Product Introduction
| Item | Specification |
| Product Name | Pinocembrin |
| Synonyms | 5,7-Dihydroxyflavanone; Dihydrochrysin |
| CAS Number | 480-39-7 |
| Molecular Formula | C₁₅H₁₂O₄ |
| Molecular Weight | 256.25 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity (HPLC) | ≥98.0% / ≥99.0% (customizable) |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.2% |
| Testing Method | HPLC / UV-Vis Spectroscopy / NMR |
| Production Method | Natural Plant Extraction & High-Purity Column Purification |
| Melting Point | 202–203°C |
| Boiling Point | 525.9±50.0 °C (Predicted) |
| Solubility | Soluble in ethanol, methanol, DMSO and organic solvents; slightly soluble in hot water; insoluble in cold water |
| Natural Source | Naturally extracted from propolis, alpinia katsumadai and pine plants, a rare high-activity natural flavanone monomer |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry conditions; avoid high temperature, strong light and oxidation |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our Pinocembrin powder is a high-purity natural bioactive flavanone ingredient, available in 98% and 99% HPLC grades. Pinocembrin (CAS 480-39-7), commonly known as is a rare and high-value flavanone monomer predominantly isolated from natural propolis and alpinia katsumadai. Featuring a stable 5,7-dihydroxyflavanone molecular structure, it stands out from ordinary flavonoids with unique broad-spectrum antibacterial potency, superior neuroprotective activity and efficient antioxidant performance. It integrates multi-core benefits including sterilization and anti-inflammation, nerve cell protection, liver damage repair and anti-oxidative aging, widely applied in antibacterial soothing skincare, neural health supplements, liver protection products and advanced biomedical pharmacological research. As a professional bulk Pinocembrin supplier, we provide high-purity, stable-batch and fully compliant natural flavanone raw materials for global industrial and scientific research clients.
Pinocembrin belongs to the dihydroflavanone subclass of flavonoids, with two hydroxyl active groups on the parent nucleus, endowing it with excellent free radical scavenging ability and unique pharmacological activity. Different from common citrus and licorice flavonoids, Pinocembrin has outstanding broad-spectrum antibacterial properties, effectively inhibiting the activity of various harmful bacteria and fungi. Its core functional mechanism activates the Nrf2/ARE endogenous antioxidant pathway, inhibits NF-κB and MAPK inflammatory signaling cascades, removes intracellular reactive oxygen species, reduces oxidative stress damage, and blocks excessive release of pro-inflammatory factors. In neuroprotection, it improves cerebral microcirculation, protects neurons from ischemic and oxidative damage, and has significant research value in nervous system health care. Meanwhile, it exerts prominent hepatoprotective, anti-aging and anti-allergic effects, with mild properties, high safety and no toxic side effects for long-term topical and oral use.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium Pinocembrin powder adopts low-temperature selective solvent extraction and multi-stage high-precision column chromatography purification technology. We select high-quality natural propolis and alpinia katsumadai raw materials with stable active content, completely remove plant fibers, macromolecular impurities, residual wax and invalid components through gradient elution purification, and fully retain the complete molecular structure and biological activity of Pinocembrin. The entire production process strictly avoids harmful solvent residues and chemical synthetic additives, fully complying with cosmetic-grade, food-grade and research-grade safety standards. The mature and stable production process ensures consistent batch purity, uniform powder appearance and reliable activity stability, meeting the strict formula development and experimental requirements of global customers.
Every batch of Pinocembrin powder undergoes strict multi-dimensional quality inspection, including HPLC purity testing, UV spectral characteristic verification and NMR structural identification to ensure accurate molecular structure and stable high purity. The finished white crystalline powder features low impurity content, good solubility in conventional organic solvents, stable activity and excellent batch consistency. All products comply with international cosmetic additive regulations, natural functional food safety standards and research-grade compound specifications, supporting safe and standardized application in skincare products, health supplements, functional foods and biomedical research projects.
We maintain sufficient inventory and complete qualification documents for bulk Pinocembrin supply. Whether you need natural antibacterial and soothing raw materials for skincare formulas, neuroprotective and liver-protective functional ingredients for health products, or high-purity flavanone compounds for antibacterial pharmacology, nerve protection and antioxidant mechanism research, our Pinocembrin powder is a cost-effective and reliable bulk raw material choice for global buyers.
Functions & Benefits
Broad-Spectrum Antibacterial & Antifungal (Core Unique Benefit)
Pinocembrin is a rare natural flavanone with powerful broad-spectrum antibacterial activity. It significantly inhibits the reproduction and activity of common pathogenic bacteria and fungi, effectively improving skin microbial imbalance, reducing bacterial-induced acne, inflammation and skin problems. As a natural mild antibacterial ingredient, it avoids the irritation and drug resistance risks of chemical antibacterial agents, suitable for long-term skin microbial balance maintenance.
Nrf2 Antioxidant & Anti-Aging
This natural flavanone specifically activates the Nrf2 endogenous antioxidant pathway, efficiently scavenges DPPH, ABTS and intracellular reactive oxygen free radicals, inhibits cellular lipid peroxidation and oxidative DNA damage, enhances the body’s antioxidant defense capacity, and delays skin and systemic aging caused by long-term oxidative stress, delivering stable anti-aging effects.
Broad-Spectrum Anti-Inflammatory & Sensitive Skin Soothing
Pinocembrin effectively inhibits NF-κB and MAPK inflammatory pathway activation, reduces the release of TNF-α, IL-6 and other pro-inflammatory factors, relieves acute and chronic low-grade inflammation. It calms skin redness, swelling and itching caused by microbial infection and external irritation, stabilizes skin microecology, and provides mild and efficient soothing repair effects for sensitive and acne-prone skin.
Unique Neuroprotective & Cerebral Protection Effects
Modern pharmacological studies verify that Pinocembrin has significant neuroprotective activity. It improves cerebral blood microcirculation, protects nerve cells from oxidative damage and ischemic injury, reduces neuronal apoptosis, and plays a positive regulatory role in maintaining nervous system health, with unique application advantages in brain health care products.
Hepatoprotective & Oxidative Damage Repair
Pinocembrin protects liver cells from oxidative stress and toxic stimulation, inhibits liver inflammatory infiltration and cell damage, optimizes liver metabolic and detoxification functions, repairs mild liver injury, and effectively improves liver sub-health caused by long-term oxidative damage and metabolic disorders.
Skin Barrier Stabilization & Microecology Balance
With excellent skin affinity and mild activity, Pinocembrin regulates skin surface microbial balance, reduces harmful microbial proliferation, repairs damaged skin barriers, enhances skin tolerance, and maintains long-term healthy and stable skin condition, ideal for problematic and sensitive skin care.
Applications
Antibacterial Acne & Sensitive Skin Skincare
Pinocembrin is widely used in antibacterial acne essences, soothing repair lotions, sensitive skin care products and microecology balancing formulas. It features natural sterilization and anti-inflammatory effects, improves acne and inflammatory skin problems, stabilizes skin microecology, and is a high-value clean active ingredient for mild problem skin care.
Neuroprotective & Liver Protection Health Supplements
Applied in nervous system health products, brain function maintenance formulas, liver protection detox supplements and daily antioxidant health products. It protects nerve and liver cells, improves microcirculation, enhances systemic antioxidant capacity, and provides comprehensive sub-health conditioning for long-term fatigued and aging groups.
Functional Food & Nutritional Fortification
As a safe natural flavanone with antibacterial and antioxidant properties, Pinocembrin is used in functional health foods, nutritional fortified products and daily dietary supplements. It improves product antioxidant and antibacterial preservation performance, enhancing nutritional value and product stability.
Biomedical & Scientific Research
Widely used in neuroprotective pharmacology, antibacterial mechanism research, Nrf2 antioxidant pathway exploration, liver protection pharmacodynamics and microecology research, serving as a standard high-purity natural flavanone research compound for university laboratories and medical research institutions.
Natural Functional Ingredient Innovation
Acts as a high-value flavanone intermediate for innovative functional product development, supporting the research and iteration of antibacterial, neuroprotective, antioxidant and liver-protective natural raw materials.
FAQ
Q1: What is Pinocembrin powder used for?
A: Pinocembrin powder is a high-purity natural flavanone extracted from propolis and alpinia katsumadai. It is mainly used for natural antibacterial acne removal and skin soothing skincare, neuroprotection and liver protection health conditioning, as well as biomedical antibacterial, anti-inflammatory and nerve protection pharmacological research.
Q2: What makes Pinocembrin different from other flavonoids?
A: Unlike conventional citrus and licorice flavonoids that focus on anti-oxidation and anti-inflammation, Pinocembrin has unique broad-spectrum natural antibacterial activity and exclusive neuroprotective effects, making it the preferred raw material for acne skincare and neural health product development.
Q3: Is Pinocembrin safe for long-term use?
A: Yes, Pinocembrin is a pure natural plant-derived flavanone with ultra-mild properties, no irritation and high biocompatibility. It complies with international cosmetic raw material standards and food-grade safety specifications, supporting long-term topical skincare and oral health product application.
Q4: What are the core advantages of Pinocembrin?
A: Pinocembrin features natural broad-spectrum antibacterial activity and unique neuroprotective efficacy, integrating anti-oxidation, anti-inflammation and liver protection multi-effects. It has mild and safe properties without drug resistance, with irreplaceable advantages in problem skincare and nerve health fields.
Q5: How to store Pinocembrin powder correctly?
A: Pinocembrin powder is sensitive to high temperature, strong light and oxidation. It needs to be tightly sealed and stored at 2-8°C in a dark and dry environment. Standard low-temperature sealed storage ensures a 24-month valid shelf life.
Q6: Can I get free Pinocembrin samples?
A: Yes, we provide free Pinocembrin powder samples for skincare formula debugging, functional food development and academic pharmacological research. Bulk orders support customized purity and packaging to meet diverse production and research needs.
