Chrysin CAS :480-40-0
Chrysin Powder (CAS 480-40-0) is a natural flavonoid extracted from Passiflora coerulea, widely used in dietary supplements and cosmetic formulations. As a premium Chrysin Powder ingredient, it delivers scientifically documented antioxidant, anti-inflammatory, and hormonal-modulating benefits for diverse health and beauty applications. Produced using advanced extraction and purification technology from premium natural botanical sources, each production batch undergoes strict quality control through HPLC and UV-Vis spectroscopy, ensuring a consistent purity of ≥ 98% that meets international standards for dietary supplements, pharmaceuticals, and cosmetic ingredients. Naturally derived with scientifically documented antioxidant, anti-inflammatory, and hormonal-modulating properties, Chrysin Powder serves as a key raw material in testosterone support formulations, sports nutrition products, anti-aging cosmetics, and functional food ingredients. Our commitment to quality, traceability, and regulatory compliance makes us a trusted global supplier of Chrysin to over 50 countries. Functions & Benefits Potent Antioxidant — Chrysin effectively scavenges free radicals, reduces oxidative stress at the cellular level, and protects tissues from oxidative damage. Anti-Inflammatory Support — Chrysin inhibits COX-2 gene expression and suppresses prostaglandin E₂ production, providing significant anti-inflammatory effects. Testosterone Support — As a natural aromatase inhibitor, Chrysin helps support healthy testosterone levels by reducing the conversion of testosterone to estrogen. Anxiety & Stress Relief — Chrysin acts as a ligand for central benzodiazepine receptors, exhibiting notable anxiolytic effects without sedative side effects. Neuroprotective Effects — Chrysin has demonstrated the ability to reduce infarct volume and improve neurological outcomes in ischemia/reperfusion injury models. Anti-Cancer Potential — Chrysin has shown promising anti-cancer activity through multiple mechanisms including inhibition of HIF-1α expression and induction of apoptosis.

Product Introduction
| Item | Detail |
|---|---|
| Product Name | Chrysin |
| Synonyms | 5,7-Dihydroxyflavone; Chrysine; 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one |
| CAS Number | 480-40-0 |
| Molecular Formula | C₁₅H₁₀O₄ |
| Molecular Weight | 254.24 g/mol |
| Appearance | Light yellow crystalline powder |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Testing Method | HPLC / UV-Vis Spectroscopy |
| Extract Method | Plant Extraction & Purification |
| Melting Point | 284°C – 286°C |
| Solubility | Slightly soluble in DMSO, methanol, ethanol, acetone; insoluble in water |
| Source | Naturally derived from propolis, honey, passionflower (Passiflora incarnata) |
| Package | 1 kg/aluminum foil bag, 25 kg/fiber drum; custom packaging available |
| Storage | Store in a cool, dry place; keep tightly sealed and protected from light and heat |
| Shelf Life | 24 months when stored properly in original packaging |
Functions & Benefits
Potent Antioxidant — Chrysin effectively scavenges free radicals, reduces oxidative stress at the cellular level, and protects tissues from oxidative damage. It supports the body’s natural defense system against environmental stressors and contributes to overall health and longevity.
Anti-Inflammatory Support — Chrysin inhibits COX-2 gene expression and suppresses prostaglandin E₂ (PGE₂) production, providing significant anti-inflammatory effects. This makes it valuable in managing chronic inflammation and supporting joint and cardiovascular health.
Testosterone Support — As a natural aromatase inhibitor, Chrysin helps support healthy testosterone levels by reducing the conversion of testosterone to estrogen. This property has made it one of the most popular ingredients in men’s health supplements, sports nutrition, and bodybuilding formulations worldwide.
Anxiety & Stress Relief — Research indicates that Chrysin acts as a ligand for central benzodiazepine receptors, exhibiting notable anxiolytic (anti-anxiety) effects without the sedative side effects associated with synthetic alternatives. It promotes relaxation and emotional well-being.
Neuroprotective Effects — In preclinical studies, Chrysin has demonstrated the ability to reduce infarct volume and improve neurological outcomes in ischemia/reperfusion injury models. It works by decreasing pro-inflammatory gene expression and mitigating oxidative damage in neural tissues.
Anti-Cancer Potential — Chrysin has shown promising anti-cancer activity through multiple mechanisms: inhibition of HIF-1α expression, induction of apoptosis, and modulation of critical signaling pathways including NF-κB, PI3K/Akt, and TGF-β/Smad. These properties are under active investigation for potential therapeutic applications.
Applications
Dietary Supplements — Chrysin is a premium ingredient in testosterone boosters, men’s health formulas, anti-aging supplements, and general wellness products. Available formulations include capsules, tablets, softgels, and powdered blends.
Sports Nutrition — Widely incorporated into pre-workout boosters, post-workout recovery formulas, protein blends, and bodybuilding supplements. Chrysin’s potential to support natural testosterone levels makes it a staple in performance nutrition lines.
Pharmaceutical Industry — Used as an active pharmaceutical ingredient (API) and key intermediate in drug development programs targeting anti-inflammatory, neuroprotective, anti-cancer, and anti-diabetic therapeutics.
Cosmetics & Personal Care — Added to anti-aging creams, serums, lotions, and skin-conditioning formulations. Chrysin’s antioxidant properties help protect skin from environmental damage, reduce signs of aging, and improve overall skin health.
Functional Foods & Beverages — Utilized as a natural bioactive additive in health drinks, nutritional bars, functional snacks, and fortified food products designed to deliver antioxidant and wellness benefits.
Health Products & Herbal Medicine — Formulated into herbal extracts, traditional medicine preparations, and natural health products targeting inflammation management, stress relief, hormonal balance, and immune support.
Company Profile
Founded in 2019 and headquartered in Xi’an, China, we specialize in the R&D, production, and global distribution of premium natural plant extracts, food flavors & fragrances, functional food additives, and health supplement raw materials.
With our own raw material bases, state-of-the-art manufacturing facilities, and a dedicated R&D team, we serve customers across 50+ countries spanning the European Union, North America, Central & South America, and beyond.
Every product is manufactured under strict quality management systems and undergoes comprehensive third-party testing to ensure purity, safety, and regulatory compliance.





