Product Introduction
| Item | Specification |
| Product Name | Secoisolariciresinol |
| Synonyms | SECO; Secoisolariciresinol |
| CAS Number | 29388-59-8 |
| Molecular Formula | C₂₀H₂₆O₆ |
| Molecular Weight | 362.42 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 112–114°C |
| Boiling Point | 609.1±55.0 °C (Predicted) |
| Solubility | Slightly soluble in water, soluble in ethanol, methanol, DMSO and common organic solvents |
| Natural Source | Naturally extracted from flaxseed, the core active dibenzylbutane-type natural lignan and key enterolignan precursor compound |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry conditions; avoid high temperature, strong light and oxidative deterioration |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Secoisolariciresinol powder is a high-purity natural lignan active ingredient, available in 98% and 99% HPLC grades. Secoisolariciresinol (CAS 29388-59-8), abbreviated as SECO and known as, is a premium dibenzylbutane-type lignan compound exclusively enriched in flaxseed. As the core metabolic precursor of enterolignans in the human body, it features a unique diphenolic lignan structure, delivering dual natural estrogen regulation and high-efficiency antioxidant activity that distinguishes it from polyphenols and stilbene ingredients. It integrates multi-dimensional core benefits including endogenous free radical scavenging, hormone balance regulation, lipid metabolism improvement, anti-obesity, broad-spectrum anti-tumor and neuroprotective effects. Widely applied in anti-aging skincare, female hormone balance health supplements, lipid regulation functional foods and advanced biomedical pharmacological research. As a professional bulk Secoisolariciresinol supplier, we provide high-purity, low-impurity, stable-batch natural lignan raw materials for global industrial and scientific research clients.
Secoisolariciresinol belongs to the high-value natural lignan subclass, with a stable symmetric diphenol structure and unique physiological activation mechanism. Different from resveratrol, pterostilbene and phenolic acid antioxidants, Secoisolariciresinol has exclusive natural phytoestrogen activity and enterolignan conversion advantages. After oral intake, it can be efficiently converted into enterodiol and enterolactone by intestinal flora, exerting long-term hormone regulation and systemic antioxidant protection. Its core functional mechanism activates phase II detoxification enzymes to scavenge intracellular ROS free radicals, inhibit lipid peroxidation and mitochondrial oxidative damage. For skincare, it relieves hormone-related dullness and aging, stabilizes skin microecology and improves aging caused by endocrine imbalance. For body regulation, it competitively binds estrogen receptors, regulates estrogen level balance, inhibits adipocyte accumulation, reduces blood lipid deposition, and blocks the growth of estrogen-dependent tumor cells. With mild properties, high biocompatibility and unique metabolic activation characteristics, it is irreplaceable in hormone balance conditioning and metabolic health management.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Secoisolariciresinol powder adopts low-temperature solvent directional extraction and multi-stage high-precision column chromatography purification technology. We select high-quality mature flaxseed raw materials with stable lignan content, completely remove flaxseed oil, macromolecular proteins, residual sugars and invalid impurities through gradient elution purification, and fully retain the complete lignan molecular structure and biological activity of Secoisolariciresinol. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The refined purification process solves the problems of low natural extraction purity and unstable activity of flaxseed lignans, ensures uniform white crystalline powder appearance and consistent batch efficacy, meeting the strict formula development and high-precision experimental requirements of global customers.
Every batch of Secoisolariciresinol powder undergoes strict multi-dimensional quality inspection, including HPLC high-precision purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished powder features low impurity content, good solubility in common organic solvents, strong structural stability and excellent batch consistency. All products comply with international cosmetic additive regulations, natural functional food safety standards and high-end research-grade compound specifications, supporting safe and standardized application in endocrine conditioning health products, anti-aging skincare, lipid-lowering functional foods and cutting-edge biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Secoisolariciresinol supply. Whether you need hormone-balancing anti-aging active raw materials for high-end skincare formulas, endocrine regulation and lipid metabolism conditioning ingredients for health products, or high-purity lignan compounds for estrogen pharmacology, anti-tumor and neuroprotective mechanism research, our Secoisolariciresinol powder is a cost-effective and high-value bulk raw material choice for global buyers.
Functions & Benefits
High-Efficiency Antioxidant & Mitochondrial Protection (Core Benefit)
Secoisolariciresinol efficiently activates phase II detoxification enzymes in the body, strongly scavenges DPPH, ABTS and intracellular ROS free radicals, inhibits lipid peroxidation and mitochondrial oxidative DNA damage. It reduces systemic oxidative stress, delays cell senescence and skin aging, and builds a long-term stable endogenous antioxidant defense barrier, with lasting antioxidant effects superior to ordinary plant polyphenols.
Natural Phytoestrogen & Hormone Balance Regulation
As a classic natural plant estrogen active ingredient, it competitively binds human estrogen receptors, bidirectionally regulates endocrine balance, improves insufficient or excessive estrogen activity. It effectively relieves hormone-related skin dullness, dry aging and endocrine sub-health problems, and provides mild and safe hormone conditioning for aging skin and menopausal sub-health groups.
Lipid Metabolism Improvement & Anti-Obesity Effect
Secoisolariciresinol significantly inhibits triglyceride accumulation in adipocytes, reduces fat cell proliferation and lipid deposition in the body. It optimizes blood lipid metabolism, lowers LDL cholesterol levels, improves hyperlipidemia and obesity metabolic disorders, and assists in body shaping and cardiovascular health maintenance.
Estrogen-Dependent Anti-Tumor & Chemoprevention
Modern pharmacological studies verify that Secoisolariciresinol effectively inhibits the proliferation and migration of estrogen-dependent malignant tumor cells such as breast cancer and prostate cancer. It blocks tumor cell growth signaling pathways, induces tumor cell apoptosis, and exerts excellent dietary cancer prevention and auxiliary anti-tumor health effects.
Neuroprotective & Anti-Inflammatory Activity
It relieves neuroinflammatory damage caused by oxidative stress, protects nerve cell activity, improves cerebral microcirculation, and alleviates sub-health symptoms such as neurasthenia and cognitive decline caused by aging and endocrine disorders, providing comprehensive nervous system protection.
Intestinal Precursor Activation & Long-Term Body Conditioning
As a key precursor of human enterolignans, Secoisolariciresinol can be converted into high-activity enterodiol and enterolactone by intestinal flora. It achieves long-cycle whole-body anti-oxidation, hormone regulation and immune balance effects, realizing deep and sustained physical conditioning.
Applications
Hormone Balancing Anti-Aging Skincare
Secoisolariciresinol is widely used in endocrine anti-aging essences, mature skin repair creams and hormone stability skincare products. It integrates antioxidant anti-aging, hormone balance regulation and oxidative damage repair multi-effects, effectively improving hormone-related dullness, fine lines, dry aging and sensitive skin problems, being a unique high-end active ingredient for mature skin targeted care.
Endocrine & Metabolic Health Supplements
Applied in female hormone balance products, menopausal conditioning supplements, lipid-lowering and weight management functional products. It bidirectionally regulates endocrine levels, improves menopausal discomfort, optimizes fat metabolism, and provides safe and natural sub-health conditioning for middle-aged and sub-health crowds.
Functional Food & Nutritional Fortification
Used in antioxidant functional foods, flaxseed nutritional fortified products and daily health dietary supplements. It enhances food antioxidant activity, improves human metabolic balance, and upgrades the nutritional and health value of functional foods with natural lignan active ingredients.
Biomedical & Pharmacological Research
Widely used in estrogen endocrine regulation research, lignan metabolic pathway exploration, estrogen-dependent tumor pharmacology and neuroprotective mechanism research, serving as a core standard lignan research compound for university laboratories and medical research institutions.
Natural Lignan Ingredient Innovation
As a core high-value flaxseed lignan monomer, it supports the research and development of hormone-regulating anti-aging and metabolic conditioning functional products, filling the market gap of natural plant estrogen active raw materials and promoting innovative iteration of endocrine health products.
FAQ
Q1: What is Secoisolariciresinol powder used for?
A: Secoisolariciresinol powder is a high-purity natural flaxseed lignan compound. It is mainly used for hormone-balancing anti-aging skincare, female endocrine sub-health conditioning, blood lipid regulation and weight management, as well as biomedical estrogen regulation, anti-tumor and neuroprotective pharmacological research.
Q2: What are the unique advantages of Secoisolariciresinol?
A: Different from common polyphenols and stilbene antioxidants, Secoisolariciresinol has exclusive natural phytoestrogen activity and intestinal conversion activation properties. It realizes long-term systemic hormone balance and metabolic regulation, with targeted advantages in mature skin anti-aging and endocrine health care that ordinary antioxidants do not possess.
Q3: Is Secoisolariciresinol safe for cosmetic and food use?
A: Yes, Secoisolariciresinol is a pure natural plant-derived active ingredient extracted from edible flaxseed. It features mild properties, low irritation and high human compatibility, complying with international cosmetic and food-grade additive safety standards, supporting long-term topical skincare and oral health product application.
Q4: What is the difference between Secoisolariciresinol and other antioxidants?
A: Phenolic acids and stilbenes focus on single antioxidant and anti-inflammatory effects, while Secoisolariciresinol is specialized in hormone balance and metabolic regulation. It can be metabolized and activated in the human body to produce lasting physiological effects, with unique advantages in endocrine anti-aging and lipid health management.
Q5: How to store Secoisolariciresinol powder correctly?
A: Secoisolariciresinol powder is sensitive to high temperature, strong light and oxidation. It needs to be tightly sealed, protected from light, and stored at 2-8°C in a dry environment. Standard low-temperature and light-proof sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Secoisolariciresinol samples?
A: Yes, we provide free Secoisolariciresinol powder samples for hormone anti-aging skincare formula debugging, endocrine health product development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
