Product Introduction
| Item | Specification |
| Product Name | p-Cresol |
| Synonyms | 4-Methylphenol; para-Cresol; 4-Hydroxytoluene |
| CAS Number | 106-44-5 |
| Molecular Formula | C₇H₈O |
| Molecular Weight | 108.14 g/mol |
| Appearance | Colorless transparent crystalline solid, turns pale pink upon long-term oxidation, with characteristic mild phenolic odor |
| Purity (GC) | ≥99.5% (Industrial Grade / Fine Chemical Grade, customizable) |
| Loss on Drying | ≤ 0.3% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | GC / HPLC / NMR / Mass Spectrometry |
| Production Method | Crude Phenol Fractionation & High-Vacuum Precision Distillation + Recrystallization Purification |
| Melting Point | 32–34°C (lit.) |
| Boiling Point | 201–203°C (lit.) |
| Density | 1.03 g/cm³ at 25°C |
| Refractive Index | n20/D 1.539 |
| Solubility | Slightly soluble in water, freely soluble in ethanol, ether, chloroform and most organic solvents, good compatibility with resin and antioxidant synthesis systems |
| Chemical Characteristic | Para-methyl substituted phenolic structure, high crystallinity, excellent alkylation selectivity, strongest antioxidant derivation ability among three cresol isomers |
| Package | 1 kg/fluorinated bottle, 25 kg/plastic drum; custom packaging available |
| Storage | Store at 2-8°C in sealed, dark and dry conditions; avoid air oxidation and long-term light exposure to prevent discoloration |
| Shelf Life | 24 months under standard low-temperature sealed storage |
Product Description
Our p-Cresol is a high-purity industrial-grade para-isomer phenolic monomer with 99.5% GC purity. p-Cresol (CAS 106-44-5), also known as 4-Methylphenol or is one of the three core isomers in the cresol family, possessing highly differentiated industrial application value. Different from o-Cresol (resin curing focus) and m-Cresol (polymer solvent & vitamin intermediate focus), p-Cresol is specialized in high-efficiency antioxidant derivation and fine chemical synthesis, serving as the exclusive and optimal raw material for manufacturing rubber & plastic antioxidants. It features high structural stability, excellent alkylation reaction selectivity and high crystallinity, occupying an irreplaceable core position in the antioxidant and agrochemical intermediate industry chains. As a professional bulk p-Cresol supplier, we provide low-impurity, high-selectivity, stable-batch p-Cresol raw materials for global rubber chemical, new material and fine chemical enterprises.
p-Cresol has unique structural and performance advantages among cresol isomers. Its para-methyl symmetrical structure endows it with higher molecular stability and reaction specificity compared with ortho and meta isomers. It is the only preferred raw material for industrial synthesis of 2,6-di-tert-butyl-p-cresol (Antioxidant 264), the most widely used universal antioxidant for plastics, rubber and petroleum products. In resin applications, p-Cresol can modify phenolic resins to improve product weather resistance, aging resistance and mechanical stability. In addition, it can be used for the synthesis of high-efficiency pesticides, fragrances and pharmaceutical intermediates, with high reaction conversion rate and few by-products. Unlike vanilla-series phenolic products focused on flavor and skincare, p-Cresol is fully industrial-oriented, highlighting antioxidant synthesis and high-purity fine chemical derivation value.
Manufactured by Shaanxi BAISFU Bio-Engineering Co., Ltd., our premium p-Cresol adopts crude phenol fractional distillation combined with multi-stage high-vacuum precision distillation and recrystallization purification technology. We thoroughly separate o-cresol, m-cresol and other impurity isomers, completely remove tar residues, heavy metals and non-phenolic miscellaneous impurities, and fully retain the pure para-methylphenol symmetrical active structure. The whole production process complies with strict fine chemical grade standards, effectively solving the common problems of mixed isomer interference, low synthesis selectivity and easy discoloration of ordinary industrial p-Cresol. The finished product presents uniform colorless crystal state, stable chemical activity and excellent batch consistency, fully meeting the high-precision raw material requirements of antioxidant mass production and fine chemical synthesis.
Every batch of p-Cresol undergoes strict multi-dimensional quality inspection, including GC high-precision single-isomer purity analysis, NMR structural verification and mass spectrometry molecular identification to ensure ultra-low isomer impurity content and accurate molecular structure. The product features stable physical and chemical properties, moderate melting point, convenient industrial batching and processing, and excellent compatibility with various organic synthesis systems. All indicators meet international industrial fine chemical standards, supporting stable and efficient large-scale industrial applications in antioxidant manufacturing, resin modification, pesticide intermediate synthesis and scientific research experiments.
We maintain sufficient inventory and complete qualification documents for bulk p-Cresol supply. Whether you need high-selectivity raw materials for rubber/plastic antioxidant production, modified monomers for weather-resistant phenolic resins, or standard high-purity intermediates for pesticide and fine chemical synthesis, our high-purity p-Cresol is a cost-effective and high-value industrial phenolic raw material choice for global buyers.
Functions & Benefits
Exclusive Antioxidant Synthesis Precursor (Core Benefit)
p-Cresol is the sole optimal raw material for synthesizing Antioxidant 264 (2,6-di-tert-butyl-p-cresol), the most mainstream universal antioxidant in the industry. Its para-substituted symmetrical structure ensures ultra-high selectivity in tert-butylation reaction, with high conversion rate and pure product quality, effectively improving the anti-aging and anti-oxidation performance of rubber, plastic and polymer materials.
High-Stability Resin Modification Performance
p-Cresol can be used for phenolic resin modification and synthesis. It significantly improves the weather resistance, thermal stability and aging resistance of resin products, enhances surface hardness and dimensional stability, and solves the problem of easy yellowing and brittle failure of ordinary phenolic resins during long-term use.
High-Selectivity Fine Chemical Derivation
With stable para-methyl active structure, p-Cresol exhibits excellent reaction specificity in alkylation, nitration and condensation reactions. It is widely derived into high-value fine chemicals such as pesticide intermediates, synthetic fragrances and pharmaceutical auxiliary materials, with stable reaction process and controllable by-products, suitable for large-scale industrial continuous production.
Excellent Anti-Aging & Stabilizing Activity
The monomer itself has certain antioxidant and free radical scavenging capabilities. When applied in material formulas, it can inhibit thermal oxidation degradation and ultraviolet aging of polymer materials, extend product service life, and improve formula stability and storage resistance.
Superior Crystallinity & Batch Consistency
High-purity p-Cresol purified by recrystallization has uniform crystal form, low moisture content and ultra-low mixed isomer impurities. It avoids performance fluctuation of downstream products caused by impurity interference, ensuring consistent quality of industrial synthesized antioxidants and modified resins.
Good Formula Compatibility & Processability
p-Cresol has excellent solubility in organic solvents and good compatibility with polymer monomers and chemical synthesis systems. It features moderate melting point, easy melting and batching, convenient industrial operation, and stable performance in long-term cyclic production.
Applications
Rubber & Plastic Antioxidant Manufacturing
p-Cresol is the core exclusive raw material for industrial production of Antioxidant 264. It is widely used in the synthesis of anti-aging additives for rubber, plastic, resin, lubricating oil and petroleum products, effectively preventing material oxidation, yellowing and aging, and improving product durability.
Modified Phenolic Resin & New Material Industry
Applied in the preparation of high weather resistance and high stability modified phenolic resins, insulating materials and adhesive products. It optimizes the thermal stability and mechanical properties of resins, and is suitable for high-end polymer material and electronic insulating material manufacturing scenarios.
Pesticide & Pharmaceutical Intermediate Synthesis
Used for the derivation of high-efficiency pesticide intermediates, bactericidal raw materials and pharmaceutical phenolic auxiliary substances. Its high-purity single-isomer structure ensures high purity and high activity of downstream fine chemical products, meeting green chemical production standards.
Synthetic Fragrance & Daily Chemical Auxiliaries
As a fine chemical intermediate, it can be used for the synthesis of special spice compounds and daily chemical additive raw materials, providing stable phenolic base tone and structural support for high-end fine fragrance formulas.
Laboratory Research & Custom Synthesis
As a standard high-purity p-cresol single isomer reagent, it is used for phenolic structure reaction mechanism research, antioxidant formula development and new material modification experiments, providing high-stability raw material support for scientific research and customized industrial production.
FAQ
Q1: What is p-Cresol used for?
A: p-Cresol is a high-purity para-methylphenol industrial monomer. It is mainly used as the exclusive precursor for rubber/plastic Antioxidant 264 synthesis, high-stability modified phenolic resin monomer, and key intermediate for pesticides, pharmaceuticals and fine chemical derivatives.
Q2: What is the difference between p-Cresol, o-Cresol and m-Cresol?
A: o-Cresol focuses on resin curing and cross-linking; m-Cresol focuses on polymer solvent and vitamin E intermediates; p-Cresol focuses entirely on antioxidant synthesis and high-selectivity fine chemical derivation. The three isomers have completely differentiated industrial application scenarios and cannot replace each other.
Q3: Why is p-Cresol the best choice for antioxidant production?
A: Only p-Cresol has the symmetrical para-methyl structure, which provides ultra-high selectivity in tert-butylation reaction for synthesizing Antioxidant 264. Other cresol isomers will produce a large number of by-products with low yield and poor product purity, so p-Cresol is the exclusive industrial raw material.
Q4: Is p-Cresol stable during storage?
A: High-purity p-Cresol has stable molecular structure, but it is prone to slight oxidation and pink discoloration when exposed to air and light. Sealed, low-temperature and dark storage can effectively maintain its original crystal state and chemical activity, ensuring a 24-month shelf life.
Q5: What is the physical state of p-Cresol?
A: p-Cresol is a colorless transparent crystalline solid at room temperature with a melting point of 32–34°C. It melts into clear liquid after heating, with mild phenolic odor, easy for industrial batching and synthesis operation.
Q6: Can I get free p-Cresol samples?
A: Yes, we provide free p-Cresol samples for antioxidant formula debugging, resin modification experiments and fine chemical synthesis research. Bulk orders support customized purity and packaging to meet large-scale industrial production needs.
