Product Introduction
| Item | Specification |
| Product Name | Procyanidin |
| Synonyms | Proanthocyanidin; Grape seed extract oligomer |
| CAS Number | 4852-22-6 |
| Molecular Formula | C₃₀H₂₆O₁₃ |
| Molecular Weight | 594.52 g/mol |
| Appearance | Off-white to light brown crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 125–127°C |
| Density | 1.7±0.1 g/cm³ |
| Solubility | Soluble in water, methanol, ethanol and polar solvents, good water solubility for cosmetic and oral formulas |
| Natural Source | Naturally extracted from high-quality grape seeds and pine bark, a high-activity oligomeric flavonoid compound with superior antioxidant potency |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry conditions; avoid high temperature, light exposure and oxidation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Procyanidin powder is a high-purity natural flavonoid active ingredient, available in 98% and 99% HPLC grades. Procyanidin (CAS 4852-22-6), known as is a premium oligomeric proanthocyanidin widely sourced from grape seeds and pine bark. Renowned for its ultra-high antioxidant activity, it outperforms conventional vitamin and polyphenol antioxidants, featuring integrated anti-glycation, anti-inflammatory, free radical scavenging and skin brightening properties. As a classic multi-functional natural active compound, it covers skincare anti-aging, body metabolic regulation and immune protection, serving as a core raw material for high-end antioxidant skincare and oral health supplements. As a professional bulk Procyanidin supplier, we provide high-purity, low-impurity, high-stability procyanidin raw materials for global cosmetic manufacturers, health product brands and scientific research institutions.
Procyanidin belongs to the flavonoid polyphenol family, with completely differentiated functional positioning from tannin ingredients such as Geraniin, Corilagin and Hamamelitannin. Unlike Geraniin’s anti-glycation whitening and metabolic regulation, Corilagin’s anti-fibrosis repair, and Hamamelitannin’s antibacterial soothing advantages, Procyanidin features industry-leading comprehensive antioxidant capacity. It efficiently scavenges multiple types of free radicals in the skin and body, blocks oxidative stress chain reactions, and effectively improves skin photoaging, dullness and sagging caused by long-term oxidation. Its unique oligomeric structure enables excellent transdermal absorption and oral bioavailability, delivering stable and long-lasting anti-aging effects. Meanwhile, it inhibits advanced glycation end products (AGEs) formation, relieves inflammatory damage, protects vascular health, and achieves dual anti-aging effects for both skin and body.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Procyanidin powder adopts low-temperature physical extraction and multi-stage high-precision column chromatography purification technology. We select high-quality mature grape seeds and pine bark raw materials with stable active content, completely remove plant fibers, macromolecular impurities, residual sugars and invalid polymer components through gradient elution purification, and fully retain the complete oligomeric active structure and biological potency of Procyanidin. The entire production process eliminates harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The refined purification technology solves the defects of low activity, impure components and unstable efficacy of ordinary crude grape seed extracts, ensuring uniform powder appearance, high purity and excellent batch consistency for standardized formula development.
Every batch of Procyanidin powder undergoes strict multi-dimensional quality inspection, including HPLC high-precision purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished powder features low impurity content, good solubility in water and polar solvents, mild activity and high safety. All products comply with international cosmetic additive regulations and natural health food safety standards, supporting safe and standardized application in antioxidant anti-aging skincare, oral antioxidant health products and biomedical pharmacological research.
We maintain sufficient inventory and complete qualification documents for bulk Procyanidin supply. Whether you need high-efficiency antioxidant anti-aging active raw materials for skincare formulas, natural free radical-scavenging ingredients for health supplements, or high-purity flavonoid monomers for oxidative stress research, our Procyanidin powder is a cost-effective and high-value bulk raw material choice for global buyers.
Functions & Benefits
Ultra-Strong Antioxidant & Anti-Photoaging (Core Benefit)
Procyanidin delivers powerful DPPH, ABTS and superoxide anion free radical scavenging capacity, effectively blocking skin oxidative stress and lipid peroxidation damage caused by UV radiation and environmental pollution. It reduces skin dullness, yellowish tone and rough texture, delays photoaging and fine line formation, and builds a long-term endogenous antioxidant defense barrier for youthful skin maintenance.
Efficient Anti-Glycation & Anti-Sagging
It significantly inhibits the production of advanced glycation end products (AGEs), improves skin glycation aging problems such as sagging, stiffness and dull yellow complexion. It protects collagen and elastin activity, prevents collagen breakage and aging deposition, and maintains skin elasticity and firmness for anti-aging and anti-wrinkle effects.
Broad-Spectrum Anti-Inflammatory & Barrier Protection
Procyanidin suppresses NF-κB inflammatory signaling pathway, reduces the release of multiple pro-inflammatory factors, relieves mild skin inflammation and external irritation damage. It repairs weakened skin barriers, enhances skin tolerance and environmental stress resistance, and improves sub-health sensitive skin conditions.
Skin Brightening & Uniform Tone
By inhibiting melanin oxidation and sedimentation, Procyanidin fades subtle dullness and pigmentation, evens out skin tone, and restores skin transparency and brightness. It delivers mild and non-irritating brightening effects, suitable for long-term daily whitening and brightening maintenance.
Vascular Protection & Metabolic Health Regulation
As a classic oral antioxidant ingredient, Procyanidin improves microcirculation, enhances vascular elasticity, reduces oxidative damage to blood vessels, and assists in regulating body metabolic balance. It effectively relieves sub-health problems caused by long-term oxidative stress and supports systemic anti-aging maintenance.
Immune Enhancement & Cytoprotection
Modern pharmacological studies confirm that Procyanidin protects cell membranes from oxidative damage, enhances cellular immune activity, reduces free radical damage to internal organs, and exerts excellent anti-fatigue and body-protective effects, with high application value in functional health product research and development.
Applications
High-End Anti-Aging & Brightening Skincare
Procyanidin is widely used in antioxidant anti-aging essences, glycation repair creams, brightening lotions and daily anti-oxidation skincare formulas. It integrates free radical scavenging, anti-glycation firming and tone-evening multi-effects, effectively improving skin aging, dullness and sagging, serving as a core star active ingredient in natural anti-aging skincare.
Oral Antioxidant Health Supplements
Applied in antioxidant oral capsules, anti-aging functional tablets and metabolic conditioning health products. It targets systemic oxidative stress damage, assists in vascular protection and immune regulation, and provides safe and efficient natural anti-aging solutions for sub-health and aging groups.
Daily Antioxidant Functional Formulas
Used in high-antioxidant functional foods and nutritional fortification products. It improves product free radical-scavenging activity, enhances nutritional value, and provides daily oxidative damage protection for the human body.
Biomedical & Pharmacological Research
Widely used in flavonoid antioxidant mechanism research, anti-glycation pharmacology, vascular protection and cellular immune regulation studies. It acts as a standard high-purity proanthocyanidin monomer for laboratory pharmacological experiments and ingredient activity verification.
Natural Functional Ingredient Innovation
As a high-activity natural flavonoid raw material, it replaces low-activity crude grape seed extracts. It upgrades the antioxidant and anti-aging efficacy of skincare and health products, supports the innovative iteration of dual external and internal anti-aging formulas, and enriches the application system of natural high-efficiency antioxidant ingredients.
FAQ
Q1: What is Procyanidin powder used for?
A: Procyanidin powder is a high-purity natural grape seed flavonoid. It is mainly used for antioxidant anti-aging, anti-glycation firming and brightening skincare, as well as oral antioxidant health care, vascular protection and biomedical oxidative stress research.
Q2: What are the unique advantages of Procyanidin?
A: Different from tannin-based ingredients like Geraniin, Corilagin and Hamamelitannin, Procyanidin is a flavonoid with leading comprehensive antioxidant and anti-glycation potency. It features dual skin and body anti-aging effects, excellent water solubility and high bioavailability, being the preferred natural ingredient for full-dimensional anti-aging formula development.
Q3: Is Procyanidin safe for cosmetic and oral use?
A: Yes, Procyanidin is a pure natural plant-derived active ingredient extracted from edible grape seeds and pine bark. It features mild properties, zero irritation and high biocompatibility, fully complying with international cosmetic-grade and food-grade safety standards, suitable for long-term topical skincare and oral health application.
Q4: What is the difference between Procyanidin and other tannin ingredients?
A: Tannin ingredients focus on anti-glycation, anti-fibrosis, antibacterial and soothing effects, whileProcyanidin specializes in ultra-strong antioxidant and anti-glycation anti-aging. It fills the gap of high-efficiency full-dimensional anti-aging raw materials, forming a perfect complementary functional system with other polyphenol active ingredients.
Q5: How to store Procyanidin powder correctly?
A: Procyanidin powder is sensitive to high temperature and light oxidation. It needs to be tightly sealed, protected from light, and stored at 2-8°C in a dry environment. Standard low-temperature sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Procyanidin samples?
A: Yes, we provide free Procyanidin powder samples for anti-aging skincare formula debugging, antioxidant health product development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
