
Product Introduction
| Item | Specification |
| Product Name | Vanillic Acid |
| Synonyms | 4-Hydroxy-3-methoxybenzoic acid; |
| CAS Number | 121-34-6 |
| Molecular Formula | C₈H₈O₄ |
| Molecular Weight | 168.15 g/mol |
| Appearance | White crystalline powder with mild vanilla odor |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 208–210°C |
| Boiling Point | 333.9±27.0 °C (Predicted) |
| Solubility | Slightly soluble in cold water, soluble in hot water, ethanol, methanol and DMSO; insoluble in petroleum ether |
| Natural Source | Naturally occurring phenolic acid in vanilla beans, ferula plants, fruits and vegetables, a key intermediate metabolite of vanillin biosynthesis |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at sealed, dark and dry conditions (2-8°C recommended); avoid high temperature, strong light and moisture |
| Shelf Life | 24 months under standard sealed low-temperature storage |
Product Description
Our Vanillic Acid powder is a high-purity natural phenolic acid active ingredient, available in 98% and 99% HPLC grades. Vanillic Acid (CAS 121-34-6), known as 4-Hydroxy-3-methoxybenzoic acid, is a classic natural aromatic phenolic acid widely present in vanilla beans, ferula plants and various fresh fruits. As a core biosynthesis intermediate of vanillin, it features a stable benzene ring phenolic structure, mild natural vanilla fragrance, and dual attributes of flavor fixation and biological activity. It integrates high-efficiency antioxidant, broad-spectrum anti-inflammatory, natural antibacterial and free radical scavenging effects, with unique flavor stabilizing performance, widely applied in natural flavor additives, antioxidant skincare, functional food preservation and biomedical pharmacological research. As a professional bulk Vanillic Acid supplier, we provide high-purity, low-impurity, stable-batch natural phenolic acid raw materials for global industrial and scientific research clients.
Vanillic Acid belongs to the hydroxy-methoxy benzoic acid subclass of phenolic compounds, with phenolic hydroxyl and carboxyl active groups on the molecular parent nucleus, endowing it with excellent biochemical activity and flavor modification capabilities. Different from ordinary flavonoid ingredients, Vanillic Acid has dual core advantages: biological health benefits and natural flavor regulation. Its antioxidant mechanism efficiently scavenges DPPH and intracellular reactive oxygen species, inhibits lipid peroxidation and oxidative cell damage. It significantly suppresses NF-κB inflammatory pathway activation, reduces pro-inflammatory factor release, and relieves chronic low-grade inflammation. In industrial applications, it acts as a high-efficiency flavor fixative, effectively stabilizing vanilla and sweet fragrance systems, improving flavor durability, and avoiding volatile fragrance loss. Meanwhile, it exerts mild broad-spectrum antibacterial and food fresh-keeping effects, delaying product oxidation and deterioration, with ultra-high safety and no peculiar residue for long-term use.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Vanillic Acid powder adopts low-temperature selective solvent extraction and multi-stage high-precision column chromatography purification technology. We select high-quality natural plant raw materials rich in vanillic acid, completely remove plant fibers, macromolecular impurities, residual sugar and invalid pigment components through gradient elution purification, and fully retain the complete molecular structure, natural fragrance and biological activity of Vanillic Acid. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The mature and stable production process ensures consistent batch purity, uniform powder appearance, pure fragrance and reliable activity stability, meeting the strict formula development and experimental requirements of global customers.
Every batch of Vanillic Acid powder undergoes strict multi-dimensional quality inspection, including HPLC purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished white crystalline powder features low impurity content, stable fragrance, good solubility in hot water and organic solvents, and excellent batch consistency. All products comply with international cosmetic additive regulations, natural food additive safety standards and research-grade compound specifications, supporting safe and standardized application in skincare products, natural flavorings, functional foods and biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Vanillic Acid supply. Whether you need natural antioxidant soothing raw materials for skincare formulas, high-efficiency flavor fixation ingredients for food and fragrance products, or high-purity phenolic acid compounds for antioxidant, anti-inflammatory and metabolic pharmacological research, our Vanillic Acid powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
Natural Antioxidant & Anti-Aging (Core Benefit)
Vanillic Acid is a high-activity natural phenolic antioxidant. It efficiently scavenges free radicals such as DPPH and ABTS in the body, inhibits cellular lipid peroxidation and oxidative DNA damage, reduces oxidative stress damage to skin and tissues, enhances endogenous antioxidant defense capacity, and effectively delays aging caused by long-term oxidation, delivering stable and mild anti-aging effects.
Broad-Spectrum Anti-Inflammatory & Skin Soothing
This natural phenolic acid effectively inhibits the activation of NF-κB inflammatory signaling pathway, significantly reducing the release of TNF-α, IL-6 and other pro-inflammatory factors. It relieves acute and chronic low-grade inflammation, calms skin redness, sensitivity and inflammatory irritation caused by external stimuli, stabilizes skin microecology, and provides mild and durable soothing repair effects for fragile skin.
Natural Flavor Fixation & Fragrance Stabilization
As a natural vanilla-derived aromatic ingredient, Vanillic Acid has excellent flavor fixation and fragrance stabilizing properties. It can effectively lock sweet and vanilla fragrance components, reduce volatile fragrance loss, extend fragrance retention time, optimize flavor layering, and solve the problems of weak fragrance and short duration of natural flavor formulas, being a premium natural flavor modifier.
Broad-Spectrum Antibacterial & Food Preservation
Vanillic Acid exerts significant inhibitory effects on common food spoilage bacteria and harmful microorganisms. It can delay food oxidation and microbial reproduction, extend the shelf life of functional foods and beverage products, improve product stability, and achieve safe and green fresh-keeping effects without chemical preservatives.
Metabolic Regulation & Oxidative Damage Relief
Modern pharmacological studies verify that Vanillic Acid can improve systemic oxidative metabolism, reduce inflammatory oxidative damage in tissues, assist in regulating lipid metabolism balance, protect cell membrane integrity, and improve sub-health conditions caused by long-term oxidative stress and inflammatory accumulation.
Mild Barrier Protection & Skin Stabilization
With excellent skin affinity and mild non-irritating properties, Vanillic Acid penetrates superficial skin layers to scavenge excess free radicals, relieve mild inflammatory irritation, assist in repairing fragile skin barriers, enhance skin tolerance, and maintain long-term stable and healthy skin condition.
Applications
Antioxidant Soothing & Fragrance Skincare
Vanillic Acid is widely used in antioxidant anti-aging creams, soothing repair essences, natural fragrance skincare products and sensitive skin maintenance formulas. It integrates antioxidant, anti-inflammatory and soothing effects, while providing pure natural vanilla fragrance fixation, improving product odor and skin care efficacy, suitable for high-end clean beauty formula development.
Natural Food Flavoring & Preservation
Applied in vanilla flavor food, dessert additives, functional beverages and natural preservation formulas. It acts as a natural flavor modifier and fixative to optimize product taste and fragrance, while exerting antioxidant and antibacterial fresh-keeping effects, extending product shelf life and improving food safety.
Daily Chemical & Aromatic Formula Innovation
Used in high-end daily chemical fragrances, aromatic care products and flavor intermediate synthesis. As a natural vanilla flavor intermediate, it stabilizes fragrance systems, enhances fragrance layering and durability, and is a high-value raw material for natural aromatic product iteration.
Biomedical & Scientific Research
Widely used in phenolic antioxidant mechanism research, NF-κB inflammatory pathway pharmacology, metabolic regulation research and plant metabolite analysis, serving as a standard high-purity natural phenolic acid research compound for university laboratories and medical research institutions.
Natural Functional Ingredient Development
Acts as a core natural phenolic intermediate for innovative functional product development, supporting the research and iteration of antioxidant, anti-inflammatory, flavor fixation and green preservation natural raw materials.
FAQ
Q1: What is Vanillic Acid powder used for?
A: Vanillic Acid powder is a high-purity natural phenolic acid extracted from vanilla and plant metabolites. It is mainly used for antioxidant soothing skincare, natural vanilla flavor fixation and food flavor modification, green food preservation, as well as biomedical anti-inflammation and antioxidant pharmacological research.
Q2: What is the difference between Vanillic Acid and Vanillin?
A: Both are vanilla aromatic ingredients. Vanillin is the main aroma source with strong vanilla flavor; Vanillic Acid is its metabolite intermediate, featuring weaker fragrance but stronger antioxidant, anti-inflammatory and flavor fixation effects, more suitable for formula stabilization and functional efficacy addition.
Q3: Is Vanillic Acid safe for cosmetic and food use?
A: Yes, Vanillic Acid is a pure natural plant-derived phenolic acid with mild properties, low irritation and high biocompatibility. It complies with international cosmetic raw material standards and food-grade additive specifications, supporting long-term topical skincare and food formula application.
Q4: What are the core advantages of Vanillic Acid?
A: Vanillic Acid features dual functions of biological activity and flavor fixation, integrating anti-oxidation, anti-inflammation, antibacterial preservation and fragrance stabilization. It has stable molecular properties, mild safety and irreplaceable advantages in natural flavor and functional formula development.
Q5: How to store Vanillic Acid powder correctly?
A: Vanillic Acid powder is sensitive to high temperature, moisture and strong light. It needs to be tightly sealed and stored in a dark, dry and cool environment (2-8°C recommended). Standard sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Vanillic Acid samples?
A: Yes, we provide free Vanillic Acid powder samples for skincare formula debugging, flavor product development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.




