Lupeol CAS 545-47-1 Pentacyclic Triterpene Alcohol from Lupinus& Mangifera indica
Product Identification
| Item | Detail |
|---|---|
| Synonyms | Lupeol; Fagarsterol; (3β)-Lup-20(29)-en-3-ol |
| CAS RN | 545-47-1 |
| Molecular Formula | C₃₀H₅₀O |
| MW | 426.73 |
| Triterpene Type | Pentacyclic lupane |
| Botanical Sources | Lupinusspp.; Mangifera indica(mango peel); Artemisiaspp.; Rosmarinus officinalis; Syzygium aromaticum |
| HS Code (ref) | 1302 / 2938 |
| Sibling Trio | Oleanolic Acid 805-44-0; Ursolic Acid 77-52-1 |
Description
Lupeol is a pentacyclic lupane-type triterpene alcohol (C3-OH, C20(29)-exomethylene) found across 100+ botanicals. Unlike the oleanane pair (OA/UA) which dominate “apple peel / olive leaf” DTC stories, lupeol’s literature signal clusters on:
- TRPV1 modulation (vanilloid receptor, sensory/anti-nociceptive — the angle that differentiates lupeol from OA/UA)
- STAT3 & NF-κB (anticancer R&D, oral squamous, prostate, pancreatic lines in literature)
- Acne & barrier (sebum-modulate + anti-inflammatory, lupeol-specific vs. OA/UA which lean anti-aging)
Applications
Cosmeceutical – Acne & Barrier – lupeol mono or “Centella + Luteolin + Feverfew + Lupeol” soothing quadruple; sensitive / acne-prone / post-procedure; INCI Lupeol(if purified) or Mangifera Indica Fruit Extract(crude)
DTC Fruit Triterpene Wellness – mango peel / rosemary / clove “botanical triterpene by-product” sustainability; stacked OA+UA+Lupeol “triterpene trio”; traditional gut/liver wellness
Pharma R&D – TRPV1 & STAT3 – non-pungent TRPV1 modulator (vs. capsaicin), STAT3/NF-κB anticancer screening; links to Quercetin (NF-κB) & Parthenolide (NF-κB/STAT3) inner-cluster
By-product Stream – Feed & Cosmetic Base – mixed triterpene (Lupeol+OA+UA 20–60%) from mango-peel OA isolation; low-cost cosmetic base, ruminant pasture (Lupinus) triterpene interest
