraviolet irradiation and high temperature |
| Core Feature | Typical aglycone isoflavone with natural phytoestrogen activity, core functional marker of Pueraria and soybean extract, dual value for endocrinology research and women’s health raw material |
| Package | 1g/5g/10g amber sealed bottle, 100g/1kg vacuum drum; moisture-proof & light-proof vacuum packaging, customized specifications supported |
| Storage | Store in vacuum-sealed, low-temperature, dry and dark conditions; avoid high temperature, strong light and humid air to prevent oxidative degradation and activity attenuation |
| Shelf Life | 24 months under standard sealed low-temperature dark storage |
Product Description
Daidzein (CAS 486-66-8) is a natural aglycone isoflavone monomer mainly isolated from dried Pueraria lobata root and soybean seeds, widely known as classic plant-derived phytoestrogen ingredient. Different from glycosidic daidzin, Daidzein owns superior intestinal absorption efficiency and higher biological availability after enzymatic hydrolysis removing sugar moiety. Our factory provides two standard grades: Research Grade ≥98% HPLC and Premium Functional Grade ≥99% HPLC, manufactured by raw herb crushing, alcohol reflux extraction, biological enzymatic cleavage, macroporous resin gradient separation and high-efficiency preparative HPLC plus low-temperature recrystallization. The whole purification workflow thoroughly removes genistein impurity, plant polysaccharide, protein residue and heavy metal pollutants, achieving single-component refined powder compliant with global pharmacopoeia and cosmetic raw material specifications. With selective estrogen receptor binding, free radical scavenging, vascular protection and osteoblast proliferation promotion, Daidzein becomes essential test compound for endocrinology research and mainstream raw material for menopause-support healthcare supplements and anti-aging skincare.
Unlike mixed crude soybean or kudzu extracts containing multiple isoflavone blends, our pure Daidzein features clear molecular construction, defined action targets and controllable biological efficacy, guaranteeing repeatable experimental outcomes and standardized formulation effect. As selective phytoestrogen, Daidzein moderately combines with ERα and ERβ receptors to bidirectionally regulate endocrine level, alleviating menopausal hot flashes, endocrine disorder and ovarian function decline induced by endogenous estrogen fluctuation. For antioxidant performance, abundant phenolic hydroxyl groups effectively clear intracellular reactive oxygen radicals, restrain lipid peroxidation chain reaction, stabilize cell membrane structure and mitigate oxidative aging damage on tissue and organs.
In cardiovascular protection field, Daidzein improves blood lipid metabolism, lowers LDL deposition on vascular wall, protects vascular endothelial cells and inhibits abnormal platelet aggregation, helping reduce atherosclerosis risk and supporting vessel health maintenance. Meanwhile, Daidzein accelerates osteoblast differentiation and suppresses osteoclast overactivation, effectively slowing bone mineral loss and improving bone density for osteoporosis auxiliary research and related healthcare development. In cosmetic industry, Daidzein relieves hormone-related dull skin, improves skin elasticity and inhibits UV-triggered oxidative aging, applied in anti-wrinkle and balancing skincare formulas.
Produced by Shaanxi BAISFU Bio-Engineering Co., Ltd., Daidzein adopts fully closed dust-free and light-shielded production workshop. Strict low-temperature control during extraction and purification prevents phenolic structure oxidation and molecular deactivation, fully retaining original phytoestrogen and antioxidant bioactivity. Final finished powder presents uniform pale yellow fine crystal without lump or discoloration, free of foreign plant debris and residual organic solvent.
Each production batch passes full spectrum quality inspection including HPLC purity test, NMR structural confirmation, MS molecular weight verification and cellular activity bioassay. Ultra-low impurity content and consistent batch-to-batch property secure stable experimental data and finished product efficacy. With favorable solubility in conventional organic solvents and outstanding biocompatibility in cell culture and animal in-vivo trials, our Daidzein fits diversified lab research and industrial production requirements. We sustain long-term bulk inventory supply, customizable purity specification and customized light-resistant vacuum packing, supplying cost-effective high-purity Daidzein raw material for global research institutes, pharmaceutical R&D labs, health supplement factories and cosmetic manufacturers.
Functions & Benefits
Bidirectional Phytoestrogen Endocrine Regulation
Daidzein selectively binds human estrogen receptors to balance endogenous hormone level, ease menopausal endocrine discomfort and ovarian function recession, core experimental monomer for female endocrine pharmacology and menopause healthcare raw material development.
Powerful Antioxidant & System Anti-Aging
Active phenolic groups rapidly clear excess free radicals inside cells, block lipid peroxidation damage and slow cell senescence progression, providing persistent antioxidant protection for organs and skin tissue.
Cardioprotective & Blood Lipid Modulation
Optimizes lipid metabolism indexes, protects vascular endothelium and prevents abnormal platelet aggregation, reduces vascular lipid plaque accumulation for cardiovascular protection research and related functional food development.
Bone Protection & Anti-Osteoporosis Activity
Promotes osteoblast proliferation while restraining excessive osteoclast activity, slows bone mineral loss and enhances bone density, widely used in bone metabolism study and bone-health supplementary products.
Hormone-Balanced Anti-Aging Skin Care
Improves hormone-caused skin dryness and dullness, alleviates UV oxidative damage, lifts skin elasticity and fades fine lines as premium natural additive for balancing and anti-photoaging skincare formulations.
Ultra-High Single Component Purity
Multi-step HPLC refining and recrystallization eliminate genistein, daidzin and plant heterologous impurities, 98%~99% high purity avoids impurity interference for precision pharmacological test and high-end formula production.
High Biological Safety & Wide Formula Compatibility
Derived from edible soybean and medicinal Pueraria root with low toxic risk and excellent biocompatibility, keeps stable activity in lab test and finished product formulas for multiple industry applications.
Applications
Endocrine & Menopause Pharmacology Research
Core standard isoflavone monomer for estrogen receptor binding experiment, menopausal syndrome mechanism exploration and female endocrine disease drug screening research.
Cardiovascular & Lipid Metabolism Research
Applied in vascular endothelial protection, blood lipid regulation and anti-atherosclerosis pharmacological trials for cardiovascular health related research and functional ingredient development.
Bone Metabolism & Anti-Osteoporosis Study
Common experimental compound for osteoblast/osteoclast cell model study and in-vivo bone density test, supporting osteoporosis prevention related research and health product exploitation.
High-End Functional Cosmetic Raw Material
Added into balancing, anti-aging and antioxidant skincare formulas to improve hormone imbalance induced skin aging, widely used for high-end natural cosmetics production.
Women’s Health Functional Food & Supplement
Key functional additive for menopause conditioning, bone protection and anti-aging health supplements, popular raw material in global plant-derived healthcare industry.
University Lab Teaching & Pharmacology Demonstration
Supplied as certified high-purity reference reagent for natural isoflavone pharmacology teaching and experimental demonstration in biology and pharmacy majors.
FAQ
Q1: What is Daidzein mainly used for?
A: Daidzein is natural aglycone isoflavone mainly used for endocrine, cardiovascular and bone protection pharmacological research, as well as raw material for menopause healthcare supplements and anti-aging cosmetics.
Q2: Difference between Daidzein and Daidzin?
A: Daidzin is glycoside type with sugar group, poor absorption; Daidzein is aglycone after removing glycosyl via enzymolysis, much higher bioavailability, preferred for precise research and high-end finished products.
Q3: What are your product advantages?
A: Our Daidzein reaches 98%/99% high purity by HPLC purification, low heteroisoflavone impurity, stable phytoestrogen activity, consistent batch quality and high experimental repeatability matching international industrial standard.
Q4: How to properly store Daidzein?
A: Daidzein is sensitive to strong light, high temperature and moist air, must be vacuum sealed and preserved under cool dry dark environment to maintain full activity within 24 months shelf life.
Q5: Appearance of high purity Daidzein?
A: Standard high purity Daidzein is pale yellow fine crystalline powder at room temperature, odorless, free from agglomeration and discoloration under normal sealed preservation.
Q6: Can free sample be provided?
A: Yes, free Daidzein samples are available for academic research, efficacy verification and formulation trial; bulk order supports customized purity and exclusive moisture-proof vacuum packaging.
