Andrographolide Powder (CAS 5508-58-7) – 98% HPLC | Natural Immune Ingredient

Product Description
Andrographolide is a labdane diterpenoid lactone isolated from the leaves and stems of Andrographis paniculata(King of Bitters, ), a medicinal plant traditionally used in Ayurveda and Traditional Chinese Medicine. It is recognized as the primary bioactive marker of the herb, responsible for its anti-inflammatory, antiviral, immunomodulatory, and hepatoprotective properties.
Compared with synthetic antibiotics, Andrographolide is marketed as a “natural antibiotic” ingredient in dietary supplements targeting seasonal immune support, upper respiratory health, and inflammatory balance. Our material is HPLC-standardized, off-white to white crystalline powder, available in 98% and 99% grades for nutraceutical and pharmaceutical use.
Basic Information
| Item | Detail |
|---|---|
| CAS Number | 5508-58-7 |
| Molecular Formula | C₂₀H₃₀O₅ |
| Molecular Weight | 350.45 |
| Appearance | White to off-white crystalline powder / prismatic crystals |
| Melting Point | 229–232 °C |
| Solubility | Soluble in methanol, ethanol, acetone; poorly soluble in water |
| Purity (HPLC) | 98% / 99% |
| Plant Source | Andrographis paniculata(leaves / whole herb) |
| Storage | Cool, dry, protected from light; 2–8 °C preferred for long term |
| Shelf Life | 2 years |
Applications

Dietary Supplements: immune capsules, seasonal respiratory blends, “natural antibiotic” formulas
Functional Foods / TCM extracts: Andrographis standard extracts (usually 10%–98% Andrographolide)
Pharmaceutical R&D: parent compound for water-soluble derivatives (e.g. Potassium Dehydroandroandrographolide Succinate – 炎琥宁; Sodium Andrographis Sulfonate – 穿琥宁)
Veterinary / Aquaculture: anti-infective feed additive (region-dependent)
