Product Introduction
| Item | Specification |
| Product Name | Anabasine |
| Synonyms | Neonicotine; 2-(3-Pyridyl)piperidine |
| CAS Number | 494-52-0 |
| Molecular Formula | C₁₀H₁₄N₂ |
| Molecular Weight | 162.23 g/mol |
| Appearance | Colorless transparent viscous liquid, gradually darkens to light yellow when exposed to air |
| Purity (HPLC/GC) | ≥98.0% / ≥99.0% (Research Grade / Industrial Grade, customizable) |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / GC / NMR / Mass Spectrometry |
| Production Method | Natural Plant Extraction & Multi-Stage Vacuum Rectification Purification / Synthetic Refining |
| Melting Point | 9°C (lit.) |
| Boiling Point | 270–272°C at 760 mmHg |
| Density | 1.045 g/cm³ at 25°C |
| Flash Point | 93°C |
| Solubility | Fully miscible with water, soluble in ethanol, methanol, DMSO and most organic solvents, excellent polar solvent compatibility |
| Core Feature | Natural pyridine alkaloid, nicotine structural isomer, dual efficacy of biological insecticidal and neurological pharmacological activity |
| Package | 1g/5g/10g sealed fluorinated bottle, 100g/1kg packaging; custom specification available |
| Storage | Store in sealed, dark, dry and low-temperature environment; avoid air contact, strong light and high temperature to prevent oxidation discoloration |
| Shelf Life | 24 months under standard sealed storage conditions |
Product Description
Our Anabasine is a high-purity natural pyridine alkaloid with stable monomer activity, available in 98% and 99% premium grades. Anabasine (CAS 494-52-0), also known as Neonicotine or 2-(3-Pyridyl)piperidine, is a classic bioactive alkaloid isolated from Anabasis aphylla and tobacco plants, serving as a structural isomer and functional analog of nicotine. Different from polyphenol skincare ingredients such as Hamamelitannin and Thymoquinone focused on anti-inflammatory and antioxidant efficacy, and differentiated from terpenoid products like Borneol and Terpinen-4-ol positioned for fragrance synthesis and antisepsis, Anabasine is professionally positioned in biological pesticide raw materials and neuropharmacological research, featuring unique nicotinic acetylcholine receptor agonist activity and broad-spectrum insecticidal properties. As a professional bulk Anabasine supplier, we provide high-purity, low-impurity, stable-activity alkaloid monomers for global biopesticide manufacturers, biomedical research laboratories and fine chemical synthesis enterprises.
Anabasine has irreplaceable differentiated advantages in the field of natural bioactive alkaloids. Compared with nicotine, it exhibits milder and more stable neuroactivity, with significant cholinesterase inhibitory effect and targeted insect paralysis activity. Its unique pyridine-piperidine fused ring structure enables it to efficiently act on insect nervous systems, resulting in excellent contact and stomach toxicity against agricultural pests, while possessing lower mammalian toxicity than traditional chemical pesticides. In pharmacological research, Anabasine acts as a key tool compound for studying nicotinic receptor signaling pathways, tobacco exposure biomarkers, and neurotoxicological mechanisms, occupying an important position in neuroscience and toxicology research. In addition, it serves as a core intermediate for the derivation and synthesis of new neonicotinoid pesticide compounds, supporting the innovation and upgrading of green biological pesticides.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Anabasine adopts advanced natural plant directional extraction combined with multi-stage high-vacuum precision rectification and purification technology. We select high-quality Anabasis aphylla raw materials with stable alkaloid content, remove plant pigments, macromolecular impurities, residual wax and heterologous alkaloid mixtures through gradient separation and precise distillation, and completely retain the pure monomer structure and biological activity of Anabasine. The whole production process strictly controls temperature and oxygen isolation to avoid oxidative discoloration and activity attenuation, eliminating the defects of low purity, impure odor and unstable efficacy of crude plant extracts. The finished product features uniform liquid state, stable chemical properties and ultra-low impurity content, fully complying with industrial biopesticide grade and scientific research grade quality standards.
Every batch of Anabasine undergoes strict multi-dimensional quality inspection, including HPLC/GC high-precision purity detection, NMR structural identification, mass spectrometry molecular verification and impurity residue analysis. It ensures ultra-high single-component purity, no heterologous alkaloid interference and stable batch consistency. The product has excellent water solubility and organic solvent compatibility, easy to formulate and modify, maintaining long-term stable biological activity under standardized storage conditions. All technical indicators meet international natural alkaloid standards and biopesticide raw material specifications, supporting safe and efficient large-scale industrial application and high-precision scientific research experiments.
We maintain sufficient inventory and complete qualification documents for bulk Anabasine supply. Whether you need high-activity raw materials for green biopesticide formulation, standard monomers for neuropharmacological and toxicological research, or key intermediates for neonicotinoid derivative synthesis, our high-purity Anabasine is a high-cost-performance and high-value natural alkaloid raw material choice for global buyers.
Functions & Benefits
Broad-Spectrum Biological Insecticidal Activity (Core Benefit)
Anabasine is a classic natural botanical insecticidal alkaloid. It targets the nervous system of pests, inhibits cholinesterase activity, causes nerve conduction block and pest paralysis and death. It has broad-spectrum killing and inhibitory effects on various agricultural and garden pests, featuring high efficiency, low residue and environmental friendliness, which is an ideal raw material for green biological pesticide preparation.
Nicotinic Receptor Agonist & Neuropharmacological Activity
As a structural analog of nicotine, Anabasine can specifically activate nicotinic acetylcholine receptors and induce depolarizing block of nerve transmission. It is a core tool compound for studying neuronal signal transduction, neurotoxicity mechanisms and nicotine receptor pharmacological characteristics, supporting in-depth neuroscience research.
Tobacco Exposure Biomarker Detection Value
Anabasine exists in trace amounts in tobacco smoke and is a specific biomarker for evaluating human tobacco exposure. With high detection specificity and sensitivity, it is widely used in clinical toxicology detection, second-hand smoke exposure assessment and tobacco-related health research.
High-Purity Monomer & Derivative Synthesis Value
High-purity Anabasine has stable molecular structure and high reaction activity, serving as an important fine chemical intermediate for the synthesis of new neonicotinoid pesticides and alkaloid derivatives. It supports structural modification and efficacy optimization of green pesticide molecules.
Excellent Solubility & Formula Adaptability
Anabasine is fully miscible with water and soluble in various polar organic solvents, with excellent formula compounding performance. It can be easily prepared into aqueous formulations, emulsions and solvent formulations, adapting to diverse biopesticide processing and experimental application scenarios.
Stable Batch Quality & Low Impurity
Purified and refined Anabasine eliminates miscellaneous alkaloid impurities and plant-derived interfering components. It features accurate monomer content, stable biological activity and zero batch difference, ensuring consistent efficacy of downstream pesticide products and reliable experimental data repeatability.
Applications
Green Biological Pesticide Manufacturing
Anabasine is widely used in the formulation of high-efficiency low-residue botanical pesticides. It is suitable for pest control in organic agriculture, garden planting and forest protection, replacing part of synthetic chemical pesticides, reducing pesticide residue pollution, and conforming to green agricultural development trends.
Neuropharmacology & Toxicological Research
Served as a standard research monomer for nicotinic receptor mechanism research, neurotoxicity evaluation and cholinesterase inhibitor experiments. It is commonly used in university laboratories, pharmaceutical research institutions and toxicology testing agencies for related pharmacological and safety studies.
Tobacco Exposure & Clinical Detection Research
Applied in biomarker detection of tobacco smoke exposure, second-hand smoke hazard assessment and tobacco-related disease mechanism research. It provides accurate quantitative support for clinical health monitoring and environmental toxicology research.
Fine Chemical & Pesticide Intermediate Synthesis
Used as a key alkaloid intermediate for the structural derivation and synthesis of new neonicotinoid compounds. It supports the research and development of high-efficiency, low-toxicity and high-selectivity green pesticide new varieties.
Laboratory Scientific Research & Custom Experiment
Provided as high-purity standard Anabasine monomer for natural alkaloid activity verification, pesticide efficacy debugging and neuropharmacological mechanism exploration, supporting customized scientific research and new product development.
FAQ
Q1: What is Anabasine used for?
A: Anabasine is a high-value natural pyridine alkaloid. It is mainly used for green biological pesticide preparation, neuropharmacological and toxicological research, tobacco exposure biomarker detection, and fine chemical intermediate synthesis of neonicotinoid derivatives.
Q2: What is the difference between Anabasine and Nicotine?
A: Anabasine is a structural isomer of nicotine. It has similar nicotinic receptor activity but milder neurotoxicity and more stable insecticidal efficacy. It is more suitable for green pesticide development and long-term pharmacological research than nicotine, with higher application safety.
Q3: What are the core advantages of Anabasine?
A: Anabasine features natural plant source, broad-spectrum high-efficiency insecticidal activity, stable neuropharmacological properties, excellent water solubility and low residual characteristics. It is a rare dual-functional natural alkaloid integrating agricultural pest control and scientific research value.
Q4: How to store Anabasine correctly?
A: Anabasine is easy to oxidize and darken when exposed to air and strong light. It must be stored in sealed, dark, dry and low-temperature conditions. Isolated air storage can effectively prevent discoloration and activity attenuation, ensuring 24 months of valid shelf life.
Q5: What is the appearance of high-purity Anabasine?
A: High-purity Anabasine is a colorless transparent viscous liquid at room temperature. It will gradually turn light yellow after long-term exposure to air, with pure characteristic alkaloid odor and no peculiar impurities.
Q6: Can I get free Anabasine samples for testing?
A: Yes, we provide free Anabasine samples for pesticide formula debugging, pharmacological experiment research and derivative synthesis tests. Bulk orders support customized purity and packaging to meet industrial production and scientific research needs.
